Development Research Program

发展研究计划

• 批准号: 10683958
• 负责人: Stephanie S Watowich
• 金额: $ 9.52万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-16 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10683958
• 关键词: Acceleration; Authorization documentation; Award; Bioinformatics; Biology; Biometry; Budgets; Clinical; Clinical Research; Collaborations; Communication; Creativeness; Cutaneous Melanoma; Data; Data Analyses; Development; Eligibility Determination; Environment; Evaluation; Faculty; Funding; Funding Agency; Future; Grant; Guidelines; Immune response; Immunotherapy; Incidence; Institution; Laboratories; Medical center; Methods; Minority; Monitor; Morbidity - disease rate; Outcome; Patient-Focused Outcomes; Patients; Peer Review; Philanthropic Fund; Pilot Projects; Postdoctoral Fellow; Prevention; Reproduction spores; Research; Research Design; Research Personnel; Research Project Grants; Resources; Role; Sampling; Scientist; Site; Societies; Testing; Texas; Tissues; University of Texas M D Anderson Cancer Center; Uveal Melanoma; Woman; Writing; design; feasibility testing; flexibility; follow-up; high reward; high risk; innovation; interest; melanoma; novel; parent grant; programs; research and development

Developmental Research Program: Project Summary/Abstract This SPORE in Melanoma Developmental Research Program (DRP) serves to identify and fund pilot projects that take maximum advantage of new research breakthroughs and novel ideas that may eventually reduce the incidence and morbidity or increase the survival of patients with melanoma. Progress in understanding of melanoma biology and the role of immune response in melanoma patient outcomes has led to substantial advances in both targeted and immunotherapies for melanoma patients, and much promise is held for immediate future advances. Therefore, we are particularly interested in leveraging novel ideas from investigators with a variety of expertise in this DRP, and providing seed money for testing creative hypotheses and obtaining preliminary data for projects that are not supported by current or alternative funding sources. High risk/high reward pilot projects are especially prioritized, and applications from women and minority or underserved investigators are strongly encouraged. The available DRP funds include the required $50,000 annually throughout the duration of the SPORE award, as well as an annual contribution of up to $100,000 from institutional “matching funds,” for a total of $150,000 per year. Applications for SPORE DRPs are solicited annually, with an aim to fund at least 3 one-year awards of up to $50,000 each, with the possibility of ongoing support for a second year award of $50,000 if requested and approved based on acceptable progress. Philanthropic funds will also be utilized if available to support high quality proposals. Projects that provide a “pipeline” of additional value to the main SPORE projects or that support other new or concurrent melanoma grants are welcomed.

发展研究计划：项目摘要/摘要 黑色素瘤孢子发展研究计划 (DRP) 旨在确定和资助试点项目 最大限度地利用新的研究突破和新颖的想法，最终可能减少 黑色素瘤的发病率和发病率或增加患者的生存率的进展。 黑色素瘤生物学和免疫反应在黑色素瘤患者预后中的作用已导致大量 黑色素瘤患者的靶向治疗和免疫治疗取得了进展，并且前景广阔 因此，我们对利用来自未来的新想法特别感兴趣。 在此 DRP 方面拥有各种专业知识的研究人员，并为测试创造性假设提供种子资金 获取当前或替代资金来源不支持的项目的初步数据。 高风险/高回报试点项目尤其受到优先考虑，来自妇女和少数民族或 强烈鼓励服务不足的调查人员使用可用的 DRP 资金，其中包括所需的 50,000 美元。 在 SPORE 奖励期间每年提供高达 100,000 美元的捐款 每年从机构“配套资金”中募集总计 150,000 美元的 SPORE DRP 申请。 每年一次，目标是资助至少 3 个一年期奖项，每个奖项最高 50,000 美元，并有可能持续进行 如果根据可接受的进展提出请求并获得批准，则支持第二年 50,000 美元的奖励。 如果有的话，慈善资金也将用于支持提供高质量提案的项目。 对主要 SPORE 项目具有附加价值或支持其他新发或并发黑色素瘤的“管道” 欢迎赠款。