2014 Chemotactic Cytokines Gordon Research Conference and Gordon Research Seminar

2014年趋化细胞因子戈登研究大会暨戈登研究研讨会

基本信息

批准号：
8708388
负责人：
ANDREW D LUSTER
金额：
$ 1.1万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-03-01 至 2014-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8708388
关键词：
Affect Age Area Asians Autoimmune Diseases Autoimmunity Biochemical Biological Brain Cell Communication Cells Chemotactic Factors Clinic Clinical Research Collaborations Communicable Diseases Complex Country Cytokine Gene Development Discipline Disease Embryonic Development Emigrations Ensure Environment European Family Feedback Fees Fertilization Fostering Funding Future Future Generations Gene Family Generations Goals Health Host Defense Human Human Genome Immune Immunity Infection Inflammation Inflammatory Intervention Journals Lead Leukocytes Link Malignant Neoplasms Medical Mentors Molecular Neoplasm Metastasis Oral Organ Participant Pathogenesis Pathologic Processes Pathway interactions Physiological Processes Play Positioning Attribute Postdoctoral Fellow Request for Applications Research Research Personnel Research Project Grants Role Scientist Seasons Senior Scientist Series Signal Transduction Social Interaction Specialist Students Therapeutic Thinking Time Tissues Translations Travel United States National Institutes of Health Work abstracting age group base cell type chemokine chemokine receptor empowered experience frontier graduate student human disease innovation intercellular communication medical specialties meetings migration novel novel strategies peer planetary Atmosphere posters professor programs public health relevance receptor research study success symposium therapeutic target tumor growth

项目摘要

PROJECT SUMMARY Chemokines, the structurally homologous, functionally distinct family of chemotactic cytokines together with their cognate classical signaling and atypical non-signaling receptors comprise a complex molecular network involved in nearly all aspects of human health and disease. The 2014 Gordon Research Conference (GRC) on Chemotactic Cytokines: Positioning Cells in Immunity and Disease is a world premier meeting devoted entirely to understanding these important molecules. This will be our 11th Chemokine GRC, which has been held every other year since 1994, when chemokines first burst onto the scene as the largest cytokine gene family in the human genome. Similar to each preceding conference in this series, Chemokine GRC 2014 will bring together scientists from a broad range of biomedical disciplines to showcase the latest unpublished research findings that cover all aspects of chemokine function and provide a high-quality scientific forum to discuss their potential implications, including translation to the clinic. The program of this meeting will cover basic biochemical and biological aspects of chemokines as related to their contributions to leukocyte migration and emigration, immune tissue organization and function, and their role in inflammation, infection, autoimmunity and cancer. In addition, due to the success of the first Gordon Research Seminar (GRS) on Chemotactic Cytokines in 2012, we will be having this satellite meeting for bench scientists at the graduate and postdoctoral level again in 2014 titled Frontiers in Chemokine Research. GRS provides a forum where young researchers (e.g., students and post-doctoral fellows) can present their work and receive feedback on their ongoing research projects from their peers and a selected panel of senior experts. GRS will promote grassroots level integration and networking within the field of chemokine research. NIH funding is requested to provide partial support for registration for participants. We fully anticipate that the scientific discussions, research talks, poster sessions, and informal interactions between the participants of this conference will contribute to advancing our understanding of molecular mechanisms of chemokine involvement in disease pathogenesis. This will lay the ground work for the development of new collaborative projects, which will lead to new discoveries and ultimately new therapies and approaches to treat debilitating human disease, including inflammatory, infectious and autoimmune diseases and cancer.

项目概要趋化因子是结构同源、功能不同的趋化细胞因子家族它们的同源经典信号传导和非典型非信号传导受体构成了一个复杂的分子网络几乎涉及人类健康和疾病的各个方面。 2014 年戈登研究会议 (GRC) 趋化细胞因子：细胞在免疫和疾病中的定位是一场全球首屈一指的会议了解这些重要的分子。这将是我们的第 11 届 Chemokine GRC，每年举办一次自 1994 年以来，趋化因子作为最大的细胞因子基因家族首次出现。人类基因组。与本系列之前的每次会议类似，Chemokine GRC 2014 将汇集来自广泛生物医学学科的科学家展示最新未发表的研究成果涵盖趋化因子功能的各个方面，并提供一个高质量的科学论坛来讨论其潜力影响，包括转化为临床。本次会议的议程将涵盖基础生化和趋化因子的生物学方面与其对白细胞迁移和移出的贡献有关，免疫组织的组织和功能，及其在炎症、感染、自身免疫和癌症中的作用。在此外，由于2012年第一届戈登趋化细胞因子研究研讨会（GRS）的成功举办，我们将于 2014 年再次为研究生和博士后级别的基础科学家举办卫星会议标题为“趋化因子研究前沿”。 GRS 提供了一个论坛，年轻的研究人员（例如学生和博士后研究员）可以展示他们的工作并获得有关他们正在进行的研究项目的反馈他们的同行和选定的高级专家小组。 GRS将促进基层融合趋化因子研究领域内的网络。请求 NIH 资助以提供部分支持参与者注册。我们完全期待科学讨论、研究讲座、海报会议、本次会议与会者之间的非正式互动将有助于推进我们的了解趋化因子参与疾病发病机制的分子机制。这将奠定为开发新的合作项目奠定基础，这将带来新的发现和最终治疗使人衰弱的疾病的新疗法和方法，包括炎症、传染病以及自身免疫性疾病和癌症。