2012 Chemotactic Cytokines Gordon Research Conference & Gordon Research Seminar

2012年趋化细胞因子戈登研究会议

基本信息

批准号：
8307657
负责人：
ANDREW D LUSTER
金额：
$ 0.7万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-03-01 至 2013-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8307657
关键词：
Affect Age Age-Years American Area Autoimmune Diseases Autoimmunity Biochemical Biological Brain Cell Communication Cells Chemotactic Factors Clinic Clinical Research Collaborations Communicable Diseases Complex Country Cytokine Gene Development Discipline Disease Embryonic Development Emigrations Ensure Environment Europe Feedback Fees Fertilization Fostering Future Future Generations Gene Family Generations Goals Growth Health Host Defense Human Human Genome Immune Inflammation Inflammatory Intervention Journals Leukocytes Link Malignant Neoplasms Medical Mentors Molecular Neoplasm Metastasis Oral Organ Participant Pathogenesis Pathologic Processes Pathology Pathway interactions Physiological Processes Play Postdoctoral Fellow Recording of previous events Request for Applications Research Research Personnel Research Project Grants Role Scientist Seasons Senior Scientist Series Signal Transduction Social Interaction Specialist Therapeutic Thinking Time Tissues Translations Travel United States National Institutes of Health Work abstracting age group base cell type chemokine chemokine receptor empowered experience graduate student human disease innovation intercellular communication medical specialties meetings migration novel novel strategies peer planetary Atmosphere posters professor programs receptor research study symposium therapeutic target tumor

项目摘要

DESCRIPTION (provided by applicant): Chemokines, the structurally homologous, functionally distinct chemotactic cytokines together with their cognate classical and atypical receptors comprise a complex molecular network involved in nearly all aspects of human health and disease. The Gordon Research Conference (GRC) on Chemotactic Cytokines 2012 is a world premier meeting devoted entirely to understanding these important molecules. This will be our 10th Chemokine GRC, which has been held every other year since 1994, when chemokines first burst onto the scene as the largest cytokine gene family in the human genome. Similar to each preceding conference in this series, Chemokine GRC 2012 will bring together scientists from a broad range of biomedical disciplines to showcase the latest unpublished research findings that cover all aspects of chemokine function and provide a high-quality scientific forum to discuss their potential implications, including translation to the clinic. The program of this meeting will cover basic biochemical and biological aspects of chemokines as related to their contributions to leukocyte migration, emigration, immune tissue organization and function; the role of chemokines during inflammation, including infectious diseases and autoimmunity in distinct organs and tissues; and multifaceted contributions of chemokines to cancer pathogenesis. In addition, for the first time in the history of this conference, we will introduce he Gordon Research Seminars (GRS), a satellite meeting for bench scientists at the graduate and postdoctoral level. GRS will provide a forum where young researchers can present their work and receive feedback on their ongoing research projects from their peers and a selected panel of senior experts. GRS will promote grassroots level integration and networking within the field of chemokine research. We fully anticipate that the scientific discussions, research talks, poster sessions, and informal interactions between the participants of this conference will contribute to advancing our understanding of molecular mechanisms of chemokine involvement in disease pathogenesis. This will set the basis for the development of new collaborative projects leading to new discoveries and ultimately resulting in new therapies and approaches to treat debilitating human disease, including inflammatory and autoimmune diseases and cancer. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference on Chemotactic Cytokines and the Gordon Research Seminar will bring together chemokine scientists from a variety of biomedical disciplines at all levels of this endeavor, including established investigators, junior investigators, and future generations of chemokine researchers. Scientific presentations, discussions and poster sessions during this conference will expand our understanding of the mechanisms by which chemokines contribute to health and disease. It is anticipated that the collegial and cooperative atmosphere that has traditionally characterized these conferences will provide the perfect setting for the intellectual development, cross-fertilization and future collaborations that are so vital to keep this field at the forefront of scientific innovation and discovery.

描述（由申请人提供）：趋化因子是结构同源、功能不同的趋化细胞因子，与其同源经典和非典型受体一起构成了涉及人类健康和疾病的几乎所有方面的复杂分子网络。 2012 年戈登趋化细胞因子研究会议 (GRC) 是一次世界顶级会议，完全致力于了解这些重要分子。这将是我们的第十届趋化因子 GRC，自 1994 年以来，每两年举办一次，当时趋化因子作为人类基因组中最大的细胞因子基因家族首次崭露头角。与本系列之前的每次会议类似，Chemokine GRC 2012 将汇集来自广泛生物医学学科的科学家，展示涵盖趋化因子功能各个方面的最新未发表的研究成果，并提供一个高质量的科学论坛来讨论其潜在影响，包括到诊所的翻译。本次会议的议程将涵盖趋化因子的基本生化和生物学方面，以及它们对白细胞迁移、移出、免疫组织组织和功能的贡献；趋化因子在炎症过程中的作用，包括不同器官和组织中的传染病和自身免疫；以及趋化因子对癌症发病机制的多方面贡献。此外，我们将在本次会议历史上首次推出戈登研究研讨会（GRS），这是一个面向研究生和博士后水平的科学家的卫星会议。 GRS 将提供一个论坛，年轻的研究人员可以在其中展示他们的工作，并从同行和选定的高级专家小组那里获得关于他们正在进行的研究项目的反馈。 GRS 将促进趋化因子研究领域内的基层整合和网络化。我们完全期望本次会议参与者之间的科学讨论、研究报告、海报会议和非正式互动将有助于增进我们对趋化因子参与疾病发病机制的分子机制的理解。这将为开发新的合作项目奠定基础，从而带来新的发现，并最终产生治疗衰弱性人类疾病（包括炎症和自身免疫性疾病以及癌症）的新疗法和方法。公共健康相关性：戈登趋化细胞因子研究会议和戈登研究研讨会将汇集来自各个生物医学学科的趋化因子科学家，包括资深研究人员、初级研究人员和未来几代趋化因子研究人员。本次会议期间的科学演讲、讨论和海报会议将扩大我们对趋化因子促进健康和疾病的机制的理解。预计这些会议传统上的学院和合作氛围将为智力发展、交叉受精和未来合作提供完美的环境，这对于保持该领域处于科学创新和发现的前沿至关重要。