Systems Science Center for Musculoskeletal CAM Therapies

肌肉骨骼 CAM 治疗系统科学中心

• 批准号: 8731795
• 负责人: Jacek Cholewicki
• 金额: $ 98.46万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8731795
• 关键词: Address; Adverse effects; Affect; Award; Awareness; Clinical; Clinical Research; Communities; Devices; Disease; Engineering; Equilibrium; Event; Experimental Designs; Faculty; Future; Genetic Crossing Over; Goals; Head and neck structure; Health Care Costs; Individual; Interdisciplinary Study; Intervention; Leadership; Low Back Pain; Measures; Mentors; Michigan; Motor; Musculoskeletal; Musculoskeletal Equilibrium; Musculoskeletal System; Neck Pain; Nursing Faculty; Osteopathic Medicine; Osteopathic manipulation; Outcome Measure; Patients; Performance; Positioning Attribute; Research; Research Project Grants; Research Training; Resources; Robot; Science; Sensory; Speed; Spinal; Students; System; Therapeutic Studies; Time; United States National Institutes of Health; Universities; base; college; instrument; motor control; multidisciplinary; neuromuscular; neuromusculoskeletal; programs; response; tool

The overall goal of this PCCTR is to address three major barriers to increase capacity for CAM research at Michigan State University College of Osteopathic Medicine (MSUCOM): 1) the lack of standardized, objective instruments and measures for characterizing and optimizing osteopathic manipulative therapy (OMT) interventions, 2) the lack of visible ongoing OMT research programs and 3) the lack of research training of clinical faculty. The rationale for the three research projects is based on the overall hypothesis that OMT affects some aspects of sensory and/or motor functions of the musculoskeletal system. Thus, improvement in performance of such a system should serve as an objective outcome measure. In project one, a systems science approach will be applied to identify deficits in postural control of individuals with low back pain (LBP) and assess the effects of OMT on postural control. A parallel robot device, programmed to mimic unstable sitting on a half-cylinder, will be used to quantify balance and postural control before and after 4 weeks of OMT in a cross-over experimental design. Project two will investigate whether OMT can mitigate adverse effects from a sudden, unexpected trunk perturbation by resulting in a faster and more accurate response of the postural control system to such an event in patients in LBP. The speed of the control system and its accuracy will be quantified before and after 4 weeks of OMT in a cross-over experimental design. Project three will develop clinical research tools for the assessment of motor control of the head-neck system. Using a cross-over experimental design, these tools will then be applied to measure changes in position and force control of the head-neck system in patients with and without neck pain before and after 4 weeks of OMT.

本次 PCCTR 的总体目标是解决提高密歇根州立大学整骨医学学院 (MSUCOM) CAM 研究能力的三大障碍：1) 缺乏标准化、客观的仪器和措施来表征和优化整骨手法治疗 (OMT) ) 干预措施，2) 缺乏明显的正在进行的 OMT 研究项目，3) 缺乏临床教师的研究培训。 这三个研究项目的基本原理是基于 OMT 影响肌肉骨骼系统的感觉和/或运动功能的某些方面的总体假设。 因此，此类系统性能的改进应作为客观结果衡量标准。 在项目一中，将应用系统科学方法来识别腰痛 (LBP) 患者的姿势控制缺陷，并评估 OMT 对姿势控制的影响。 并行机器人装置被编程为模拟半圆柱体上不稳定的坐姿，将用于在交叉实验设计中量化 4 周 OMT 前后的平衡和姿势控制。 项目二将研究 OMT 是否可以通过使姿势控制系统对 LBP 患者的此类事件做出更快、更准确的反应来减轻突然、意外的躯干扰动带来的不利影响。 在交叉实验设计中，控制系统的速度及其准确性将在 4 周的 OMT 前后进行量化。 项目三将开发用于评估头颈系统运动控制的临床研究工具。 使用交叉实验设计，这些工具将用于测量 OMT 4 周之前和之后有和没有颈部疼痛的患者头颈系统的位置和力控制的变化。