1Florida Alzheimer's Disease Research Center Administrative Core

1佛罗里达阿尔茨海默病研究中心行政核心

• 批准号: 9921602
• 负责人: Todd E Golde
• 金额: $ 54.78万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9921602
• 关键词: African American; Alzheimer' s Disease; Alzheimer' s disease related dementia; Amyloid; Appointment; Autopsy; Award; Brain; Budgets; Clinical; Clinical Sciences; Collaborations; Complex; Consensus; Consent; Development; Disease; Doctor of Philosophy; Education; Educational Activities; Ensure; Extramural Activities; Fellowship; Florida; Foundations; Funding; Funding Mechanisms; Generations; Goals; Grant; Hispanic Americans; Human Resources; Infrastructure; Institutes; Institution; Leadership; Letters; Link; Longitudinal Studies; Pamphlets; Pathologic; Population Heterogeneity; Positioning Attribute; Positron-Emission Tomography; Privatization; Process; Publications; Request for Applications; Research; Research Activity; Research Personnel; Research Support; Resources; Science; Scientist; Site; Source; Structure; Training; Training and Education; Translational Research; Vision; Work; base; cohort; data management; data sharing; design; diverse data; education research; experience; interest; meetings; programs; ranpirnase; success; symposium; web site

As a funded P50 center, the current 1Florida ADRC administrative core has successfully managed the complex multi-institution collaborations vital to our success. We have also garnered the additional resources and funds needed to accomplish our infrastructure generating and scientific goals (e.g., funds for additional pilot proposals, ~300 amyloid PET scans, fellowship support, and data management support) We are adapting our administrative core structure and personnel to be responsive to the change in funding mechanism, grant structure, and programmatic goals. These alterations are designed to support i) the highly synergistic interactions between all the collaborating institutes, ii) an increased emphasis on education and training, iii) inclusion of developmental projects, and iv) expansions of clinical core activities to include cohorts at UF and UM. Of particular note, our expanded leadership group positions the 1Florida ADRC well within our institutions to expand Alzheimer ’s disease (AD) and Alzheimer’s related dementias (AD+ADRD) research activities. This leadership group also provides a breadth of AD+ADRD reaserch experience and reflects the broad foci of AD+ADRD research across our institutions. Four Aims are proposed: Aim 1: Provide the vision, infrastructure, oversight, and overall compliance needed to function as an effective multi-site ADRC. The Administrative core will coordinate center activities across institutions and track progress towards goals in a milestone driven fashion. Aim 2. Manage the request for applications, review and award of developmental projects. Aim 3. Promote AD+ADRD research and educational activities among our collaborating institutions and throughout the state. Aim 4. Actively leverage resources from our collaborating institutions, the State, and other stakeholders to advance AD+ADRD research.

作为一个受资助的 P50 中心，当前的 1 佛罗里达 ADRC 行政核心已成功 管理对我们的成功至关重要的复杂的多机构合作。 完成我们的基础设施建设和建设所需的额外资源和资金 科学目标（例如，额外试点提案的资金、约 300 次淀粉样蛋白 PET 扫描、奖学金 支持和数据管理支持）我们正在调整我们的管理核心结构和 人员对资助机制、赠款结构和 这些改变旨在支持 i) 高度协同。 所有合作机构之间的互动，ii) 更加重视教育和 培训，iii) 纳入发展项目，以及 iv) 将临床核心活动扩展到 包括佛罗里达大学和密西根大学的团队，特别值得注意的是，我们扩大的领导团队定位了 1佛罗里达州 ADRC 在我们的机构内开展工作，以扩大阿尔茨海默病 (AD) 和阿尔茨海默病的范围 该领导小组还提供了广泛的痴呆症（AD+ADRD）研究活动。 的 AD+ADRD 研究经验，反映了我们整个 AD+ADRD 研究的广泛重点 提出了四个目标： 目标 1：提供愿景、基础设施、监督和支持。 作为有效的多站点 ADRC 管理核心，需要整体合规性。 将协调各机构的中心活动并跟踪里程碑目标的进展情况 目标 2. 管理发展项目的申请、审查和授予请求。 目标 3. 在我们的合作中促进 AD+ADRD 研究和教育活动。 目标 4. 积极利用我们合作的资源。 机构、国家和其他利益相关者推进 AD+ADRD 研究。