NRSA Training Core

NRSA 培训核心

• 批准号: 9916832
• 负责人: Thomas Michel
• 金额: $ 67.03万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9916832
• 关键词: Active Learning; Basic Science; Bioinformatics; Biological; Biological Sciences; Biology; Biomedical Research; Boston; Chemicals; Chemistry; Clinical; Clinical Medicine; Clinical Sciences; Communities; Complement; Diagnosis; Discipline; Disease; Doctor of Philosophy; Educational Curriculum; Faculty; Foundations; Funding; Future; Goals; Human Biology; Immunology; Infrastructure; Leadership; Mentors; Methodology; Methods; National Research Service Awards; Neurosciences; Patients; Physicians; Prevention; Research; Science; Students; Systems Biology; TNFSF15 gene; Time; Training; Training Programs; Training Support; Translational Research; Translations; Universities; Workforce Development; base; career; catalyst; experience; graduate student; human disease; learning strategy; programs; translational medicine

The Harvard Catalyst (HC) TL1 Training Program provides the organizational, curricular, and intellectual infrastructure for creating and mentoring a community of students and faculty engaged in disease-oriented research and the translation of principles of human biology to clinical medicine. TL1 offers an interdisciplinary PhD program that integrates human biology and translational medicine training for graduate students in life sciences graduate programs across Harvard University (HU). For the past nine years, the TL1 Program has provided a cornerstone of support for some of the best graduate students in the Leder Human Biology Program (LHB Program). TL1 currently supports 39 students, integrated in the larger community of 78 students in the LHB program. Students in the TL1 program come from graduate programs across Harvard University, including Biological and Biomedical Sciences, Neurosciences, Immunology, Systems Biology, and Chemistry and Chemical Biology. The two TL1 Co-Leads, Connie Cepko, PhD, and Thomas Michel, MD, PhD, have extensive and complementary expertise in basic, translational, and clinical science, and longstanding experience in the leadership of graduate training programs. Going forward, TL1 will continue to represent a key component of the HC Translational Workforce Development (see Core D. Translational Endeavors). TL1 will expand to incorporate new training programs in team science, quantitative methods, and bioinformatics that complement current programs to prepare an effective biomedical research workforce of the future. Each year TL1 will select seven new first-year graduate students. The average time to obtaining the PhD degree for TL1 students is 5.7 years. Awardees will be supported for the first two years of their PhD studies, after which support will come from their PhD mentors' research program, or from institutional funds or foundations. The objectives of the TL1 Training Core are to: (Aim 1) Provide a graduate curriculum with a focus on quantitative team-based active learning methods that will train graduate students in the mechanisms and methodologies of human biology and disease-oriented T0/T1 discovery, and provide them with direct clinical contact with patients and physicians; (Aim 2) Establish a context for human disease-oriented translational research in paracurricular activities across HC that connect clinical medicine with student research in human biology and translational medicine; and (Aim 3) Nurture a diverse community of students and faculty with shared goals of applying rigorous methodologies to the translation of basic discoveries to prevention, diagnosis, and treatment of human disease, while also reaching out into the broader Boston community. TL1 will select and support the training of the best graduate students committed to careers in human biology and translational medicine, and who will benefit from and contribute to the discipline at HU and beyond.

哈佛大学催化剂（HC）TL1培训计划提供了组织，课程和知识分子 用于创建和指导一个学生和教职员工的基础设施 研究和人类生物学原理向临床医学的翻译。 TL1提供跨学科 博士计划，将人类生物学和翻译医学培训整合到生活中的研究生 哈佛大学（HU）的科学研究生课程。在过去的九年中，TL1计划有 为LEDER人类生物学计划中的一些最好的研究生提供了支持的基石 （LHB程序）。 TL1目前支持39名学生，并集成了78名学生的较大社区 LHB程序。 TL1课程的学生来自哈佛大学的研究生课程 包括生物学和生物医学科学，神经科学，免疫学，系统生物学和化学 和化学生物学。两位TL1共同领导者Connie Cepko，PhD和医学博士的Thomas Michel 基础，翻译和临床科学领域的广泛和互补专业知识以及长期 在研究生培训计划的领导方面经验。 展望未来，TL1将继续代表HC Translations Workerfer的关键组成部分 开发（请参阅Core D.转化工作）。 TL1将扩展以将新的培训计划纳入 团队科学，定量方法和生物信息学补充当前计划以准备 未来的有效生物医学研究人员。每年TL1都会选择七个新的一年级毕业生 学生。获得TL1学生博士学位的平均时间为5。7年。获奖者将是 在其博士学位研究的前两年得到了支持，此后将获得博士学位导师的支持 研究计划，或机构基金或基金会。 TL1培训核心的目标是：（ AIM 1）提供研究生课程，重点是 基于定量团队的积极学习方法将培训研究生的机制和 人类生物学和面向疾病的T0/T1发现方法，并为其提供直接的临床 与患者和医生接触； （AIM 2）为面向人类疾病的翻译建立背景 跨HC的校友活动的研究，将临床医学与学生研究联系起来 生物学和翻译医学； （目标3）培养一个多元化的学生和教职员工 将严格的方法论应用于将基本发现转化为预防的共同目标， 诊断和治疗人类疾病，同时也进入了更广泛的波士顿社区。 TL1将选择并支持致力于人类生物学职业的最佳研究生的培训 和转化医学，谁将受益于HU及其他地区的学科。