2020 Basal Ganglia Gordon Research Conference and Gordon Research Seminar

2020基底节戈登研究大会暨戈登研究研讨会

基本信息

批准号：
9912902
负责人：
Rui M. Costa
金额：
$ 1.5万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-01-01 至 2022-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9912902
关键词：
Address Basal Ganglia Basic Science Brain Brain region Child Care Clinic Clinical Clinical Research Cognition Collaborations Communities Computer Models Country Decision Making Development Disease Dystonia Education Equilibrium Event Evolution Freezing Functional disorder Gait Gender Gilles de la Tourette syndrome Goals Health Hearing Hour Huntington Disease International Leadership Link Mentors Minority Mission Modeling Motivation Movement Obsessive-Compulsive Disorder Parkinson Disease Participant Postdoctoral Fellow Psychomotor Disorders Research Research Personnel Resources Role Scientist Societies Structure Students Thinking Time Translations Travel Underrepresented Minority United States National Institutes of Health Woman Work addiction base career clinically relevant collaborative environment design human disease innovation interest knowledge translation lectures meetings next generation posters pre-doctoral programs social symposium tool unpublished works

项目摘要

Project Summary/Abstract: The basal ganglia are an intricately interconnected group of subcortical brain regions that are critical for the motivation, selection, initiation, and execution of actions. Consistent with these roles, basal ganglia dysfunction is linked to debilitating psychomotor disorders, including Parkinson’s disease, Huntington’s disease, dystonia, addiction, obsessive compulsive disorder, and Tourette’s syndrome. The importance of the basal ganglia in health and disease, together with the on-going development and evolution of approaches to probe their roles and interactions, have motivated diverse research communities focused on these structures. Despite growing interest in basal ganglia research, before the inaugural Basal Ganglia Gordon Research Conference (GRC) in 2014, the only conference focused on the basal ganglia was the triennial meeting of the International Basal Ganglia Society (IBAGS), which is usually held outside the USA. Moreover, IBAGS meetings follow a typical symposium format, which contrasts markedly with the interactive, discussion-oriented format of a GRC. Since 2016, the Basal Ganglia GRC has incorporated a 1.5 day Gordon Research Seminar (GRS) organized exclusively by and for pre- and post-doctoral trainees. Beginning with the 2018 Basal Ganglia GRC & GRS, these are now regular biennial meetings. The programs for the 2020 Basal Ganglia GRC & GRS were designed by an interdisciplinary committee representing basic and clinical research in the field. A deliberate effort was made to include new speakers and topics that were not included in the 2018 meeting, with the overarching theme Basal Ganglia: From Thought to Action. Topics include cognition and decision making, cellular plasticity in the basal ganglia, interactions within and beyond basal ganglia circuits, new computational models, and clinically relevant freezing of gait. The 2020 Basal Ganglia GRC and GRS have 3 specific aims: 1) move basal ganglia research forward by featuring cutting-edge research in an interactive environment that encourages questions and discussion, challenges current thinking, identifies open questions, and provides opportunities new collaborations; 2) model diversity in basal ganglia research with respect to scientific approach and topics, gender balance, career stage, and minority representation; and 3) provide opportunities for leadership, education, and mentoring for early career scientists. Successful completion of these aims will advance basal ganglia research by encouraging new ideas and collaborations, highlighting diversity in the field, and inspiring the next generation of scientists. This should accelerate the pace of discovery and translation to the clinic, consistent with the mission of NIH.

项目摘要/摘要：基底神经节是一组错综复杂、相互关联的皮层下大脑区域，对于大脑的正常运转至关重要。与这些角色一致的动作的动机、选择、启动和执行。与衰弱性精神运动障碍有关，包括帕金森病、亨廷顿病、肌张力障碍、成瘾、强迫症和抽动秽语症。基底神经节在疾病中的重要性。健康和疾病，以及探索其作用的方法的不断发展和演变和相互作用，激励了不同的研究团体关注这些结构，尽管这些结构不断增长。在首届基底神经节戈登研究会议 (GRC) 之前，对基底神经节研究产生了兴趣 2014年，唯一关注基底神经节的会议是每三年一次的国际基底神经节会议 Ganglia Society (IBAGS)，通常在美国境外举行。研讨会形式，与 GRC 的互动式、以讨论为导向的形式形成鲜明对比。 2016年，Basal Ganglia GRC合并举办了为期1.5天的戈登研究研讨会（GRS）从 2018 年基底神经节 GRC 和 GRS 开始，专供博士前和博士后学员使用。这些现在是每两年一次的定期会议，2020 年基底神经节 GRC 和 GRS 的计划是。由代表该领域基础和临床研究的跨学科委员会设计。努力纳入 2018 年会议中未包括的新发言者和主题，总体主题基底神经节：从思想到行动主题包括认知和决策，基底神经节的细胞可塑性、基底神经节回路内外的相互作用、新的计算模型和临床相关的步态冻结。 2020 年基底神经节 GRC 和 GRS 有 3 个具体目标：1）通过以下方式推动基底神经节研究向前发展：在鼓励提问和讨论的互动环境中进行尖端研究，挑战当前的思维，确定开放性问题，并提供新的合作机会 2) 模型；基底神经节研究在科学方法和主题、性别平衡、职业阶段、和少数族裔代表；3) 为早期教育提供领导、教育和指导的机会成功完成这些目标将通过鼓励促进基底神经节研究。新想法和合作，突出该领域的多样性，并激励下一代科学家。这应该会加快发现和转化为临床的步伐，这与 NIH 的使命是一致的。