A Pragmatic Clinical Trial of MyPEEPS Mobile to Improve HIV prevention Behaviors in Diverse Adolescent MSM

MyPEEPS Mobile 改善不同青少年 MSM 的 HIV 预防行为的实用临床试验

基本信息

批准号：
9902191
负责人：
Robert Garofalo
金额：
$ 157.58万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-09-01 至 2022-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9902191
关键词：
18 year old AIDS prevention AIDS/HIV problem Address Adolescent Affect Age Alcohols Anus Behavior Behavior Therapy Behavioral Car Phone Caricatures Cellular Phone Chicago Computers Devices Educational Curriculum Ensure Ethnic group Evidence based intervention FDA approved Family Frequencies Geography Goals HIV HIV Infections HIV Seronegativity HIV/STD Health Incidence Individual Intervention Knowledge Latino Level of Evidence Life Link Literature Minority Groups Nature New York City Online Systems Oral Oral Sex Participant Patient Self-Report Personal Communication Persons Pharmaceutical Preparations Population Population Group Populations at Risk Pragmatic clinical trial Preventive Intervention Privacy Prophylactic treatment Public Health Randomized Randomized Controlled Trials Reporting Research Risk Safe Sex Sampling Schedule Self Efficacy Sexual Health Sexual Partners Site Structure Tablets Testing Time Translating Translations Travel Unsafe Sex Update Ursidae Family Work adolescent men who have sex with men age group aged base condomless anal sex condoms cost design efficacy testing ethnic diversity ethnic minority population evidence base experience group intervention high risk high risk sexual behavior improved mHealth male member men who have sex with men mobile computing multi-site trial novel pilot trial portability pre-exposure prophylaxis primary outcome racial and ethnic racial diversity racial minority response scale up sexual risk behavior skills social theories user centered design web-enabled young men who have sex with men

项目摘要

PROJECT SUMMARY Men who have sex with men (MSM) bear a greater burden of HIV/AIDS than any other population group in the US, comprising only 2% of the population but 56% of individuals living with HIV/AIDS. Although much of the increased incidence in HIV has been reported among young MSM (YMSM), especially among racial and ethnic minority groups, and is linked to high-risk sexual behavior, there remains a dearth of evidence-based HIV prevention interventions for YMSM – and none that address racially/ethnically diverse YMSM. To address this need, our study, in response to RFA-MD-15-012, leverages mobile technology and MyPEEPS, an existing theory-driven, multi-ethnic, group-level, evidence-based intervention for diverse YMSM. MyPEEPS is a manualized curriculum, developed by members of our proposed Investigative team, comprised of 6 modules focusing on key intermediate social and personal factors, including knowledge (e.g., correct way to use a condom), self-efficacy for safer sex, interpersonal communication skills and behavioral skills. MyPEEPS is one of the only HIV prevention interventions in the literature that focuses on diverse adolescent MSM. Long-term sustainability of face-to face, group-level behavioral interventions, such as MyPEEPS, have been problematic for dissemination in at-risk populations, particularly among young racial and ethnic minority groups. In response to this challenge, we propose to translate MyPEEPS from a face-to-face, group-based curriculum to a mobile, responsive-driven web-based platform, accessible by smartphone or other web-enabled devices, to increase accessibility and scalability for diverse YMSM. The ubiquitous nature of mobile phones in daily life, especially among 13-18 year olds, has created opportunities for health interventions in a portable format with enhanced privacy. Using a participatory approach, our study will incorporate user-centered design in the translation of the MyPEEPS intervention onto a mobile platform. MyPEEPS Mobile will be tested in an RCT with racially and ethnically diverse HIV-negative or unknown status YMSM aged 13-18 at four geographically diverse sites: Birmingham, Chicago, New York City, and Seattle, allowing for increased generalizability of findings. The proposed MyPEEPS Mobile intervention is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information specifically developed for at-risk YMSM. This will be the one of the first studies to test the efficacy of a scaled-up, mobile version of an existing HIV prevention intervention originally developed for, designed by, and piloted for, a diverse group of YMSM. The research team has unique experience and expertise to conduct this important work and has conducted significant preliminary work related to the project goals. If efficacious, the public health impact is large, as the intervention will already be in mobile format which is well-suited for widespread dissemination.

项目概要男男性行为者 (MSM) 比该地区任何其他人口群体承受着更大的艾滋病毒/艾滋病负担美国仅占人口的 2%，但 56% 的人患有艾滋病毒/艾滋病。虽然大部分据报道，年轻 MSM (YMSM) 的艾滋病毒发病率有所增加，特别是在种族和族裔中少数群体，并且与高风险性行为有关，但仍然缺乏基于证据的艾滋病毒 YMSM 的预防干预措施——但没有解决种族/民族多元化的 YMSM 问题。需要，我们的研究响应 RFA-MD-15-012，利用移动技术和 MyPEEPS（现有的理论驱动的、多种族的、群体层面的、基于证据的多元化 YMSM 干预措施是一种针对不同 YMSM 的干预措施。手动课程，由我们提议的调查团队成员开发，由 6 个模块组成关注关键的中间社会和个人因素，包括知识（例如，使用安全套）、安全性行为的自我效能、人际沟通技巧和行为技巧就是其中之一。文献中唯一关注不同青少年 MSM 的艾滋病毒预防干预措施。面对面、群体层面的行为干预措施（例如 MyPEEPS）的可持续性一直存在问题向高危人群传播，特别是在年轻的种族和少数民族群体中。为了应对这一挑战，我们建议将 MyPEEPS 从面对面的、基于小组的课程转变为一个移动的、响应式驱动的网络平台，可通过智能手机或其他网络设备访问，提高多样化 YMSM 的可访问性和可扩展性手机在日常生活中无处不在，特别是在 13-18 岁的人群中，创造了以便携式方式进行健康干预的机会使用参与式方法，我们的研究将以用户为中心的设计纳入其中。将 MyPEEPS 干预移植到移动平台上将在随机对照试验中进行测试。具有不同种族和民族的 HIV 阴性或身份不明的 YMSM，年龄 13-18 岁，地理分布四不同的地点：伯明翰、芝加哥、纽约市和西雅图，从而提高了拟议的 MyPEEPS 移动干预是一种新颖的、基于证据的移动干预。专为高危 YMSM 开发的提供艾滋病毒预防信息的技术。首批研究测试现有艾滋病毒预防干预措施的放大移动版本的功效最初是为 YMSM 的多元化群体开发、设计和试点的，该研究团队拥有独特的优势。开展这项重要工作的经验和专业知识，并已开展相关的重要前期工作如果有效，对公共健康的影响将是巨大的，因为干预措施已经在移动领域进行了。格式非常适合广泛传播。

项目成果

期刊论文数量（11）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Examining the Information Systems Success (ISS) of a mobile sexual health app (MyPEEPS Mobile) from the perspective of very young men who have sex with men (YMSM).

DOI：
10.1016/j.ijmedinf.2021.104529
发表时间：
2021-09
期刊：
International journal of medical informatics
影响因子：
4.9
作者：
Cordoba E;Idnay B;Garofalo R;Kuhns LM;Pearson C;Bruce J;Batey DS;Radix A;Belkind U;Hidalgo MA;Hirshfield S;Rodriguez RG;Schnall R
通讯作者：
Schnall R

Homonegative Victimization and Perceived Stress among Adolescent Sexual Minority Males: The Attenuating Role of Peer and Family Support.

青少年性少数男性的同性受害和感知压力：同伴和家庭支持的减弱作用。

DOI：
10.1080/19317611.2022.2124341
发表时间：
2022
期刊：
International journal of sexual health : official journal of the World Association for Sexual Health
影响因子：
0
作者：
Gordián-Arroyo,Alvin;Schnall,Rebecca;Garofalo,Robert;Kuhns,LisaM;Pearson,Cynthia;Bruce,Josh;ScottBatey,D;Radix,Asa;Belkind,Uri;Hirshfield,Sabina;Hidalgo,MarcoA
通讯作者：
Hidalgo,MarcoA

Preliminary Results from a Pragmatic Clinical Trial of MyPEEPS Mobile to Improve HIV Prevention Behaviors in Young Men.

DOI：
10.3233/shti200444
发表时间：
2020-06-16
期刊：
Studies in health technology and informatics
影响因子：
0
作者：
Schnall R;Kuhns L;Pearson C;Bruce J;Batey DS;Radix A;Belkind U;Hidalgo MA;Hirshfield S;Ganzhorn S;Garofalo R
通讯作者：
Garofalo R

Risk-taking behaviors in adolescent men who have sex with men (MSM): An association between homophobic victimization and alcohol consumption.

DOI：
10.1371/journal.pone.0260083
发表时间：
2021
期刊：
PloS one
影响因子：
3.7
作者：
Cordoba E;Garofalo R;Kuhns LM;Pearson C;Bruce J;Batey DS;Radix A;Belkind U;Hidalgo MA;Hirshfield S;Garibay Rodriguez R;Schnall R
通讯作者：
Schnall R

A Mobile Health Intervention for HIV Prevention Among Racially and Ethnically Diverse Young Men: Usability Evaluation.