Development and Testing of MyPEEPS Mobile for Young Transgender Men

为年轻跨性别男性开发和测试 MyPEEPS Mobile

• 批准号: 10407736
• 负责人: Robert Garofalo
• 金额: $ 34.15万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-01 至 2024-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10407736
• 关键词: 18 year old; 19 year old; AIDS prevention; Address; Adolescent and Young Adult; Behavior; Behavior Therapy; Behavioral; Birth; Caricatures; Clinical; Cohort Studies; Data; Development; Enabling Factors; Epidemiology; Face; Family; Feedback; Female; Focus Groups; Future; Gender Identity; Goals; HIV; HIV Infections; Health; High Prevalence; Human immunodeficiency virus test; Individual; Intervention; Interview; Literature; Mechanics; Methodology; Methods; New York City; Population; Predisposing Factor; Prevalence; Prevention; Prevention program; Principal Investigator; Public Health; Randomized Controlled Trials; Reinforcing Factor; Reporting; Research; Risk; Risk Behaviors; Sampling; Science; Sexual Health; Sexually Transmitted Diseases; Site; Testing; Time; United States; Work; Youth; base; cis-male; cisgender; condomless anal sex; efficacy study; efficacy trial; experience; feasibility testing; health care service; health outcome disparity; high risk; high risk behavior; improved; interest; mHealth; male; minority children; mobile application; mobile computing; multidisciplinary; novel; peer; pre-exposure prophylaxis; preventive intervention; response; scale up; sex; sexual debut; sexual minority; sexual minority men; social; therapy design; transgender; transgender men; transgender women; uptake; usability; young men who have sex with men

PROJECT SUMMARY Transgender youth in the United States have unique health needs but often face barriers to accessing and receiving health care services which contribute to disparate health outcomes including high vulnerability to HIV and other sexually transmitted infections. Emerging evidence has begun to document HIV-related sexual risk among young transgender men (YTM), as well as low uptake of pre-exposure prophylaxis among those with indications, suggesting high vulnerability to HIV infection. Despite the high prevalence and increased risk of HIV in YTM who have sex with cisgender men, only one prior HIV prevention intervention has been developed to address the specific sexual health needs of YTM, which indicates a critical gap in HIV prevention science. In response to this need, and building off our strong preliminary work, we propose to develop a mobile intervention for YTM building on MyPEEPS Mobile, which was originally developed for very young sexual minority men. Central to this intervention is the premise that it will be delivered to youth during a developmental period that precedes or coincides with sexual debut, an important time for intervention, prior to or concurrent with initiation of high-risk behaviors. Given both the gap in HIV prevention science and the lack of current targeted interventions, and building upon our multidisciplinary team’s extensive experience in HIV prevention, mHealth, behavioral interventions, randomized controlled trials, and transgender health, we propose the following specific aims: 1) Using qualitative methodology, expert feedback, and usability assessments, develop MyPEEPS Mobile for YTM, 2) Conduct a pilot randomized controlled trial to examine the feasibility, acceptability, and preliminary efficacy of the revised MyPEEPS Mobile App in a sample of 80 YTM (15-19 years) and refine the study methods for a future efficacy trial, and 3) Assess predisposing, enabling, and reinforcing factors for MyPEEPS Mobile among YTM through theoretically-guided in-depth interviews. The proposed MyPEEPS intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information to high-risk youth. This will be the first study to develop and pilot a scaled- up, mobile HIV prevention intervention designed by, and piloted for, a diverse group of YTM. The final product of this study will be the basis for an R01 application to conduct a large-scale efficacy study for this population. The proposed MyPEEPS Mobile intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information specifically developed for YTM. Consequently, we are confident that the proposed intervention will be of high impact intervention for improving HIV prevention behaviors in YTM and have long-term implications for overall improvement in the public’s health.

项目摘要 美国的跨性别青年有独特的健康需求，但经常面临进入和 接受医疗服务，导致不同的健康成果，包括高艾滋病毒的脆弱性 和其他性传播感染。新兴证据已开始记录与HIV相关的性风险 在年轻的跨性别男性（YTM）中 适应症，表明艾滋病毒感染的高脆弱性。尽管患病率很高，而且风险增加了 与cisgender男性发生性关系的YTM的艾滋病毒，仅开发了一次预防艾滋病毒 解决YTM的特定性健康需求，这表明艾滋病毒预防科学的差距很大。在 对这种需求的响应，并在我们的强大初步工作中建立了我们建议开发手机 Mypeeps Mobile上的YTM建筑的干预措施，最初是针对非常年轻的性行为开发的 少数民族。这种干预的核心是前提是在发展期间将其交付给青年 与性首次亮相之前或同时发生的时期，这是干预的重要时间 启动高风险行为。鉴于艾滋病毒预防科学的差距和缺乏当前的差距 有针对性的干预措施，并基于我们多学科团队在艾滋病毒预防方面的丰富经验， MHealth，行为干预，随机对照试验并翻译健康，我们提出了 以下具体目的：1）使用定性方法，专家反馈和可用性评估，开发 ytm的mypeeps手机，2）进行一项试验随机对照试验，以检查可行性， 在80 ytm的样本中，修订后的mypeeps移动应用程序的可接受性和初步效率（15-19 年）并完善研究方法的未来效率试验，3）评估易感性，启用和 通过理论引导的深入访谈，在YTM中为mypeep移动的增强因素。这 YTM提出的MyPeeps干预是一种新颖的循证驱动干预措施，使用移动技术 向高风险青年提供艾滋病毒预防信息。这将是第一个开发和试行缩放的研究 UP，由YTM的潜水员群体设计并试行的移动艾滋病毒预防干预措施。最终产品 这项研究将是R01应用的基础，以对该人群进行大规模效率研究。 YTM提出的MyPeeps移动干预是一种新颖的循证驱动干预措施 提供专门为YTM开发的艾滋病毒预防信息的技术。因此，我们是 确信拟议的干预措施将是改善艾滋病毒预防的高影响干预措施 YTM的行为，对公众健康的整体改善具有长期影响。