Research Training in the Neuroscience of Aging

衰老神经科学研究培训

• 批准号: 9753825
• 负责人: Mark G Baxter
• 金额: $ 17.28万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9753825
• 关键词: Aging; Neurosciences; Research Training

 DESCRIPTION (provided by applicant): The proposed program on Research Training in the Neuroscience of Aging will provide predoctoral students in Neuroscience with an integrated training experience in the laboratories of nationally and internationally recognized faculty. The predoctoral training program builds on an exciting, translationally relevant curriculum taught in years one and two of graduate school that has been awarded NIH support through the Jointly Sponsored Predoctoral Early Stage T32 Training Program mechanism (T32 MH087004). The proposed new training program would be the first at Mount Sinai to focus specifically on the neuroscience of aging and age- related neurodegenerative disease (primarily Alzheimer's disease), complementing Mount Sinai's historical concentration and strength in research in these areas. Outstanding training faculty in the proposed program share common research interests in the mechanisms of brain function in health and disease, employing a diversity of experimental approaches and working at levels of analysis ranging from molecular neurobiology to human neuropsychology and neuroimaging. The training program specifically encourages participation of faculty mentors whose research grants directly focus on aging neuroscience research, while not excluding those whose research expertise is critically important for the interdisciplinary training we seek to impart. Through their course work, predoctoral trainees will have received a solid foundation in basic neurobiology and the pathophysiology of neurological and psychiatric disease, as well as biostatistics and the responsible conduct of research. Advanced coursework includes a seminar course on the biology of aging as well as focused elective courses in specific areas of neuroscience. Selection of a research mentor is made in a collaborative environment that actively promotes multidisciplinary, integrative research. Research training will also have a `work in progress' component, to foster important interdisciplinary interactions, hone presentation skills, and improve awareness of ethical issues. Using this approach, the program on Research Training in the Neuroscience of Aging will provide predoctoral students with the guidance and experimental tools, in the laboratories of our training faculty, to launch successful, productive, independent careers in aging research.

 描述（由申请人提供）：拟议的衰老神经科学研究培训计划将为神经科学博士前学生提供在国内和国际认可的教师实验室中的综合培训经验。该博士前培训计划建立在令人兴奋的、具有转化意义的基础上。研究生院第一年和第二年教授的课程已通过联合资助的博士前早期 T32 培训计划机制 (T32 MH087004) 获得 NIH 的支持。该培训计划将是西奈山第一个专门关注衰老和与年龄相关的神经退行性疾病（主要是阿尔茨海默病）的神经科学的培训计划，补充了西奈山在这些领域的历史集中和研究实力。共同的研究兴趣是健康和疾病中的大脑功能机制，采用多种实验方法，并在从分子神经生物学到人类神经心理学和神经影像学的分析层面上开展工作。该培训计划特别鼓励拥有研究资助的教师导师参与。直接关注衰老神经科学研究，同时不排除那些研究专业知识对于我们寻求传授的跨学科培训至关重要的人，通过他们的课程工作，博士前学员将在基础神经生物学以及神经和精神疾病的病理生理学方面获得坚实的基础。以及生物统计学和负责任的研究行为，包括衰老生物学研讨会课程以及神经科学特定领域的重点选修课程，研究是在积极促进导师的合作环境中进行的。研究培训还将包含“正在进行的工作”部分，以促进重要的跨学科互动、磨练演讲技巧并提高对道德问题的认识，老龄化神经科学研究培训计划将采用这种方法。在我们培训教师的实验室中为博士前学生提供指导和实验工具，以在衰老研究领域开展成功、富有成效、独立的职业生涯。