Chemistry and Mechanisms for Environmental Stress

环境压力的化学和机制

• 批准号: 8597820
• 负责人: Daniel C Liebler
• 金额: $ 1万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8597820
• 关键词: American; Award; Base Excision Repairs; Biocompatible Materials; Biology; Breathing; Carcinogenesis Mechanism; Chemicals; Chemistry; Disease; Education; Environmental Exposure; Environmental Health; Event; Exposure to; Feedback; Fostering; Funding; Future; Health; Human; Knowledge; Learning; Link; Metals; Mission; Motion; Nanotechnology; National Institute of Environmental Health Sciences; Paper; Participant; Pharmaceutical Preparations; Postdoctoral Fellow; Prevention; Process; Request for Applications; Research; Research Personnel; Role; Science; Scientist; Senior Scientist; Societies; Stress; Students; Systems Analysis; Technology; Toxic effect; Toxicology; Training; Translational Research; Travel; Work; austin; base; data integration; environmental agent; environmental chemical; experience; human disease; interdisciplinary approach; lectures; meetings; metabolomics; metal poisoning; nanotoxicology; posters; professor; programs; public health relevance; structural biology; symposium; tool

DESCRIPTION (provided by applicant): This application requests support for programming of the Division of Chemical Toxicology of the American Chemical Society (ACS) at its 246th National Meeting and Exposition in Indianapolis, IN from Sunday, September 8, 2013 to Wednesday, September 11, 2013. A unique feature of this ACS meeting is the broad theme of the national meeting, "Chemistry in Motion", which aligns highlighted events across the programming of all ACS divisions. The mission of the ACS Division of Chemical Toxicology is to promote the understanding of chemical mechanisms that contribute to disease processes and the toxicity of environmental agents, biomaterials, drugs and endogenous chemicals. The Division integrates work in chemistry, chemical biology, structural biology, toxicology, environmental health sciences and disease mechanisms. Three interrelated symposia are planned around the central theme "Chemistry and Mechanisms of Environmental Stress" and include invited talks by a diverse group of leading established and emerging scientists. The three symposia for which support is requested have especially strong relevance to the mission of the NIEHS. The first is entitled "Metabolomics in Toxicology" and highlights the implementation of global profiling technologies and data integration tools for systems analysis. The second is entitled "Chemistry and Biology of Metal Toxicity" and focuses on new mechanistic studies of metal-biomolecule interactions and their systemic effects. The third symposium session is entitled "Toxicology of Alternative Fuels" and focuses on inhalation toxicity mechanisms and carcinogenesis. A proffered paper session and a Young Investigators Symposium offer opportunities for young scientists in training to present their primary contributions and receive critical feedback from senior experts. Other highlights are a keynote lecture by Dr. Christopher Austin (Director of the National Center for Advancing Translational Sciences) and two high profile award symposia (the Founders Award and the Chemical Research in Toxicology Young Investigator Award). These sessions (supported by non-federal funds) will further enhance a strong overall program and provide diverse participants an outstanding representation of current work in the chemistry and biology of environmental exposures and disease.

描述（由申请人提供）：本申请请求支持美国化学会 (ACS) 化学毒理学部于 2013 年 9 月 8 日星期日至 9 月 11 日星期三在印第安纳州印第安纳波利斯举行的第 246 届全国会议和博览会上的规划，2013 年。本次 ACS 会议的一个独特之处是全国会议的广泛主题“动态化学”，它协调了所有 ACS 部门的重点活动。 ACS 化学毒理学部的使命是促进对导致疾病过程以及环境因素、生物材料、药物和内源性化学物质毒性的化学机制的理解。该部门整合了化学、化学生物学、结构生物学、毒理学、环境健康科学和疾病机制方面的工作。围绕“化学和环境压力机制”的中心主题计划举办三场相互关联的研讨会，其中包括由不同领域的知名和新兴科学家邀请的演讲。请求支持的三个研讨会与 NIEHS 的使命尤其密切相关。第一篇题为“毒理学中的代谢组学”，重点介绍了用于系统分析的全局分析技术和数据集成工具的实施。第二个题为“金属毒性的化学和生物学”，重点关注金属-生物分子相互作用及其系统效应的新机制研究。第三场研讨会的主题是“替代燃料毒理学”，重点讨论吸入毒性机制和致癌作用。提供的论文会议和青年研究者研讨会为年轻科学家提供了接受培训的机会，以展示他们的主要贡献并获得资深专家的重要反馈。其他亮点包括克里斯托弗·奥斯汀博士（国家转化科学促进中心主任）的主题演讲和两个备受瞩目的奖项研讨会（创始人奖和毒理学化学研究青年研究员奖）。这些会议（由非联邦基金支持）将进一步增强强大的整体计划，并为不同的参与者提供环境暴露和疾病的化学和生物学当前工作的杰出代表。