A LONGITUDINAL STUDY OF SUBSTANCE ABUSE AND HIV RISK AMONG ADULT LATINA MOTHER-DA

成年拉丁裔母亲药物滥用和艾滋病毒风险的纵向研究

• 批准号: 8428571
• 负责人: Mario R De La Rosa
• 金额: $ 33.36万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-03 至 2015-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8428571
• 关键词: AIDS prevention; AIDS/HIV problem; Accounting; Acculturation; Adolescent; Adopted; Adult; Affect; Age; Alcohol or Other Drugs use; American; Anger; Buffers; Censuses; Centers for Disease Control and Prevention (U.S.); Chronic stress; Communication; Communities; County; Criminal Justice; Cross-Sectional Studies; Data; Data Collection; Daughter; Development; Doctor of Philosophy; Dominican; Drug usage; Employment; Environment; Equilibrium; Exhibits; Funding; Goals; HIV; HIV risk; Health; Hispanics; Homelessness; Honduran; Illicit Drugs; Imprisonment; Incidence; Individual; Institution; Laboratories; Latina; Latino; Learning; Link; Literature; Longevity; Longitudinal Studies; Maintenance; Medical; Mental Health; Methodology; Methods; Mexican; Minority Groups; Modeling; Mothers; National Institute of Drug Abuse; Outcome; Participant; Pilot Projects; Population; Population Growth; Prevention; Prevention program; Prevention strategy; Process; Public Health; Puerto Rican; Religion and Spirituality; Reporting; Research; Research Design; Risk; Risk Behaviors; Role; Rosa; Sampling; Substance Use Disorder; Substance abuse problem; System; Teenagers; Testing; Time; Trust; United States; United States National Institutes of Health; United States Substance Abuse and Mental Health Services Administration; Variant; Woman; Work; aged; base; experience; follow-up; health disparity; innovation; intergenerational; intimate partner violence; longitudinal design; prevent; programs; psychologic; reduced substance use; social; socioeconomics; substance abuse prevention; success; theories; treatment program

DESCRIPTION (provided by the applicant): The HIV contraction rate for Latina women in the U.S. is six times the rate for non-Latina, White women. Latinas are suffering disparate negative consequences from substance use disorders, including intimate partner violence, incarceration, homelessness, and medical ailments. Our long-term goal is to reduce the incidence of HIV and substance abuse related health disparities among Latinas. The objective of this application, which is a significant step in pursuit of this goal, is to determine how substance use (both licit and illicit) and HIV risk behavior trajectories of a community-based sample of Latina mothers and daughters are influenced by changes in familial mechanisms (mother-daughter acoplamiento or attachment), cultural processes, and other social determinants of substance abuse and HIV risk behaviors over time. The study design involves four waves of data collection. Baseline data were collected in a cross-sectional pilot study of intergenerational drug use and HIV risk behaviors among Latina mothers and daughters funded by NIDA (R24DA014260, PI: Mario De La Rosa, Ph.D.). Three new longitudinal assessments are proposed to follow-up on baseline assessment. The first new follow-up assessment will be spaced approximately 5 years from the original study's baseline assessment. The remaining two follow-up assessments will occur 1 year from the preceding follow-up assessment. Our first aim is to determine the influence of cultural and social determinants on trajectories of change for substance use and HIV risk behaviors among a community-based sample of Latina mothers and daughters. The working hypothesis is that Latina mothers and daughters who experience (1) more acculturation to U.S. culture; (2) poorer socioeconomic conditions; (3) a loss of interpersonal supports; (4) less religious involvement; (5) involvement with the criminal justice system; (6) intimate partner violence; (7) greater employment, relationship, and/or residential related chronic stress; or (8) declining mental health and medical status since their baseline assessment will exhibit either an increase in or maintenance of high rates of substance use and HIV risk behaviors over the 7 year assessment time period. Our second aim is to determine the influence of mother-daughter attachment on trajectories of change for substance use and HIV risk behaviors. Latina mothers and daughters who either increase their levels of attachment or maintain consistently high levels of attachment will report reduced or consistently lower levels of substance use and HIV risk behaviors over a 7 year time period. Our third aim is to determine the moderating role of mother-daughter attachment on associations between experiences of detrimental social determinants and trajectories of change for substance use and HIV risk behaviors.

描述（由申请人提供）：美国拉丁裔女性的艾滋病毒感染率是非拉丁裔白人女性的六倍。拉丁裔正遭受药物滥用障碍带来的不同负面后果，包括亲密伴侣暴力、监禁、无家可归和医疗疾病。我们的长期目标是减少拉丁美洲人之间艾滋病毒和药物滥用相关的健康差异的发生率。该应用程序是实现这一目标的重要一步，其目的是确定基于社区的拉丁裔母女样本的药物使用（合法和非法）和艾滋病毒风险行为轨迹如何受到以下变化的影响：随着时间的推移，家庭机制（母女依恋或依恋）、文化进程以及药物滥用和艾滋病毒危险行为的其他社会决定因素。研究设计涉及四波数据收集。基线数据是在 NIDA 资助的拉丁裔母女代际吸毒和艾滋病毒风险行为横断面试点研究中收集的（R24DA014260，PI：Mario De La Rosa 博士）。建议进行三项新的纵向评估以跟进基线评估。第一次新的后续评估将与原始研究的基线评估相隔大约 5 年。其余两次后续评估将在上次后续评估一年后进行。我们的首要目标是确定文化和社会决定因素对拉丁裔母女社区样本中药物使用和艾滋病毒危险行为变化轨迹的影响。工作假设是，拉丁裔母亲和女儿经历（1）更多地适应美国文化； （二）社会经济条件较差； (3) 失去人际支持； (4) 宗教参与较少； (5) 参与刑事司法系统； (6) 亲密伴侣暴力； (7) 更大的就业、人际关系和/或居住相关的慢性压力； (8) 心理健康和医疗状况下降，因为他们的基线评估将显示在 7 年评估期间物质使用和艾滋病毒危险行为的高比率增加或维持。我们的第二个目标是确定母女依恋对物质使用和艾滋病毒危险行为变化轨迹的影响。拉丁裔母亲和女儿如果增加了依恋水平或始终保持较高的依恋水平，将报告在 7 年的时间内减少或持续降低药物使用和艾滋病毒危险行为的水平。我们的第三个目标是确定母女依恋对有害社会决定因素的经历与物质使用和艾滋病毒危险行为的变化轨迹之间的关联的调节作用。