2021 Mitochondria in Health and Disease Gordon Research Conference

2021 年线粒体健康与疾病戈登研究会议

• 批准号: 10236763
• 负责人: Nika N Danial
• 金额: $ 3.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-01 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10236763
• 关键词: Acceleration; Aging; Area; Awareness; Basic Science; Behavior; Biochemistry; Bioenergetics; Biogenesis; Biological; Biology; Cardiovascular Diseases; Categories; Cells; Collaborations; Communication; Communities; Development; Diabetes Mellitus; Disease; Environment; Fellowship; Female; Fertilization; Fostering; Functional disorder; Funding; Genetic; Genome; Goals; Health; Hour; Human; Inborn Errors of Metabolism; International; Investigation; Iron; Italy; Knowledge; Malignant Neoplasms; Medicine; Mentors; Metabolism; Minority; Mitochondria; Mitochondrial Diseases; Molecular; National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; Nerve Degeneration; Obesity; Organelles; Oxidation-Reduction; Participant; Pathology; Pathway interactions; Patients; Physiology; Postdoctoral Fellow; Productivity; Proteins; Proteome; Regulation; Renaissance; Request for Applications; Research; Research Personnel; Schedule; Science; Scientist; Series; Source; System; Time; Tissues; Training; Translational Research; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Woman; age related; career; career development; cost; diversity and inclusion; drug discovery; frontier; genome integrity; graduate student; interest; meetings; metabolome; multidisciplinary; multiple omics; novel; posters; programs; proteostasis; rapid growth; symposium; trafficking

PROJECT SUMMARY This application seeks partial funds to support the Gordon Research Conference (GRC) on Mitochondria in Health and Disease to be held August 8-13, 2021. This is the second in a new series of GRCs, which emerged from the growing awareness within the mitochondrial community of the need for a forum to capture and integrate a wide range of rapidly evolving areas of mitochondrial biology from the perspective of both basic and translational science. The GRC format is particularly suited for this forum because it provides a setting where cutting edge unpublished findings are presented in an inclusive environment that attracts experts across labs worldwide for a five-day conference. Time for discussions and networking are rigorously protected and encouraged in every scientific session and through free times in the afternoons. A setting where open discussion takes place encourages collaboration and is crucial to advancing the frontiers of mitochondrial science. In addition to accelerating mitochondrial research and promoting cross-disciplinary collaborations, the conference is committed to enhance visibility and participation of women scientists and minorities. As such, 44% of confirmed speakers and 44% of discussion leaders in the conference program are women. In addition, short talks from abstracts will be prioritized to feature research by early career scientists, trainees, women and minorities. Moreover, a GRC-sponsored Power Hour, which is an open communication forum, is scheduled early during the conference to discuss challenges surrounding diversity in science. Another conference objective is to train graduate students and postdocs in mitochondrial science and provide networking and informal mentoring opportunities to enrich their career development. The format of the 2021 conference consists of 9 scientific sessions each composed of 3 full talks and one short talk selected from abstracts, as well as 4 two-hour poster sessions. The scientific sessions will have an integrative focus on novel molecular, cellular and organismal aspects of mitochondrial bioenergetics and metabolism, redox regulation, genome integrity, protein biogenesis, and proteostasis, and mitochondria-based crosstalk mechanisms via carrier systems as well as interorganellar communications. Each session has a mixture of talks ranging from fundamental biologic mechanisms to physiology/pathophysiology. As such, the program includes highly diverse topics while featuring frontiers of knowledge gained from a broad range of approaches, experimental systems and tissue types, as well as investigation of multiple diseases involving alterations in mitochondrial function. The scientific sessions feature outstanding mitochondrial biologists ranging from established investigators to early career scientists whose cutting-edge research has had high impact in the fields of aging, cancer, diabetes and obesity, cardiovascular disease, neurodegeneration, and inborn errors of metabolism. Given the collective breadth of expertise and research interests within the mitochondrial community, we believe our program will catalyze productive cross-disciplinary interactions to propel the field forward.

项目概要 本申请寻求部分资金支持戈登线粒体研究会议（GRC） 健康与疾病将于 2021 年 8 月 8 日至 13 日举行。这是新系列 GRC 中的第二次， 线粒体界越来越意识到需要一个论坛来捕获和整合 从基础和研究的角度，线粒体生物学的一系列快速发展的领域 转化科学。 GRC 格式特别适合此论坛，因为它提供了一种设置 未发表的前沿研究结果在一个包容性的环境中呈现，吸引了各个实验室的专家 全球范围内举行为期五天的会议。讨论和交流的时间受到严格保护 在每次科学会议和下午的空闲时间都受到鼓励。开放讨论的环境 会议鼓励合作，对于推进线粒体科学的前沿至关重要。在 除了加速线粒体研究和促进跨学科合作外，会议 致力于提高女科学家和少数群体的知名度和参与度。因此，44% 的人确认 会议议程中的演讲者和讨论领导者中有 44% 是女性。此外，简短的谈话 摘要将优先展示早期职业科学家、实习生、妇女和少数族裔的研究成果。 此外，GRC 赞助的“Power Hour”是一个开放式交流论坛，将于展会期间提前安排。 会议讨论围绕科学多样性的挑战。会议的另一个目标是培训 线粒体科学的研究生和博士后，并提供网络和非正式指导 丰富他们职业发展的机会。 2021 年会议的形式包括 9 个科学会议，每个会议由 3 场完整演讲和 1 场学术会议组成 从摘要中选出的简短演讲，以及 4 个两小时的海报会议。科学会议将有一个 综合关注线粒体生物能量学的新分子、细胞和有机体方面 代谢、氧化还原调节、基因组完整性、蛋白质生物发生和蛋白质稳态以及基于线粒体的 通过载体系统以及细胞间通信的串扰机制。每个会话都有一个 从基本生物机制到生理学/病理生理学的各种讲座。因此， 课程包括高度多样化的主题，同时具有从广泛的知识领域获得的前沿知识 方法、实验系统和组织类型，以及涉及多种疾病的研究 线粒体功能的改变。科学会议由杰出的线粒体生物学家参加，范围包括 从知名研究人员到早期职业科学家，他们的尖端研究对科学界产生了重大影响 衰老、癌症、糖尿病和肥胖、心血管疾病、神经退行性疾病和先天性缺陷等领域 代谢。鉴于线粒体界内专业知识和研究兴趣的集体广度， 我们相信我们的计划将促进富有成效的跨学科互动，推动该领域向前发展。