Dissemination & Implementation (D&l) Methods Core

传播

• 批准号: 8847669
• 负责人: ENOLA K PROCTOR
• 金额: $ 13.11万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2017-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8847669
• 关键词: Adoption; Animal Model; Area; Cancer Control; Centers for Disease Control and Prevention (U.S.); Centers of Excellence in Cancer Communications Research; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communities; Consultations; Development; Diagnosis; Doctor of Philosophy; Equipment and supply inventories; Evaluation; Evidence based intervention; Faculty; Funding; Goals; Grant; Hour; Incubators; Individual; Institutes; Knowledge; Leadership; Link; Maintenance; Malignant Neoplasms; Malignant neoplasm of prostate; Measures; Mentors; Methods; Mission; Modeling; Movement; Neighborhoods; Nursing Faculty; Nutritional; Obesity; Outcome; Outcome Measure; Phase; Predisposition; Prevention Research; Prevention strategy; Process Measure; Public Health; Public Health Practice; Publications; Readiness; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Series; Strategic Planning; Surveys; System; Testing; Training; Translational Research; Treatment outcome; Visit; Work; cancer prevention; cancer therapy; clinical practice; effective intervention; energy balance; evidence base; experience; implementation research; interdisciplinary collaboration; intervention program; obesity prevention; population based; programs; social; tool; uptake

Core Summary To close the gap between scientific discovery and application of effective interventions in clinical practice and to broad population-based strategies for the prevention and control of cancer, the transfer of evidence-based findings must be made through strategic Dissemination and Implementation (D8il) efforts; a need also reflected throughout the NCI Strategic Plan for Leading the Nation. Specific knowledge and expertise regarding successful D&l is essential to this mission. The TREC D&l Methods Core will provide an incubator for advancing the movement of scientific findings from individual research projects along the clinical research continuum (i.e. T l . T2) and to broad population-based application in communities and neighborhoods. Additionally, the Core's transdisciplinary focus will emphasize D&l linkage across TREC projects and cores. These activities will support the application of knowledge and experience from the TRECs multilevel approach to advance both research and practice related to the interaction of energy balance, obesity and the prevention, diagnosis and treatment of cancer. For example, the core will work with Project 1 (Moley) to transfer lessons about transgenerational animal models of nutritional impact on cancer predisposition to infiuences being studied in Project 2 (Wolin) about energy balance and prostate cancer treatment outcomes and Project 4 (Hovman) to model obesity and cancer linking social determinants. The Core's overarching goal is to accelerate the scientific and public health impact of TREC research across multiple levels. To achieve this goal, specific aims are: Aim 1: To increase the D&l capacity of TREC research projects across transdisciplinary areas of WUSTL and the SCC through D&l research efforts; Aim 2: To identify specific approaches and tools to enhance the dissemination of transdisciplinary discoveries of WUSTL and SCC related to energy balance, obesity and cancer; and Aim 3: To apply effective strategies to disseminate and implement evidence-based discoveries from the TREC and transdisciplinary collaborations of WUSTL and SCC into clinical and public health practice. The Core will be led by Enola Proctor. PhD with collaboration of core faculty and broad direction from TREC Leadership and Administration and Internal and External Scientific Advisory Boards. The faculty leaders in this core have already demonstrated: 1) use of state-of-the-art methods in study design, implementation, and evaluation; 2) D&l research; and 3) effective management of large-scale projects. Metrics for evaluating the core: Key process measures will include the number of contacts per month, consultation hours per month, D&l research applications submitted, and trainings conducted. Impact measures will include the number of D&l publications in high impact venues, D&l grants funded, and projects using evidence-based strategies for cancer control. Longer-term outcome measures include the adoption and maintenance of evidence-based approaches to cancer control. Outcome indicators are not likely to be changed during the developmental phase of this core but the infrastructure will be put in place for later tracking of long-term measures.

核心总结 缩小科学发现与临床实践中有效干预措施的应用之间的差距 到广泛的基于人群的癌症预防和控制策略、基于证据的转移 调查结果必须通过战略传播和实施 (D8il) 努力得出；也反映了一个需要 贯穿 NCI 领导国家战略计划。有关的具体知识和专业知识 成功的 D&L 对于这一使命至关重要。 TREC D&l 方法核心将为 推动临床研究中各个研究项目的科学发现的发展 连续体（即 T1.T2）并在社区和邻里中广泛基于人口的应用。 此外，核心的跨学科重点将强调 TREC 项目和核心之间的 D&L 联系。 这些活动将支持 TREC 多层次方法的知识和经验的应用 推进与能量平衡、肥胖及其预防相互作用相关的研究和实践， 癌症的诊断和治疗。例如，核心将与项目1（Moley）合作传输经验教训 关于营养对癌症易感性影响的跨代动物模型 项目 2（Wolin）研究了能量平衡和前列腺癌治疗结果，项目 4 （霍夫曼）建立了将社会决定因素联系起来的肥胖和癌症模型。核心的总体目标是 加速 TREC 研究在多个层面上对科学和公共卫生的影响。为了实现这一目标 目标，具体目标是： 目标 1：提高跨学科 TREC 研究项目的 D&L 能力 通过 D&l 研究工作的 WUSTL 和 SCC 领域；目标 2：确定具体方法和工具，以加强 WUSTL 和 SCC 与能量平衡、肥胖和癌症相关的跨学科发现的传播；目标 3：应用有效的策略，将 TREC 以及 WUSTL 和 SCC 跨学科合作的循证发现传播和实施到临床和公共卫生实践中。核心团队将由 Enola Proctor 领导。在核心教员的合作下获得博士学位，并获得 TREC 领导和管理以及内部和外部科学顾问委员会的广泛指导。该核心的教师领导者已经证明：1）在研究设计、实施和评估中使用最先进的方法； 2）D&l研究； 3）大型项目的有效管理。评估核心的指标：关键流程指标将包括每月的联系次数、每月的咨询时间、提交的 D&L 研究申请以及进行的培训。影响措施将包括高影响力场所的 D&L 出版物数量、资助的 D&L 赠款以及使用基于证据的癌症控制策略的项目。长期结果衡量标准包括采用和维持基于证据的癌症控制方法。在该核心的开发阶段，结果指标不太可能改变，但基础设施将到位，以便以后跟踪长期目标 措施。