2nd International Symposium on Collaterals to the Brain

第二届脑络国际研讨会

基本信息

批准号：
8785972
负责人：
DAVID SIGMUND LIEBESKIND
金额：
$ 1.5万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-08-15 至 2015-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8785972
关键词：
Academia Acute Address Adult Area Attention Basic Science Blood flow Brain Brain Diseases Cerebrovascular Circulation Cerebrum Chronic Clinical Clinical Research Clinical Trials Collaborations Collateral Circulation Consensus Development Diagnosis Disabled Persons Disease Engineering Environment Evaluation Event Fertilization Functional disorder Funding Future Goals Health Hour Image Infarction Influentials International Intracranial Atheroscleroses Journals Knowledge Measurable Mentors Minority Modeling Motivation National Institute of Neurological Disorders and Stroke Outcome Palpable Paper Participant Perfusion Plant Roots Play Postdoctoral Fellow Prevention Progress Review Group Public Health Publications Publishing Questionnaires Recovery Reperfusion Injury Request for Proposals Research Research Personnel Research Priority Resolution Risk Role Scholarship Science Scientist Series Specialist Stroke Structure Students Systems Biology Therapeutic Translational Research Travel Triage United States National Institutes of Health Woman Work acute stroke base career clinical practice disability hemodynamics improved industry partner innovation meetings multidisciplinary next generation novel outcome forecast parity programs restorative treatment stroke therapy success symposium treatment strategy

项目摘要

DESCRIPTION (provided by applicant): The 2nd International Symposium on Collaterals to the Brain is a multidisciplinary scientific conference focused on collateral perfusion in acute and chronic neurovascular disorders. This proposal requests partial support for a conference with broad, long-term objectives that will advance current research on collateral perfusion, identify gaps and produce a consensus statement on critical topics related to collaterals in stroke. Mentoring junior investigators in this endeavor is a major emphasis of this unique meeting devoted to collaterals to the brain. Collateral perfusion of the brain is now recognized as a fundamental determinant of stroke risk, ischemic infarction, and reperfusion injury including hemorrhagic transformation, recovery and clinical outcome in virtually every acute and chronic ischemic disorder of the brain. This forum has been established to devote attention to this top research priority of NINDS. The aims of this conference will convene over 48 leading experts to debate critical aspects of this burgeoning field, with a total of 400 participants for a 2-day conference in an academic setting. The confirmed program is structured into 12 one-hour debate topics on reverse engineering collaterals, endorsing a systems biology approach. Public forum debate format will be utilized by teams of 2 experts to methodically reach consensus, culminating with publication of a detailed consensus statement on research in collateral perfusion. A moderated dinner seminar on reverse mentoring will reflect upon the 6 themes addressed throughout the symposium, covered by 6 junior investigators nominated for travel scholarships. Every effort will be made to encourage participation by postgraduate students and postdocs, to have parity in the numbers of women, and to include minorities and persons with disabilities. Measurable outcomes of conference goals will be assessed, evaluating the impact of this symposium on the NIH commitment to new investigators, translational stroke research and the NINDS PRG priority for studies on collateral perfusion. The significance of this proposal is underscored by the cultivation of a framework for novel research collaborations, mentoring of new investigators and improved clinical practice in this area, through a unique event, associated interactions and subsequent publication of a consensus statement. The health relatedness of this proposal is rooted in the discussions and research initiatives that address key priorities on the influential role of collaterals in the devastating disorder of stroke.

描述（由申请人提供）：第二届国际大脑抵押品研讨会是一次多学科科学会议，重点是急性和慢性神经血管疾病。该提案要求为一次会议提供部分支持，该会议具有广泛的长期目标，该会议将推进有关侧支灌注的当前研究，识别差距并就与中风中的抵押品相关的关键主题提出共识声明。在这项工作中指导初级调查人员是这次专门致力于大脑的独特会议的主要重点。现在，大脑的附带灌注被认为是中风风险，缺血性梗塞和再灌注损伤的基本决定因素，包括大脑的每种急性和慢性缺血性疾病，包括出血转化，恢复和临床结果。该论坛的建立是为了关注Ninds的这一主要研究优先事项。这次会议的目标将召集超过48位领先的专家来辩论这个新兴领域的关键方面，共有400名参与者参加了在学术环境中为期2天的会议。确认的计划成立于12个为期一小时的辩论主题，以认可系统生物学方法。公共论坛辩论格式将由2名专家组成的团队有条不紊地达成共识，最终发表有关附带灌注研究的详细共识声明。关于反向指导的主持晚餐研讨会将反映在整个研讨会上提到的6个主题，由6名提名旅行奖学金的初级调查员涵盖。将尽一切努力鼓励研究生和博士后，以妇女人数均等，并包括少数民族和残疾人。将评估会议目标的可衡量结果，以评估本研讨会对NIH对新研究者的承诺，转化中风研究和NINDS PRG的影响的影响，以实现侧支灌注研究。该提案的重要性是通过为新的研究合作的框架，指导新研究人员的框架而强调的，并通过独特的事件，相关的互动以及随后的共识声明来改善该领域的临床实践。该提案的健康相关性植根于讨论和研究计划，该计划涉及侧支在毁灭性疾病中的有影响力作用的关键优先事项。