Probiotics, Prebiotics, and the Host Microbiome: The Science of Translation

益生菌、益生元和宿主微生物组：转化科学

• 批准号: 8529804
• 负责人: Patricia L Hibberd
• 金额: $ 2.9万
• 依托单位: NEW YORK ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-01 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8529804
• 关键词: Academia; Academy; Address; Affect; Area; Award; Bacteria; Behavior; Bifidobacterium; Biological Response Modifier Therapy; Biology; Child Care; Clinical; Collaborations; Communities; Complementary and alternative medicine; Congresses; Consensus; Data; Decision Making; Development; Diabetes Mellitus; Disabled Persons; Discipline; Disease; Economic Models; Economics; Endocrinology; Epidemic; Expenditure; Fellowship; Female; Fostering; Future; Genome; Goals; Government; Health; Health Benefit; Health Professional; Healthcare; Healthcare Systems; Human; Human Microbiome; Immune; Individual; Industry; Inflammation; Inflammatory Bowel Diseases; Institutes; International; Intervention; Investigation; Knowledge; Lactobacillus; Life; Light; Link; Malnutrition; Medical Research; Metabolic; Metabolic Diseases; Microbiology; Minority; Minority Groups; Mission; Modeling; National Center for Complementary and Alternative Medicine; National Institute of Diabetes and Digestive and Kidney Diseases; Nervous System Physiology; Neurobiology; Neurons; New York; Nutritional; Obesity; Oral; Organism; Participant; Physiology; Policies; Population; Populations at Risk; Prevention; Prize; Probiotics; Process; Public Health; Publications; Publishing; Recommendation; Regulation; Reporting; Research; Research Personnel; Role; Safety; Science; Science Policy; Technical Expertise; Technology; Therapeutic; Therapeutic Intervention; Translating; Translational Research; Translations; Travel; Underrepresented Minority; Woman; abstracting; base; career; clinical care; disability; discount; economic impact; evidence base; functional food; gastrointestinal system; global health; gut microbiota; human disease; immune function; improved; innovation; lectures; meetings; microbiome; multidisciplinary; novel; nutrition; posters; prebiotics; public health relevance; symposium; tool

DESCRIPTION (provided by applicant): The great potential of prebiotics and probiotics for the improvement of public health remains largely unrealized. This one-day conference, "Probiotics, Prebiotics, and the Host Microbiome: The Science of Translation," jointly presented by the International Scientific Association for Probiotics and Prebiotics and The Sackler Institute for Nutrition Science at the New York Academy of Sciences on June 12, 2013, will explore and have important, broad impact on our understanding of the strong convergence of prebiotic and probiotic biology and its role within the human microbiome framework, thereby informing development of future strategies to translate this knowledge into innovative, economical, and population-wide nutritional and biotherapeutic applications of significant public health benefit. Anticipated to convene 200 attendees across a wide range of scientific and clinical disciplines, bacterial species, and regulatory/policy arenas, the meeting will: (i) Provide a neutral forum, through lectures, interactive panels, and networking activities, for discussing current and emerging concepts of prebiotic and probiotic biology, including the effect on the human microbiome - fostering the development of preventative and biotherapeutic strategies to manipulate the microbiome through functional foods; (ii) Showcase early career, female and underrepresented minority investigators via short talks, posters, awards, travel fellowships, and discounted registration; and (iii) Foster collaboration among junior and senior representatives from academia, clinical care, government and regulatory agencies, and the nutrition industry, to promote knowledge exchange leading to successful translation of research into improved interventions, therapies, and policy with regard to functional foods. The conference is especially timely given the increase in robust scientific evidence supporting the beneficial health effects of prebiotics and probiotics, providing great future potential to build on this knowledge. Examining this evidence in order to inform decision making by the public, health care professionals, and policymakers about the integration of prebiotics and probiotics as functional foods and biotherapeutics is particularly urgent in light of the clinical and economic challenges faced by global health care systems, such as the obesity epidemic and malnutrition. Thematically, the conference goals align well with the mission of NCCAM to define, through rigorous scientific investigation, the usefulness and safety of complementary and alternative medicine interventions and their roles in improving health and health care. The inclusion of data relating to obesity, diabetes, and disorders of the gastrointestinal system also aligns well with the mission of the NIDDK. Publication of an enduring, open-access Meeting Report in Annals of the New York Academy of Sciences will inform science policy and ultimately foster the integration of prebiotics and probiotics in health care recommendations for the prevention and treatment of a multitude of human diseases.

描述（由申请人提供）：益生元和益生菌在改善公共卫生方面的巨大潜力在很大程度上尚未实现。这次为期一天的会议“益生菌、益生元和宿主微生物组：转化科学”由国际益生菌和益生元科学协会和萨克勒研究所联合主办 2013 年 6 月 12 日在纽约科学院举行的营养科学研讨会将探索益生元和益生菌生物学的强大融合及其在人类微生物组框架中的作用，并对我们的理解产生重要而广泛的影响，从而为未来的发展提供信息将这些知识转化为具有重大公共健康效益的创新、经济和全民营养和生物治疗应用的战略。预计将召集 200 名来自广泛科学和临床学科、细菌物种以及监管/政策领域的与会者，会议将： (i) 通过讲座、互动小组和网络活动提供一个中立的论坛，讨论当前和益生元和益生菌生物学的新兴概念，包括对人类微生物组的影响——促进预防和生物治疗策略的发展，以通过功能性食品操纵微生物组； (ii) 通过简短的演讲、海报、奖项、旅行奖学金和折扣注册，展示早期职业、女性和代表性不足的少数族裔调查员； (iii) 促进学术界、临床护理、政府和监管机构以及营养行业的初级和高级代表之间的合作，以促进知识交流，从而将研究成功转化为改进的功能性食品干预措施、疗法和政策。鉴于越来越多的有力科学证据支持对健康有益的影响，这次会议显得尤为及时 益生元和益生菌，为进一步发展这些知识提供了巨大的未来潜力。鉴于全球卫生保健系统面临的临床和经济挑战，检查这些证据，以便为公众、卫生保健专业人员和政策制定者提供关于将益生元和益生菌整合为功能性食品和生物治疗药物的决策，这一点尤为紧迫。由于肥胖流行和营养不良。从主题上看，会议目标与 NCCAM 的使命高度契合，即通过严格的科学研究确定补充和替代医学干预措施的有用性和安全性及其在改善健康和保健方面的作用。纳入与肥胖、糖尿病和胃肠系统疾病相关的数据也符合 NIDDK 的使命。在纽约科学院年鉴上发表持久的、开放获取的会议报告将为科学政策提供信息，并最终促进将益生元和益生菌纳入预防和治疗多种人类疾病的医疗保健建议中。