Training in Tissue Engineering and Regenerative Medicine

组织工程和再生医学培训

• 批准号: 8662202
• 负责人: IRVING M SHAPIRO
• 金额: $ 22.85万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8662202
• 关键词: Regenerative Medicine; Tissue Engineering; Training

DESCRIPTION (provided by applicant): The focus of the renewal of the Training Program in Tissue Engineering and Regenerative Medicine is to provide doctoral students with advanced training in biomedical research. The didactic portion of the Program provides an integrated, innovative and rigorous educational experience that has as its goal the repair or regeneration of human tissues and organs and the preservation of the quality of human health. Resources for the program come from a core of well-funded faculty in several departments/divisions at Thomas Jefferson University including Orthopaedic Surgery, Dermatology, Medicine, Surgery, Anatomy and Developmental Biology, Stem Cell Biology, Pathology and Cell Biology and the Rothman Institute. We request support for five predoctoral students in the 01-03 year of the grant and six students in the 04-05 years. There are six program objectives: (1) to integrate contemporary advances in cell, molecular, and developmental biology towards understanding tissue function; (2) to relate fundamental advances in the life sciences to contemporary issues in tissue engineering (3) to foster practical understandings of the pathophysiology of diseases of the skeleton; (4) to develop translational research by working closely with physicians in a clinical and surgical setting; (5) to implement translational research through interactions with scientists in the biotech industry and (6) to build a pipeline of talented individuals for careers in musculoskeletal research The didactic aspects of the training program are embedded in integrating developmental, cell and molecular biology; bioinformatics and functional genomics; tissue engineering and bioimaging; and translational medicine. So as to anchor the program in human disease, clinicians lecture in each of the major courses. By interacting frequently with surgeons who treat the ravages of disease, and by direct observation and discussion with faculty in the clinic and operating room, students develop an appreciation for health problems that are amenable to treatment by tissue engineering and regenerative medicine. Development of translational research is furthered by collaboration with scientists at local biotech companies and laboratories. Against this background, students develop their dissertation research which provides the foundation for their future careers as independent, innovative scientific investigators.

描述（由申请人提供）：组织工程和再生医学培训计划更新的重点是为博士生提供生物医学研究的高级培训。该计划的教学部分提供了一种综合，创新和严格的教育经验，其目标是人类组织和器官的修复或再生，并保留人类健康质量。该计划的资源来自托马斯·杰斐逊大学（Thomas Jefferson University）的多个部门/部门的资金核心，包括骨科外科，皮肤病学，医学，手术，解剖学和发育生物学，干细胞生物学，病理学和细胞生物学以及罗斯曼研究所。我们要求在赠款的01-03年和04-05年的六名学生中为五名专业学生提供支持。有六个程序目标：（1）将当代的进步整合到理解组织功能的细胞，分子和发育生物学方面； （2）将生命科学的基本进步与组织工程中的当代问题联系起来（3），以促进对骨骼疾病病理生理学的实际理解； （4）通过在临床和外科手术环境中与医生紧密合作来开发转化研究； （5）通过与生物技术行业的科学家进行互动和（6）来实施转化研究，以建立有才华的人的肌肉骨骼研究职业的管道。生物信息学和功能基因组学；组织工程和生物成像；和翻译医学。为了确定人类疾病的计划，临床医生在每个主要课程中讲课。通过与治疗疾病破坏的外科医生进行互动，并通过直接观察和与诊所和手术室中的教师进行讨论，学生对健康问题的健康问题产生了欣赏，这些健康问题可受到组织工程和再生医学的治疗。与当地生物技术公司和实验室的科学家合作，可以进一步发展转化研究的发展。在这种背景下，学生们开发了论文研究，为他们作为独立的创新科学研究者的未来职业奠定了基础。