Training in Tissue Engineering and Regenerative Medicine

组织工程和再生医学培训

• 批准号: 7228521
• 负责人: IRVING M SHAPIRO
• 金额: $ 17.4万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7228521
• 关键词: Regenerative Medicine; Tissue Engineering; Training

DESCRIPTION (provided by applicant): The focus of the Training Program in Tissue Engineering and Regenerative Medicine is to provide doctoral students with advanced training in biomedical research with the ultimate goal of designing cell, tissue, and scaffold-based therapies. The didactic portion of the program provides an integrated, innovative and rigorous educational experience that has as its goal the repair or regeneration of human tissues and organs. Resources for the program come from a core of well-funded faculty in several departments or divisions at Thomas Jefferson University. We request support for three predoctoral students in the 01 year of the grant and four students in the 02-04 years; in the 05 year we ask for five slots. There are five program objectives: (1) to integrate contemporary advances in cell, molecular, and developmental biology towards understanding tissue function; (2) to relate fundamental advances in the life sciences to contemporary concepts in tissue engineering (3) to understand the pathogenesis of diseases that afflict the musculoskeletal system; (4) to foster practical understanding of the pathophysiology of diseases of the skeleton and the nature of clinical investigation through industrial and medical cross-training; (5) to build a pipeline of talented individuals for careers in musculoskeletal research. The didactic aspects of the training program are embedded in integrating developmental, cell and molecular biology; bioinformatics and functional genomics; tissue engineering and bioimaging; and translational medicine. So as to anchor the program in human disease, students meet with surgeons in the clinic and operating room to consider health problems that are amenable to treatment by Tissue Engineering and Regenerative Medicine. Development of translational research is furthered by collaboration with scientists at local pharmaceutical companies and laboratories. Against this background, students develop their dissertation research which provides the foundation for their future careers as independent, innovative scientific investigators. The focus of the training program in Tissue Engineering and Regenerative Medicine is to provide doctoral students with advanced training in biomedical research. As a result of their training, these students will generate new knowledge of the diseases that afflict the musculoskeletal system and provide strategies that will serve to ameliorate or prevent diseases that currently afflict a huge number of Americans.

描述（由申请人提供）：组织工程和再生医学培训项目的重点是为博士生提供生物医学研究方面的高级培训，最终目标是设计基于细胞、组织和支架的疗法。该计划的教学部分提供了综合、创新和严格的教育体验，其目标是人体组织和器官的修复或再生。该项目的资源来自托马斯杰斐逊大学多个系或部门的资金雄厚的核心教师。我们请求资助01年的三名博士前学生和02-04年的四名学生； 05年我们要求五个名额。 该项目有五个目标：（1）整合细胞、分子和发育生物学的当代进展，以了解组织功能； (2) 将生命科学的基本进展与组织工程学的当代概念联系起来 (3) 了解影响肌肉骨骼系统的疾病的发病机制； (4) 通过工业和医学交叉培训，培养对骨骼疾病病理生理学和临床研究性质的实际理解； (5) 建立肌肉骨骼研究人才的人才梯队。培训计划的教学内容融入了发育、细胞和分子生物学的整合；生物信息学和功能基因组学；组织工程和生物成像；和转化医学。为了将这个项目扎根于人类疾病，学生们在诊所和手术室与外科医生会面，考虑适合组织工程和再生医学治疗的健康问题。通过与当地制药公司和实验室的科学家合作，进一步促进了转化研究的发展。在此背景下，学生开展论文研究，为他们未来作为独立、创新的科学研究人员的职业生涯奠定基础。 组织工程和再生医学培训项目的重点是为博士生提供生物医学研究的高级培训。通过培训，这些学生将获得有关肌肉骨骼系统疾病的新知识，并提供有助于改善或预防目前困扰大量美国人的疾病的策略。