Training in Tissue Engineering and Regenerative Medicine

组织工程和再生医学培训

• 批准号: 7849727
• 负责人: IRVING M SHAPIRO
• 金额: $ 22.16万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7849727
• 关键词: Regenerative Medicine; Tissue Engineering; Training

DESCRIPTION (provided by applicant): The focus of the Training Program in Tissue Engineering and Regenerative Medicine is to provide doctoral students with advanced training in biomedical research with the ultimate goal of designing cell, tissue, and scaffold-based therapies. The didactic portion of the program provides an integrated, innovative and rigorous educational experience that has as its goal the repair or regeneration of human tissues and organs. Resources for the program come from a core of well-funded faculty in several departments or divisions at Thomas Jefferson University. We request support for three predoctoral students in the 01 year of the grant and four students in the 02-04 years; in the 05 year we ask for five slots. There are five program objectives: (1) to integrate contemporary advances in cell, molecular, and developmental biology towards understanding tissue function; (2) to relate fundamental advances in the life sciences to contemporary concepts in tissue engineering (3) to understand the pathogenesis of diseases that afflict the musculoskeletal system; (4) to foster practical understanding of the pathophysiology of diseases of the skeleton and the nature of clinical investigation through industrial and medical cross-training; (5) to build a pipeline of talented individuals for careers in musculoskeletal research. The didactic aspects of the training program are embedded in integrating developmental, cell and molecular biology; bioinformatics and functional genomics; tissue engineering and bioimaging; and translational medicine. So as to anchor the program in human disease, students meet with surgeons in the clinic and operating room to consider health problems that are amenable to treatment by Tissue Engineering and Regenerative Medicine. Development of translational research is furthered by collaboration with scientists at local pharmaceutical companies and laboratories. Against this background, students develop their dissertation research which provides the foundation for their future careers as independent, innovative scientific investigators. The focus of the training program in Tissue Engineering and Regenerative Medicine is to provide doctoral students with advanced training in biomedical research. As a result of their training, these students will generate new knowledge of the diseases that afflict the musculoskeletal system and provide strategies that will serve to ameliorate or prevent diseases that currently afflict a huge number of Americans.

描述（由申请人提供）：组织工程和再生医学培训计划的重点是为博士生提供生物医学研究的高级培训，其最终目的是设计基于细胞，组织和基于脚手架的疗法。该计划的教学部分提供了一种综合，创新和严格的教育经验，其目标是人类组织和器官的修复或再生。该计划的资源来自托马斯·杰斐逊大学（Thomas Jefferson University）的多个部门或部门的资助良好的教师的核心。我们要求在赠款的01年中为三名专业学生和在02-04年中的四名学生提供支持；在05年中，我们要求五个插槽。 有五个程序目标：（1）将当代进步整合到细胞，分子和发育生物学方面，以理解组织功能； （2）将生命科学的基本进步与组织工程中的当代概念联系起来（3），以了解困扰肌肉骨骼系统的疾病的发病机理； （4）促进对骨骼疾病的病理生理学的实际理解，以及通过工业和医学交叉培训的临床研究性质； （5）为肌肉骨骼研究中的职业生涯建立了一支才华横溢的人。培训计划的教学方面嵌入了整合发育，细胞和分子生物学。生物信息学和功能基因组学；组织工程和生物成像；和翻译医学。为了确定人类疾病的计划，学生会在诊所和手术室与外科医生会面，以考虑通过组织工程和再生医学治疗的健康问题。与当地制药公司和实验室的科学家合作进一步发展了转化研究的发展。在这种背景下，学生们开发了论文研究，为他们作为独立的创新科学研究者的未来职业奠定了基础。 组织工程和再生医学培训计划的重点是为博士生提供生物医学研究的高级培训。由于培训，这些学生将产生对困扰肌肉骨骼系统的疾病的新知识，并提供策略，这些策略将有助于改善或预防目前遭受大量美国人的疾病。