Amplified Attention Training (AAT) for the Treatment of Hemispatial Nelgect

放大注意力训练 (AAT) 用于治疗半侧空间忽视

• 批准号: 9118397
• 负责人: Thomas VanVleet
• 金额: $ 88.79万
• 依托单位: POSIT SCIENCE CORPORATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9118397
• 关键词: Amplified; Attention; Training; AAT; Treatment

DESCRIPTION (provided by applicant): The goal of the current project is to revise a prototype of a computerized attention training program (Amplified Attention Training, AAT) for hemispatial neglect completed in Phase I, and conduct a multi-site, randomized, controlled trial to establish efficacy in this population. As a group, patients with hemispatial neglect tend to have poorer long-term prognosis and are more likely to require managed care than other patient groups with lesions of comparable size. Our recent studies are among the first to demonstrate that AAT, targeting sustained attention & vigilance deficits, can produce lasting benefits. The overall goal of the current project is to measure 3 co-primary outcomes: attention, executive function and functional capacity. Evidence from our Phase I trial shows that AAT can improve attention and executive function deficits common to hemispatial neglect. At the completion of this project we will have outcomes data sufficient for submission to the FDA for clearance as a medical device indicated for cognitive enhancement in hemispatial neglect (ICD-9 Code 781.8).

描述（由申请人提供）：当前项目的目的是修改计算机注意培训计划的原型（放大注意力训练，AAT，AAT），以在第一阶段完成的半专业疏忽，并进行多站点，随机，对照试验以在该人群中建立效率。作为一个小组，与其他大小相当病变的患者组相比，半专利疏忽的患者的长期预后往往较差，并且更有可能需要管理的护理。我们最近的研究是第一个证明AAT以持续关注和警惕性赤字为目标的AAT可以产生持久的好处。当前项目的总体目标是衡量3个共同成果：注意力，执行功能和功能能力。 我们第一阶段试验的证据表明，AAT可以改善Hemispatial忽视常见的注意力和执行功能缺陷。该项目完成后，我们将拥有足够的结果数据，足以提交FDA以进行清除，以作为一种医疗设备，以指示半专利疏忽的认知增强（ICD-9代码781.8）。

项目成果

Randomized control trial of computer-based rehabilitation of spatial neglect syndrome: the RESPONSE trial protocol.

• DOI: 10.1186/1471-2377-14-25
• 发表时间: 2014-02-07
• 期刊: BMC neurology
• 影响因子: 2.6
• 作者: Vleet TV;DeGutis J;Dabit S;Chiu C
• 通讯作者: Chiu C