Pathlogy Shared Resource

病理学共享资源

基本信息

批准号：
8369398
负责人：
MICHELE CARBONE
金额：
$ 4.83万
依托单位：
UNIVERSITY OF HAWAII AT MANOA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-07-01 至 2017-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8369398
关键词：
Advisory Committees Area Atlases Basic Science Biocompatible Materials Biological Assay Biological Markers Blood specimen Breast Caliber Cancer Center Cancer Center Support Grant Cancer Etiology Certification Clinical Clinical Research Collection Colorectal Colorectal Cancer Committee Members Confidentiality of Patient Information Consent Consultations Country County Custom Data Data Element Databases Decision Making Development Documentation Endometrium Epidemiologic Studies Excision Female Genital Neoplasms Freezing Fresh Tissue Funding Future Government Hawaii Health Insurance Portability and Accountability Act Hematoxylin and Eosin Staining Method Histology Histopathology Hospitals Human Human Subject Research Image Immunohistochemistry In Situ Hybridization Individual Institution Institutional Review Boards International Iowa Laboratories Laws Link Liver Los Angeles Malignant Neoplasms Malignant neoplasm of liver Malignant neoplasm of ovary Medical Medical center Methods Microscopic Microscopy Names Operative Surgical Procedures Ovary Pancreas Paraffin Paraffin Embedding Parents Pathologic Pathologist Pathology Patients Performance Periodic acid Schiff stain method Population Precancerous Conditions Preparation Process Protocols documentation Provider Qualifying Race Reagent Recording of previous events Reporting Research Research Activity Research Personnel Research Project Grants Research Proposals Resource Sharing Resources Retrieval SEER Program Sampling Savings Services Silver Site Slide Specific qualifier value Specimen Stage at Diagnosis Staining method Stains System Testing Time Tissue Banking Tissue Banks Tissue Microarray Tissue Procurements Tissues Translational Research Transplantation Trichrome stain method Tumor Tissue Universities Work age group authority base biobank cancer care cancer genome case-by-case basis computerized cost experience falls human subject laser capture microdissection malignant breast neoplasm material transfer agreement meetings member population based prevent prognostic programs prospective protocol development repository research study sample collection sample fixation technology development tissue resource tool tumor

项目摘要

The Pathology Shared Resource (PSR) was created approximately 7 years ago to provide histology and tissue procurement services to support basic, epidemiologic, translational, and clinical research studies conducted both within and outside of the University of Hawai'i Cancer Center (UHCC). Prior to the existence of the PSR, tissue based research at the UHCC was severely limited due to lack of a centralized histopathology service and tissue repository. Since its establishment, usage of the PSR has consistently increased and has facilitated multiple high quality research endeavors by UHCC members. Current services offered by the Resource include a full range of histology services, professional pathology consultation, as well as specialized laboratory services such as tissue microarray (TMA) construction and consultation for laser-capture microdissection (LCM). In addition to these functions, the PSR manages a large, clinically annotated archival tissue repository and facilitates investigator-initiated fresh tissue collection from area hospitals. Future directions for the PSR include establishment of a prospectively collected biorepository in partnership with Queens Medical Center (QMC), the largest cancer care provider in Hawai'i, as well as other consortium hospital members. As a newly emerging facility, the PSR was not supported by the CCSG during the prior funding period. Given that the PSR is now a mature enterprise whose endeavors are expected to continue to expand, we now request CCSG support. CCSG support will also be crucial to the future functioning of this resource, in view of the recent termination of SEER funding for the archival tissue repository in 2010.

病理学共享资源 (PSR) 大约于 7 年前创建，旨在提供组织学和组织采购服务，以支持在夏威夷大学癌症中心 (UHCC) 内外进行的基础、流行病学、转化和临床研究。在 PSR 存在之前，由于缺乏集中的组织病理学服务和组织储存库，UHCC 的组织研究受到严重限制。自成立以来，PSR 的使用量不断增加，并促进了 UHCC 成员的多项高质量研究工作。该资源目前提供的服务包括全方位的组织学服务、专业病理学咨询以及专业实验室服务，例如组织微阵列（TMA）构建和激光捕获显微切割（LCM）咨询。除了这些功能之外，PSR 还管理一个大型的、有临床注释的档案组织存储库，并促进研究者从地区医院收集新鲜组织。 PSR 的未来方向包括与夏威夷最大的癌症护理提供者皇后医疗中心 (QMC) 以及其他联盟医院成员合作建立一个前瞻性收集的生物样本库。作为一个新兴的设施，PSR 在之前的资助期间没有得到 CCSG 的支持。鉴于 PSR 现在是一家成熟的企业，其业务预计将继续扩大，我们现在请求 CCSG 支持。鉴于最近于 2010 年终止了对档案组织存储库的 SEER 资助，CCSG 的支持对于该资源的未来运作也至关重要。