Comorbidity: Substance Use Disorders and Other Psychiatric Conditions

合并症：药物使用障碍和其他精神疾病

• 批准号: 8847313
• 负责人: JAMES R. ALLEN
• 金额: $ 26.52万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8847313
• 关键词: Comorbidity; Substance Use Disorder

DESCRIPTION (provided by applicant): Long-term goals: Among the current portfolio of NIDA funded training grants, none have comorbidity as a primary focus. This is striking given co-occurrence prevalence of Substance Use Disorders (SUD) with other psychiatric conditions and health conditions (e.g. diabetes), and the extent to which either SUD or the comorbid disorder can go under- or untreated in conventional treatment settings. Enhancing research expertise to improve diagnostic, treatment and prevention strategies is essential. The proposed program will develop a cadre of scientists with research expertise in comorbidity mechanisms, antecedents and correlates, diagnostics, and psychosocial and pharmacological interventions. Component objectives are to provide each trainee with a working knowledge of comorbidity research including: (a) translational science from Early Phase Clinical Trials to Community Based Participatory Research perspectives; (b) effective research strategies for comorbid conditions across populations and ethnic and cultural groups (e.g. American Indian, Hmong, Somali). Accomplishing programmatic features will capitalize on (a) the spectrum of faculty expertise providing mentoring across multiple areas, and (b) integration across training programs and departments. Key Elements: (1) Involvement of scientists and clinicians with diverse expertise and a core internal advisory group. Primary sites (4 postdoctoral trainees, 2 yrs each) are the Departments of Psychiatry (UMN Twin Cities) and Biobehavioral Health & Population Science (UMN Duluth), supported by the Psychology Department (UMTC) and other UMN entities; (2) Recruitment, including under represented group outreach, of rigorously screened PhD and MD candidates with SUD and comorbidity as primary career focus; (3) Training with an interdisciplinary mentoring team (primary & 2 secondary mentors) with complementary expertise; (4) Formal training plans with clear milestones including trainee development of an NIH application initiated in Year 1; (5) Active research, seminars, didactic course work, workshops, and development of management, ethics, and regulatory expertise; (6) Dynamic program administration entailing monitoring with enhancements and problem resolution along with continued contact with trainees after completion and; (7) Annually convened external advisory group. Resources: Mentor funding sources include NIH Institutes, NSF, Minnesota Medical Foundation, and pharmaceutical industry. Key Personnel and Primary Mentors are directors of clinics, centers, or departments with significant resources. The program focuses on trainee expertise in SUD co-occurring with psychiatric disorders (Anxiety, ADHD, Borderline, Eating, Depression, Schizophrenia, Trauma).

描述（由申请人提供）：长期目标：在NIDA资助的培训补助金的当前投资组合中，没有一个合并症是主要重点。鉴于物质使用障碍（SUD）与其他精神病疾病和健康状况（例如糖尿病）的同时流行率，以及在常规治疗环境中的SUD或合并症可能不足或未经治疗的程度。提高研究专业知识以改善诊断，治疗和预防策略至关重要。拟议的计划将在合并症机制，先决条件和相关性，诊断和心理社会和药理干预方面发展具有研究专业知识的科学家干部。组件目标是为每个学员提供合并症研究的工作知识，包括：（a）从早期临床试验到基于社区的参与性研究角度的转化科学； （b）跨种族，种族和文化群体合并条件的有效研究策略（例如美洲印第安人，苗族，索马里）。完成程序化功能将利用（a）在多个领域提供指导的教师专业知识的范围，以及（b）跨培训计划和部门的集成。关键要素：（1）具有不同专业知识和核心内部咨询小组的科学家和临床医生的参与。由心理学部（UMTC）和其他UMN实体支持的主要地点（4年的学员，每个2年）是精神病学部（UMN Twin Cities）和Biobehavioral Health and人口科学（UMN Duluth）和其他UMN实体的支持； （2）招聘，包括在代表的团体外展，以严格的筛查博士学位和MD候选人为主要职业焦点； （3）具有互补专业知识的跨学科指导团队（小学和2个次要导师）的培训； （4）具有清晰里程碑的正式培训计划，包括在第一年发起的NIH申请的学员开发； （5）积极的研究，研讨会，教学课程工作，讲习班以及管理，道德和监管专业知识的发展； （6）动态计划管理需要增强和解决问题的监控，以及完成后与受训者的持续联系； （7）每年召集的外部咨询小组。资源：导师资助来源包括NIH机构，NSF，明尼苏达州医疗基金会和制药行业。主要人员和主要导师是具有大量资源的诊所，中心或部门的董事。该计划的重点是与精神疾病（焦虑，多动症，边缘，饮食，抑郁，精神分裂症，创伤）共同出现的SUD的学员专业知识。