Training in Botanical Approaches to Combat Metabolic Syndrome

对抗代谢综合症的植物方法培训

• 批准号: 8807309
• 负责人: PHILLIP J BRANTLEY
• 金额: $ 44.7万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-05-01 至 2020-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8807309
• 关键词: Botanicals; Metabolic syndrome; Training; combat

DESCRIPTION (provided by applicant): Today's researchers need to understand the applications of molecular and genetic approaches as well as the methods for investigating the function of target genes and the effect specific botanicals may have on these processes. Postdoctoral training will be directed toward evaluating the interactions between botanical characterization and molecular/genetic/physiologic approaches at both the basic science and clinical research areas to achieve the ultimate goal of understanding how botanicals can contribute to health maintenance. Thus, a resubmission of a renewal application titled, "Training in Botanical Approaches to Combat Metabolic Syndrome" is proposed. The continued objective of this training program is to train both Ph.D. and M.D. postdoctoral fellows to become productive research scientists capable of establishing scientific careers that further the efforts o understand the role of botanicals on the complex interactions between genetic, molecular and physiological aspects of the metabolic syndrome and for maintaining human health. Specifically, we will continually aim to bridge the divide between the plant discovery and characterization approach and the molecular biology/physiological approach. We are requesting 16 full-time postdoctoral trainee stipends across the five-year grant period. Trainees will be supported for two to three years. Each postdoctoral fellow will be encouraged to develop interdisciplinary research efforts to understand the effect and action of botanicals on components of the metabolic syndrome. The program will take advantage of the synergy and the cutting-edge technologies of an NCCAM sponsored Botanical Research Center composed of the wide range of research approaches to metabolic syndrome that are available at the Pennington Biomedical and the plant science expertise of the Rutgers Department of Plant Biology and Pathology. This broad-based training program will enable trainees to establish successful research careers in academia, academic medicine, government agencies and in the private sector in the study of botanicals and metabolic disease.

描述（由申请人提供）：当今的研究人员需要了解分子和遗传学方法的应用以及研究靶基因功能的方法以及特定植物药可能对这些过程产生的影响。博士后培训将旨在评估基础科学和临床研究领域植物学特征与分子/遗传/生理学方法之间的相互作用，以实现了解植物学如何促进健康维护的最终目标。因此，建议重新提交题为“对抗代谢综合征的植物方法培训”的续展申请。该培训计划的持续目标是培养博士生和博士生。博士后研究员成为富有成效的研究科学家，能够建立科学事业，进一步了解植物药在代谢综合征的遗传、分子和生理方面之间复杂相互作用中的作用，并维持人类健康。具体来说，我们将继续致力于弥合植物发现和表征方法与分子生物学/生理学方法之间的鸿沟。我们请求在五年资助期内为 16 名全职博士后实习生提供津贴。学员将获得两到三年的支持。我们将鼓励每位博士后开展跨学科研究工作，以了解植物药对代谢综合征组成部分的影响和作用。该计划将利用 NCCAM 资助的植物研究中心的协同作用和尖端技术，该中心由彭宁顿生物医学中心提供的各种代谢综合征研究方法和罗格斯大学植物系的植物科学专业知识组成。生物学和病理学。这一基础广泛的培训计划将使学员能够在学术界、学术医学、政府机构和私营部门的植物药和代谢疾病研究领域建立成功的研究生涯。