Training in Botanical Approaches to Combat Metabolic Syndrome

对抗代谢综合症的植物方法培训

• 批准号: 8474595
• 负责人: PHILLIP J BRANTLEY
• 金额: $ 40.47万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8474595
• 关键词: Botanicals; Metabolic syndrome; Training; combat

DESCRIPTION (provided by applicant): The scientists of the Pennington Biomedical Research Center, LSU Ag Center, and the Biotech Center at Rutgers, as part of their collaboration in the BRC, are committed to training in research. A specific aim of the BRC is to expand the critical mass of investigators addressing botanical research by identifying, recruiting, and mentoring promising young investigators. Thus, a resubmission research training program application titled, "Training in Botanical Approaches to Combat Metabolic Syndrome" is proposed for the BRC. The objective of this proposed training grant is to train both Ph.D. and M.D. postdoctoral fellows who possess graduate training in research methods and laboratory techniques to become productive research scientists capable of establishing scientific careers that further the efforts to understand the role of botanicals on the complex interactions between genetic, molecular and physiological aspects of the metabolic syndrome. Today's researchers need to understand the applications of the molecular and genetic approaches as well as the methods for investigating the function of target genes and the effect specific botanicals may have on these processes. It is difficult to get such a wide oversight or expertise during predoctoral programs. Hence, it is important to provide opportunities at the postdoctoral level for training in complementary areas. Our postdoctoral training will be directed towards this goal, enhancing research interactions between botanical characterization and molecular/genetic/physiologic approaches at both the basic science and clinical research areas. Specifically, we aim to bridge the divide between the plant discovery/characterization approach and the molecular biology/physiological approach. We are requesting 14 full-time Ph.D. or M.D. postdoctoral trainee stipends for the five-year grant period. Trainees will be supported for two to three years. We are requesting five full-time postdoctoral trainee stipends for the initial year of the grant; two entry level and three third year postdocs. Each postdoctoral fellow will be encouraged to develop interdisciplinary research efforts to understand the effect and action of botanicals on components of the metabolic syndrome. The program will take advantage of the cutting-edge technologies and the wide range of research efforts related to botanicals and metabolic syndrome that are available at the Pennington Center and the Biotech Center at Rutgers. This broad-based training program will enable trainees to establish successful research careers in academia, academic medicine, government agencies and in the private sector in the study of botanicals and metabolic disease.

描述（由申请人提供）：彭宁顿生物医学研究中心、路易斯安那州立大学农业中心和罗格斯大学生物技术中心的科学家作为 BRC 合作的一部分，致力于研究培训。 BRC 的一个具体目标是通过识别、招募和指导有前途的年轻研究人员来扩大植物学研究研究人员的临界数量。因此，为 BRC 提出了一项名为“对抗代谢综合征的植物方法培训”的重新提交研究培训计划申请。 拟议的培训补助金的目的是培训博士生和博士生。医学博士博士后研究员，他们接受过研究方法和实验室技术方面的研究生培训，成为富有成效的研究科学家，能够建立科学事业，进一步努力了解植物药在代谢综合征的遗传、分子和生理方面之间复杂相互作用中的作用。当今的研究人员需要了解分子和遗传学方法的应用以及研究靶基因功能的方法以及特定植物药可能对这些过程产生的影响。在博士前项目期间很难获得如此广泛的监督或专业知识。因此，提供博士后级别的互补领域培训机会非常重要。我们的博士后培训将针对这一目标，加强基础科学和临床研究领域植物学表征与分子/遗传/生理学方法之间的研究互动。具体来说，我们的目标是弥合植物发现/表征方法和分子生物学/生理学方法之间的鸿沟。我们需要 14 名全职博士。或五年资助期内的医学博士后实习生津贴。学员将获得两到三年的支持。我们要求在资助的第一年提供五名全职博士后实习生津贴；两名入门级博士后和三名三年级博士后。我们将鼓励每位博士后开展跨学科研究工作，以了解植物药对代谢综合征组成部分的影响和作用。该计划将利用彭宁顿中心和罗格斯大学生物技术中心提供的尖端技术以及与植物和代谢综合征相关的广泛研究成果。这一基础广泛的培训计划将使学员能够在学术界、学术医学、政府机构和私营部门的植物药和代谢疾病研究领域建立成功的研究生涯。