CARIBBEAN PRIMATE RESEARCH CENTER

加勒比灵长类动物研究中心

• 批准号: 8432761
• 负责人: Melween I. Martinez
• 金额: $ 211.24万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-04-15 至 2015-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8432761
• 关键词: Accounting; Acquired Immunodeficiency Syndrome; Anatomy; Animal Husbandry; Animals; Behavior; Behavioral; Behavioral Genetics; Behavioral Research; Biomedical Research; Cancer Center Support Grant; Caribbean region; Circadian Rhythms; Collection; Communicable Diseases; Communities; Demography; Development; Diabetes Mellitus; Disease; Ecology; Education; Film; Funding; Future; General Population; Genetic; Gerontology; Grant; Health; Hematology; Housing; Human; Human Resources; Income; Individual; International; Investigation; Island; Laboratories; Macaca mulatta; Macular degeneration; Medical; Modeling; Monkeys; Morphology; National Center for Research Resources; Neurodegenerative Disorders; Neurosciences; Ophthalmology; Parasitology; Physical Anthropology; Pilot Projects; Play; Population; Primates; Provider; Puerto Rico; Recruitment Activity; Reporting; Reproductive Biology; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Role; SIV; Science; Scientist; Simian Retroviruses; Skeleton; Social Behavior; Specific Pathogen Frees; Television; Training Programs; United States; United States National Institutes of Health; Veterinarians; Virus; age related; animal care; animal resource; developmental genetics; effective therapy; germ free condition; human disease; model development; nonhuman primate; programs; public health relevance; skeletal; therapy development; vaccine development; vaccinology; virology

DESCRIPTION (provided by applicant): This grant will provide continued NIH support to maintain the Caribbean Primate Research Center (CPRC). The CPRC consists of four integrated facilities: (1) Cayo Santiago, a unique free-ranging island colony of Indian-origin rhesus monkeys (Macaca mulatta); (2) the Sabana Seca Field Station, the CPRC's headquarters located 10 miles outside of San Juan, that houses rhesus monkeys derived from the Cayo Santiago colony in various outdoor configurations for biomedical and behavioral studies that are not feasible on free-ranging animals; (3) the Laboratory of Virology and Genetics (LVG), located on the Medical Sciences Campus (MSC), in San Juan; and (4) the Laboratory of Primate Morphology and Genetics (LPMG), which is also located on the MSC, and houses the CPRC Skeletal Collections, unique assemblages of nonhuman primate skeletons for genetic, developmental, pathological and anatomical research. As described in this proposal, CPRC is organized into four complementary and integrated divisions: Primate Resources, Virology and Genetics, Behavior and Neurosciences, and Primate Morphology & Genetics. Funds are requested in this application only to maintain CPRC basic infrastructure of Primate Resources, which are used to support numerous research projects across the United States. This core grant will also allow CPRC to seek additional support to launch collaborative research projects with mainland and international investigators. With continued NIH support, the CPRC will remain a significant national research resource and will be able to provide healthy Indian-origin rhesus monkeys of defined genetic and virological background to NIH-sponsored research programs.

描述（由申请人提供）：这笔赠款将提供 NIH 的持续支持，以维持加勒比灵长类动物研究中心 (CPRC)。 CPRC 由四个综合设施组成：(1) 圣地亚哥岛，一个独特的自由放养的印度恒河猴 (Macaca mulatta) 岛屿群落； (2) 位于圣胡安郊外 10 英里的 CPRC 总部 Sabana Seca 野外站，在各种户外配置中饲养来自圣地亚哥岛殖民地的恒河猴，用于生物医学和行为研究，而这些在自由放养的动物身上是不可行的； (3) 病毒学和遗传学实验室 (LVG)，位于圣胡安医学科学园区 (MSC)； (4) 灵长类动物形态学和遗传学实验室 (LPMG)，也位于 MSC，并拥有 CPRC 骨骼收藏，这是用于遗传、发育、病理和解剖学研究的非人类灵长类骨骼的独特组合。如本提案所述，CPRC 分为四个互补且综合的部门：灵长类动物资源、病毒学和遗传学、行为和神经科学以及灵长类动物形态学和遗传学。本申请中请求的资金仅用于维护 CPRC 灵长类资源的基础设施，这些基础设施用于支持美国各地的众多研究项目。这笔核心拨款还将允许 CPRC 寻求额外支持，以与大陆和国际研究人员开展合作研究项目。在 NIH 的持续支持下，CPRC 将仍然是重要的国家研究资源，并将能够为 NIH 资助的研究项目提供具有明确遗传和病毒学背景的健康的印度恒河猴。