Yoga as a Complementary Therapy for Type 2 Diabetes: An Initial Investigation

瑜伽作为 2 型糖尿病的补充疗法：初步调查

基本信息

批准号：
8947179
负责人：
Beth C Bock
金额：
$ 23.25万
依托单位：
MIRIAM HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-01 至 2017-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8947179
关键词：
Accounting Adult Aerobic Exercise Affect American Anxiety Attention Behavior Behavior Therapy Behavioral Belief Biological Markers Blood Glucose Body Composition Body mass index Breathing Chronic Disease Clinical Trials Complementary therapies Complications of Diabetes Mellitus Country Data Diabetes Mellitus Diagnosis Diet Elderly Exercise Eye Fasting Feasibility Studies Focus Groups Future Glucose Glycosylated hemoglobin A Goals Health Health behavior Healthcare Systems Home environment Hydrocortisone Intervention Investigation Jogging Kidney Lead Measures Mediator of activation protein Meditation Methodology Modeling Nerve Non-Insulin-Dependent Diabetes Mellitus Outcome Participant Patients Perception Pharmaceutical Preparations Physical Fitness Physical activity Plasma Population Protocols documentation Psychological Stress Randomized Randomized Controlled Trials Relaxation Role Salivary Self Care Self Efficacy Stress Stroke Testing Time Training Walking Yoga base cardiovascular disorder risk design diabetes management diabetic diet and exercise exercise adherence glycemic control heart disease risk improved mindfulness prevent programs psychologic randomized trial satisfaction secondary outcome sedentary stress management stress resilience waist circumference

项目摘要

DESCRIPTION (provided by applicant): Diabetes affects nearly 29 million Americans and another 86 million adults in the U.S. are prediabetic. Type 2 diabetes (T2DM) accounts for 90-95% of all diabetes cases in adults. Uncontrolled diabetes, over time, can cause serious damage to kidneys, eyes, and nerves and increases the risk of heart disease and stroke. Controlling blood glucose level is crucial to avoid these serious complications. Traditional aerobic exercise (e.g., walking, jogging, cycling) is known to improve blood glucose levels in patients with T2DM. Yoga, an ancient eastern practice, shares many of the same benefits as exercise. Like aerobic exercise, yoga practice can elicit improvements in health related aspects of physical fitness. Yoga is also a mindfulness practice with emphasis on relaxation, meditation, and deep breathing, and therefore may have special relevance to people with T2DM. Yoga by increasing mindfulness and parasympathetic activity can alleviate stress. Randomized trials with healthy and diseased participants have shown the benefit of yoga on stress reduction. By inducing stress resilience, yoga may prevent stress-induced rise in cortisol, thus controlling rise in blood glucose levels. Moreover, by reducing stress, and increasing mindfulness, yoga may also lead to improved self-care behaviors including improved diet and physical activity. The role of yoga as a complementary therapy for diabetics within the socio-cultural context of the U.S. needs additional examination. The purpose of the current proposal is to test a yoga intervention for adults with T2DM and to gather data on the feasibility and acceptability of yoga compared to a contact control for glycemic control. We will conduct a pilot randomized controlled study with participants randomly assigned to 1) Yoga intervention, or 2) Group Walking program (control). Focus groups will be conducted with participants at the end of the intervention to identify facilitators and barriers to yoga practice and to examine their perceptions and beliefs about yoga and its relationship to stress and diabetes management. We will explore the effect of yoga on stress (biomarker = salivary cortisol) that may act as a mechanism of action underlying the efficacy of yoga for improved glycemic control. We will also measure HbA1c levels, fasting and postprandial plasma glucose at baseline, end of treatment (12-weeks), 6- and 9- month follow-ups. Study feasibility and acceptability will be assessed using participant recruitment, attendance and retention rates, and compliance with study protocols and general satisfaction with the program. Results from this study will provide scientific basis for a future larger clinical trial. Yoga, if found to offer advantages for glycemic control, can have potential for high impact on current practices of diabetes management.

描述（由申请人提供）：糖尿病会影响近2900万美国人，而在美国等人（T2DM）的另外8600万成年人占所有糖尿病的90-95％，随着时间的流逝，所有糖尿病都会造成严重伤害。神经并增加了心脏病和中风的风险。与身体的健康相关，也可以提高瑜伽，并且深呼吸，因此可能与T2DM的人有特殊的相关性。在减少压力的血液中，瑜伽可能会改善自我保健行为，包括改善饮食和身体活性。通过T2DM并收集有关瑜伽的可行性和可接受性的数据，我们将与随机分配给1）组的参与者随机控制。瑜伽练习并检查他们对压力和糖尿病管理的关系。，基线时的快速葡萄糖（治疗终结）将使用参与者招聘，出勤率和保留率进行评估，并使用研究方案和对该计划的满意度进行评估。临床试验。