Biostatistics and Informatics Shared Resource

生物统计学和信息学共享资源

• 批准号: 8369399
• 负责人: MICHELE CARBONE
• 金额: $ 11.35万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8369399
• 关键词: Algorithms; Area; Behavior; Bioinformatics; Biological; Biometry; Cancer Center; Cancer Center Support Grant; Case Report Form; Clinical Trials; Clinical trial protocol document; Code; Collaborations; Complex; Computer software; Computing Methodologies; Consultations; Data; Data Analyses; Data Collection; Data Set; Data Storage and Retrieval; Databases; Detection; Development; Diet; Ensure; Environment; Funding; Genetic; Goals; Grant; Hawaii; Housing; Human; Image; Informatics; Information Systems; Intervention; Language; Logistic Models; Manuscripts; Measurement; Measures; Meta-Analysis; Methods; Modeling; Molecular; Monitor; NCI Center for Cancer Research; Noise; Observational Study; Output; Paper; Participant; Persons; Physical activity; Play; Policies; Population; Population Study; Preparation; Process; Program Reviews; Proportional Hazards Models; Protocols documentation; Publications; Randomized; Research; Research Activity; Research Design; Research Personnel; Research Project Grants; Resources; Risk; Role; Safety; Sample Size; Sampling; Schedule; Security; Services; Signal Transduction; Solutions; Statistical Data Interpretation; Statistical Models; Stratification; Structure; Support System; System; Systems Biology; Techniques; United States National Institutes of Health; Universities; Visual; Workload; Writing; base; cancer Biomedical Informatics Grid; computer infrastructure; computer program; data management; design; graphical user interface; improved; informatics shared resource; information processing; instrument; interest; meetings; member; programs; scientific computing; sound; sun protection; validation studies

The Biostatistics and Informatics Shared Resource (BISR) plays an essential role in the research activities of the University of Hawai'i Cancer Center. The biostatistics function, established in 1995, and the informatics function, established in 2004, have recently been consolidated in order to provide a seamless support system to Cancer Center members. The formation of a cohesive group of statisticians and informaticians helps assure uniform excellence in all aspects of data management and analysis across all projects and allows for an exchange of methodological approaches leading to more efficient and creative solutions. The overarching goal of the BISR is to ensure that sound analytic principles are followed, thereby improving the quality of the research enterprise of the Cancer Center. Eighteen members and 14.82 FTE are currently included in the Biostatistics and Informatics Shared Resource. Services provided include consultation on study design, data collection, data management, data analysis, statistical programming, bioinformatics and systems biology, interpretation of findings, and clinical trials protocol support. During the last cycle of the CCSG grant, members of the resource contributed to 199 publications, including 155 as co-authors, served as co-investigators on 75 single project grants and 2 multi-project grants, and contributed to the submission of 90 grants, 45 of which were funded. The resource will continue to meet the biostatistical and informatics needs of the University of Hawai'i Cancer Center, will continue to perform methodological research important to the research of cancer center members, and will continue to develop a computational infrastructure for the storage and processing of high-dimensional data.

生物统计和信息学共享资源 (BISR) 在夏威夷大学癌症中心的研究活动中发挥着重要作用。 1995 年建立的生物统计职能和 2004 年建立的信息学职能最近得到了整合，以便为癌症中心成员提供无缝支持系统。统计学家和信息学家组成的有凝聚力的团队有助于确保所有项目的数据管理和分析的各个方面的统一卓越，并允许交换方法论，从而产生更高效和更具创造性的解决方案。 BISR 的首要目标是确保遵循合理的分析原则，从而提高癌症中心研究事业的质量。目前，生物统计和信息学共享资源中包含 18 名成员和 14.82 名 FTE。提供的服务包括研究设计、数据收集、数据管理、数据分析、统计编程、生物信息学和系统生物学、结果解释和临床试验方案支持方面的咨询。在 CCSG 资助的最后一个周期中，该资源的成员为 199 份出版物做出了贡献，其中 155 人作为共同作者，担任 75 项单一项目资助和 2 项多项目资助的共同研究员，并为提交 90 项资助做出了贡献，其中 45 项获得资助。该资源将继续满足夏威夷大学癌症中心的生物统计和信息学需求，将继续进行对癌症中心成员的研究重要的方法学研究，并将继续开发用于存储和处理的计算基础设施高维数据。