Clinical Sciences Core Research Plan (C)

临床科学核心研究计划（C）

基本信息

批准号：
8675789
负责人：
Margaret A Fischl
金额：
$ 20.7万
依托单位：
UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-06-01 至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/8675789
关键词：
AIDS/HIV problem Acquired Immunodeficiency Syndrome Advisory Committees Applications Grants Area Award Behavioral Behavioral Research Biological Biometry Blood Cancer Center Support Grant Centers for Disease Control and Prevention (U.S.)Clinical Clinical Data Clinical Research Clinical Sciences Clinical Services Clinical Trials Cohort Studies Collaborations Community Outreach Complement Consent Forms Consult Data Data Analyses Data Set Detection Development Devices Disease Drug Industry Education Enrollment Epidemiology Evolution Fostering Funding Generations Goals Good Clinical Practice Grant Growth HIV HIV Infections Head Human Human Resources Industry Institutes Institutional Review Boards Interdisciplinary Study Investigational Drugs Laboratories Leadership Left Life Cycle Stages Manuscripts Medical Methodology Mission Monitor Pathogenesis Phase Pilot Projects Play Population Predictive Factor Preparation Prevention Prevention Research Productivity Recombinants Research Research Design Research Infrastructure Research Personnel Research Priority Resource Sharing Rights Role Safety Sample Size Science Scientist Services Social Welfare Specimen Staging Statistical Methods Therapeutic Human Experimentation Tissues Training Translational Research United States Health Resources and Services Administration United States National Institutes of Health Universities Vaccine Research Viral abstracting assay development base behavioral/social science experience human data human subject human tissue innovation institutional biosafety committee meetings member multidisciplinary preclinical study protocol development repository research facility response sample collection social success

项目摘要

The Clinical Sciences Core will be led by Dr. Margaret FischI as Director, Dr. Charles Mitchell as Co- Director, and Dr. Kristopher Arheart as Biostatistical Subcore leader. The Clinical Sciences Core (CSC) during the past four years provided essential services that both enhanced the productivity and capacity of Miami CFAR investigators and new/young investigators and fostered collaborative research among clinical, behavioral/social, and basic scientists that involved human subjects, human data, and biological specimen collection and distribution. The CSC provided support and services to over 80 investigators for over 120 projects support by 7 NIH institutes, 6 NIH funded networks, the CDC, the HRSA, and the pharmaceutical industry and to over 100 CFAR members including young/new investigators. The mission of the CSC is to provide scientific leadership and infrastructure support that advances multidisciplinary collaborative research in basic, clinical, epidemiologic, behavioral/social, and translational sciences in the prevention, detection, treatment, and cure of HIV/AIDS. The mission and goals of the CSC are needs base driven by the research priorities of the UM CFAR investigators and their projects and by the CSC priority to foster synergy and produce an economy of scale. The CSC will focus on enhancing the capacity for HIV/AIDS research in NIH Networks, promoting and supporting innovative NIH HIV/AIDS research initiatives, and facilitating and promoting scientific interactions between CFAR investigators and industry. The CSC will accomplish this through the provision of Biostatistical study design expertise and biostatical services, provision of clinical data and biological specimen repository to foster collaborative immunopathogenesis research, assistance with IRB and regulatory agency submissions, and provision of state-of-the-art clinical research facilities with clinical services. The CSC is essential to the continued growth and success of the Miami CFAR, as it has provided critical expertise and services for advancing multidisciplinary clinical translation research in therapeutic, vaccine and prevention research that is not duplicated by other Cores or facilities at the University of Miami.

临床科学核心将由玛格丽特·菲舍（Margaret Fischi）博士担任董事，查尔斯·米切尔（Charles Mitchell）博士担任联合主任，而克里斯托弗·阿尔哈特（Kristopher Arheart）博士则为生物统计学子核心领导人。在过去的四年中，临床科学核心（CSC）提供了重要的服务，从而提高了迈阿密CFAR研究者和新/年轻研究人员的生产力和能力，并在临床，行为/社会和基本科学家中培养了涉及人类受试者，人类数据和生物标本收集和分配的基础科学家之间的合作研究。 CSC为80多名调查人员提供了支持和服务，为70多个NIH Institutes，6个NIH资助的网络，CDC，HRSA和制药行业以及包括年轻/新调查人员在内的100多名CFAR成员提供了支持和服务。 CSC的使命是提供科学领导力和基础设施支持，从而在预防，临床，流行病学，行为/社会和转化科学方面推进了艾滋病毒/艾滋病的基础，临床，流行病学，行为/社会和转化科学的多学科合作研究。 CSC的使命和目标是由UM CFAR调查人员及其项目以及CSC优先事项的研究重点驱动的基础，以促进协同作用和发展规模经济。 CSC将着重于增强NIH网络中艾滋病毒/艾滋病研究的能力，促进和支持创新的NIH HIV/艾滋病研究计划，并促进和促进和促进CFAR研究人员与行业之间的科学互动。 CSC将通过提供生物统计研究设计专业知识和生物统计服务，提供临床数据和生物学标本存储库来实现这一目标，以促进协作性免疫病变研究，IRB和监管机构提交的协助以及提供最新的临床研究机构与临床服务的最新临床研究。 CSC对于迈阿密CFAR的持续增长和成功至关重要，因为它为推进迈阿密大学其他核心或设施的治疗，疫苗和预防研究方面的多学科临床翻译研究提供了重要的专业知识和服务。