Gulf Longitudinal Follow-up (GuLF) Study

海湾纵向随访（GuLF）研究

• 批准号: 8929812
• 负责人: Dale P Sandler
• 金额: $ 98.06万
• 依托单位: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8929812
• 关键词: Area; Biological; Biological Markers; Burn injury; Cardiovascular system; Chemicals; Clinical; DNA Damage; Data; Data Collection; Development; Disasters; Economics; Environment; Environmental and Occupational Exposure; Epigenetic Process; Exposure to; Gene Expression; Health; Heat Stress Disorders; Hepatic; Human; Immunologics; International; Interview; Journals; Kidney; Lead; Life Style; Liquid substance; Longitudinal Studies; Malignant Neoplasms; Mental Health; Mexico; Monitor; National Institute of Environmental Health Sciences; Neurologic; Nitrogen; Oils; Outcome; Peer Review; Persons; Petroleum; Population; Population Study; Preparation; Publications; Reporting; Research; Research Personnel; Resources; Safety; Scientist; Statistical Models; Subgroup; Substance abuse problem; Telephone Interviews; Toxin; Training; United States National Institutes of Health; Visit; Work; Writing; cohort; design; experience; falls; follow-up; interest; meetings; reproductive; respiratory

NIEHS is leading a National Institutes of Health (NIH) long term study looking at the potential health effects of the oil spill in various responder populations. During FY 2014, the GuLF STUDY (Gulf Long-term Follow-Up Study) completed its baseline recruitment efforts. In total, the GuLF STUDY has completed 32,608 telephone interviews and 11,193 in-person visits where biospecimens are collected. Biospecimens are banked in a long-term storage facility using liquid nitrogen where appropriate. NIEHS investigators are actively conducting the follow-up interviews for the GuLF STUDY. Additionally, NIEHS investigators are working on designing and implementing the clinical visit for the Biomedical Surveillance Sub-cohort of the GuLF STUDY. Data collection is expected to begin in the fall of 2014. In the meantime, NIEHS investigators are working to evaluate all of the available environmental and occupational exposure monitoring data in order to more completely characterize exposures in the study population. Ongoing statistical modeling will lead to the development of cleanup-task specific exposure matrices that will allow assignment of exposure estimates for volatile compounds and other exposures related to oil spill cleanup. Approaches and preliminary results from exposure characterization efforts were presented at national and international meetings. Cleaning and analysis of the baseline data has begun and we will be reporting findings at scientific meetings and writing up the results for publication in peer-reviewed journals.

NIEHS领导着美国国立卫生研究院（NIH）长期研究，研究在各种响应者人群中漏油的潜在健康影响。在2014财年，海湾研究（海湾长期随访研究）完成了基线招聘工作。总体而言，海湾研究已经完成了32,608次电话采访和11,193次亲自访问，其中收集了生物测量。在适当的情况下，使用液氮在长期存储设施中存放生物测量。 NIEHS调查人员正在积极进行海湾研究的后续访谈。此外，NIEHS的研究人员正在研究海湾研究的生物医学监视亚事业的临床访问。数据收集预计将于2014年秋季开始。 同时，NIEHS调查人员正在努力评估所有可用的环境和职业暴露监测数据，以便更彻底地表征研究人群中的暴露。正在进行的统计建模将导致开发清理任务特定的暴露矩阵，这将允许分配挥发性化合物的暴露估计以及与漏油清理有关的其他暴露。在国家和国际会议上提出了暴露表征工作的方法和初步结果。 对基线数据的清洁和分析已经开始，我们将在科学会议上报告调查结果，并在同行评审期刊上撰写出版物的结果。