Laboratory Animal Medicine and Translational Research Training for Veterinarians

兽医实验动物医学和转化研究培训

基本信息

批准号：
8660725
负责人：
THEA BRABB
金额：
$ 23.02万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-04-01 至 2016-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8660725
关键词：
Academia Address Aging American Animal Model Animal Welfare Animals Area Behavior Behavioral Behavioral Research Biology Biomedical Research Biotechnology Caring Clinical Collection Communities Complex Detection Educational process of instructing Ensure Environment Facility Designs Fisheries Funding Genetically Engineered Mouse Goals Growth Industry Infectious Disease Immunology Laboratories Laboratory Animal Medicine Laboratory Animals Literature Malignant Neoplasms Manuscripts Medicine Modeling Mus Operative Surgical Procedures Participant Pathology Peer Review Play Positioning Attribute Preventive Medicine Primates Publishing Qualifying Recording of previous events Research Research Ethics Research Methodology Research Training Resources Role Rotation Schools Science Scientist Training Transgenic Organisms Translational Research Universities Veterinarians Washington animal facility base career college comparative design disorder prevention meetings member model development nonhuman primate occupational health/safety programs research and development statistics

项目摘要

DESCRIPTION (provided by applicant): The steady growth of biomedical research involving the utilization of complex animal models has resulted in a need for highly trained laboratory animal veterinarians to manage, direct, and provide clinical and regulatory support. In addition, veterinarians are essential members of research teams due to their unique, comparative training in whole-animal biology, pathology, and surgery. The overall goal of this proposal is to train 3 additional post-graduate veterinarians in laboratory animal medicine and research methodology with the specific objective of preparing exceptional lab animal veterinarians for potential careers in academia, industry, and teaching. The duration of training will be 2 years of clinical laborator animal medicine, and 1 year of research methodology (3 years total training). The University of Washington (U.W.) is ideally positioned to accomplish these goals, due to its top-ranking in Federal Research Funding (#2 Funded Public University in 2010), associated Washington National Primate Research Center (WaNPRC) and School of Aquatic and Fishery Sciences, large local biotechnology community (Amgen Inc, ZymoGenetics Inc, etc), and long, 28 year history of successfully training laboratory animal veterinarians in a highly collaborative environment. The Specific Aims of this proposal are: (1) To train veterinary scientists in the biology, care, and treatment, detection, and prevention of disease in animals used in biomedical and behavioral research. We will utilize didactic courses and rotations through the U.W. Department Comparative Medicine (DCM) and WaNPRC- managed animal facilities, U.W. Office of Animal Welfare (OAW), Preventative Medicine and Occupational Health and Safety Programs, Transgenic Resources, and local biotechnology companies to provide in-depth Lab Animal Medicine training certified by the American College of Laboratory Animal Medicine (ACLAM); (2) To train veterinary scientists in biomedical research methodology, with emphasis on translational research involving mice or non-human primate models. Veterinary participants will perform hypothesis-based research in DCM or WaNPRC laboratories, with the goal of publishing a peer-reviewed manuscript to qualify for the ACLAM-board examination. Research training and didactic courses will focus on translational applications of utilizing genetically engineered mice (GEM) and non-human primates in Immunology, Infectious Disease, Behavior, Cancer, and Aging research. These Aims will ensure that U.W. Laboratory Animal Medicine graduates are highly-trained to become ACLAM-board certified; to address the Nation's biomedical, behavioral, and clinical needs; and to serve as successful collaborative research scientists.

描述（由申请人提供）：涉及复杂动物模型利用的生物医学研究的稳定增长导致需要训练有素的实验动物兽医来管理、指导和提供临床和监管支持。此外，兽医因其在整体动物生物学、病理学和外科手术方面接受过独特的、比较性的培训而成为研究团队的重要成员。该提案的总体目标是在实验动物医学和研究方法方面再培训 3 名研究生兽医，具体目标是为潜在的职业生涯培养优秀的实验动物兽医在学术界、工业界和教学界。培训期限为 2 年动物医学临床实验室和 1 年研究方法学（总共 3 年培训）。华盛顿大学 (U.W.) 在联邦研究资助方面名列前茅（2010 年资助公立大学排名第 2）、华盛顿国家灵长类动物研究中心 (WaNPRC) 和水产与渔业学院，因此处于实现这些目标的理想位置科学、当地大型生物技术社区（Amgen Inc、ZymoGenetics Inc 等），以及在高度协作的环境中成功培训实验动物兽医的 28 年悠久历史。该提案的具体目标是： (1) 在生物医学和行为研究中使用的动物疾病的生物学、护理、治疗、检测和预防方面培训兽医科学家。我们将通过华盛顿大学利用教学课程和轮换。比较医学系 (DCM) 和 WaNPRC 管理的动物设施，U.W.动物福利办公室 (OAW)、预防医学和职业健康与安全计划、转基因资源和当地生物技术公司提供经美国实验动物医学学院 (ACLAM) 认证的深入实验动物医学培训； (2) 培训兽医科学家的生物医学研究方法，重点是涉及小鼠或非人类灵长类动物模型的转化研究。兽医参与者将在 DCM 或 WaNPRC 实验室进行基于假设的研究，目标是发表经过同行评审的手稿，以获得参加 ACLAM 委员会考试的资格。研究培训和教学课程将侧重于利用基因工程小鼠 (GEM) 和非人类灵长类动物在免疫学、传染病、行为、癌症和衰老研究中的转化应用。这些目标将确保 U.W.实验动物医学毕业生经过严格培训，获得 ACLAM 委员会认证；满足国家的生物医学、行为和临床需求；并成为成功的合作研究科学家。