Laboratory Animal Medicine and Translational Research Training for Veterinarians

兽医实验动物医学和转化研究培训

基本信息

批准号：
8277549
负责人：
THEA BRABB
金额：
$ 12.07万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-04-01 至 2016-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8277549
关键词：
Academia Address Aging American Animal Model Animal Welfare Animals Area Behavior Behavioral Behavioral Research Biology Biomedical Research Biotechnology Caring Clinical Collection Communities Complex Detection Educational process of instructing Ensure Environment Facility Designs Fisheries Funding Genetically Engineered Mouse Goals Growth Industry Infectious Disease Immunology Laboratories Laboratory Animal Medicine Laboratory Animals Literature Malignant Neoplasms Manuscripts Medicine Modeling Mus Operative Surgical Procedures Participant Pathology Peer Review Play Positioning Attribute Preventive Medicine Primates Publishing Qualifying Recording of previous events Research Research Ethics Research Methodology Research Training Resources Role Rotation Schools Science Scientist Training Transgenic Organisms Translational Research Universities Veterinarians Washington animal facility base career college comparative design disorder prevention meetings member model development nonhuman primate occupational health/safety programs research and development statistics

项目摘要

DESCRIPTION (provided by applicant): The steady growth of biomedical research involving the utilization of complex animal models has resulted in a need for highly trained laboratory animal veterinarians to manage, direct, and provide clinical and regulatory support. In addition, veterinarians are essential members of research teams due to their unique, comparative training in whole-animal biology, pathology, and surgery. The overall goal of this proposal is to train 3 additional post-graduate veterinarians in laboratory animal medicine and research methodology with the specific objective of preparing exceptional lab animal veterinarians for potential careers in academia, industry, and teaching. The duration of training will be 2 years of clinical laborator animal medicine, and 1 year of research methodology (3 years total training). The University of Washington (U.W.) is ideally positioned to accomplish these goals, due to its top-ranking in Federal Research Funding (#2 Funded Public University in 2010), associated Washington National Primate Research Center (WaNPRC) and School of Aquatic and Fishery Sciences, large local biotechnology community (Amgen Inc, ZymoGenetics Inc, etc), and long, 28 year history of successfully training laboratory animal veterinarians in a highly collaborative environment. The Specific Aims of this proposal are: (1) To train veterinary scientists in the biology, care, and treatment, detection, and prevention of disease in animals used in biomedical and behavioral research. We will utilize didactic courses and rotations through the U.W. Department Comparative Medicine (DCM) and WaNPRC- managed animal facilities, U.W. Office of Animal Welfare (OAW), Preventative Medicine and Occupational Health and Safety Programs, Transgenic Resources, and local biotechnology companies to provide in-depth Lab Animal Medicine training certified by the American College of Laboratory Animal Medicine (ACLAM); (2) To train veterinary scientists in biomedical research methodology, with emphasis on translational research involving mice or non-human primate models. Veterinary participants will perform hypothesis-based research in DCM or WaNPRC laboratories, with the goal of publishing a peer-reviewed manuscript to qualify for the ACLAM-board examination. Research training and didactic courses will focus on translational applications of utilizing genetically engineered mice (GEM) and non-human primates in Immunology, Infectious Disease, Behavior, Cancer, and Aging research. These Aims will ensure that U.W. Laboratory Animal Medicine graduates are highly-trained to become ACLAM-board certified; to address the Nation's biomedical, behavioral, and clinical needs; and to serve as successful collaborative research scientists. PUBLIC HEALTH RELEVANCE: Veterinarians play a unique and critical role in biomedical research, by providing clinical and regulatory support, and by contributing as an essential part of scientific research teams. Currently, there is a significant shortage of Veterinarians trained in "Laboratory Animal Medicine". The University of Washington and the Washington National Primate Research Center propose to train 3 additional veterinarians in Laboratory Animal Medicine and Biomedical Research methodology.

描述（由申请人提供）：涉及复杂动物模型利用的生物医学研究的稳定增长导致需要训练有素的实验室动物兽医来管理，直接和提供临床和法规支持。此外，由于兽医在整个动物生物学，病理学和手术方面具有独特的比较培训，因此兽医是研究团队的重要成员。该提案的总体目标是培训3个在实验室动物医学和研究方法论的额外研究生兽医，其特定目标是为杰出的实验室动物兽医准备潜在的职业在学术界，工业和教学中。培训的持续时间将是2年临床实验室动物医学和研究方法学1年（总培训3年）。华盛顿大学（U.W.）的理想位置可以实现这些目标，这是因为它在联邦研究资金中排名第一（2010年＃2资助的公立大学），华盛顿国家灵长类动物和渔业科学学院和水上和渔业科学学院，以及大型本地生物技术社区（Amgen Incogentics Incin和28年度），并在Zymogentics Incin and Maginal Indial Introlians，Zymogentics Incin的高度悠久的历史，曾经是28年的悠久历史，环境。该提案的具体目的是：（1）在生物医学和行为研究中使用的动物中对生物学，护理和治疗，检测和预防疾病的兽医科学家进行培训。我们将利用U.W.的教学课程和轮换。部门比较医学（DCM）和U.W. WANPRC管理动物设施动物福利办公室（OAW），预防医学和职业健康与安全计划，转基因资源以及当地生物技术公司，以提供由美国实验室动物医学学院（ACLAM）认证的深入实验室动物医学培训；（2）培训兽医研究方法的兽医科学家，重点是涉及小鼠或非人类灵长类动物模型的翻译研究。兽医参与者将在DCM或WANPRC实验室中进行基于假设的研究，目的是出版经过同行评审的手稿，以便有资格参加Aclam-Board检查。研究培训和教学课程将集中于利用基因工程小鼠（GEM）和非人类灵长类动物的转化应用，以在免疫学，传染病，行为，癌症和衰老研究中使用。这些目标将确保U.W.实验室动物医学毕业生经过良好的培训，可以获得敏锐的认证；解决国家的生物医学，行为和临床需求；并充当成功的合作研究科学家。公共卫生相关性：兽医通过提供临床和监管支持，并作为贡献作为生物医学研究中的独特和关键作用科学研究团队。目前，在“实验动物医学”中接受过培训的兽医很大。华盛顿大学和华盛顿国家灵长类动物研究中心提议培训3位实验室动物医学和生物医学研究方法的另外三名兽医。