Chemistry and Mechanisms for Environmental Stress

环境压力的化学和机制

• 批准号: 8597820
• 负责人: Daniel C Liebler
• 金额: $ 1万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8597820
• 关键词: American; Award; Base Excision Repairs; Biocompatible Materials; Biology; Breathing; Carcinogenesis Mechanism; Chemicals; Chemistry; Disease; Education; Environmental Exposure; Environmental Health; Event; Exposure to; Feedback; Fostering; Funding; Future; Health; Human; Knowledge; Learning; Link; Metals; Mission; Motion; Nanotechnology; National Institute of Environmental Health Sciences; Paper; Participant; Pharmaceutical Preparations; Postdoctoral Fellow; Prevention; Process; Request for Applications; Research; Research Personnel; Role; Science; Scientist; Senior Scientist; Societies; Stress; Students; Systems Analysis; Technology; Toxic effect; Toxicology; Training; Translational Research; Travel; Work; austin; base; data integration; environmental agent; environmental chemical; experience; human disease; interdisciplinary approach; lectures; meetings; metabolomics; metal poisoning; nanotoxicology; posters; professor; programs; public health relevance; structural biology; symposium; tool

DESCRIPTION (provided by applicant): This application requests support for programming of the Division of Chemical Toxicology of the American Chemical Society (ACS) at its 246th National Meeting and Exposition in Indianapolis, IN from Sunday, September 8, 2013 to Wednesday, September 11, 2013. A unique feature of this ACS meeting is the broad theme of the national meeting, "Chemistry in Motion", which aligns highlighted events across the programming of all ACS divisions. The mission of the ACS Division of Chemical Toxicology is to promote the understanding of chemical mechanisms that contribute to disease processes and the toxicity of environmental agents, biomaterials, drugs and endogenous chemicals. The Division integrates work in chemistry, chemical biology, structural biology, toxicology, environmental health sciences and disease mechanisms. Three interrelated symposia are planned around the central theme "Chemistry and Mechanisms of Environmental Stress" and include invited talks by a diverse group of leading established and emerging scientists. The three symposia for which support is requested have especially strong relevance to the mission of the NIEHS. The first is entitled "Metabolomics in Toxicology" and highlights the implementation of global profiling technologies and data integration tools for systems analysis. The second is entitled "Chemistry and Biology of Metal Toxicity" and focuses on new mechanistic studies of metal-biomolecule interactions and their systemic effects. The third symposium session is entitled "Toxicology of Alternative Fuels" and focuses on inhalation toxicity mechanisms and carcinogenesis. A proffered paper session and a Young Investigators Symposium offer opportunities for young scientists in training to present their primary contributions and receive critical feedback from senior experts. Other highlights are a keynote lecture by Dr. Christopher Austin (Director of the National Center for Advancing Translational Sciences) and two high profile award symposia (the Founders Award and the Chemical Research in Toxicology Young Investigator Award). These sessions (supported by non-federal funds) will further enhance a strong overall program and provide diverse participants an outstanding representation of current work in the chemistry and biology of environmental exposures and disease.

描述（由申请人提供）：本申请要求支持美国化学学会化学毒理学（ACS）在其在印第安纳波利斯举行的第246届全国会议和博览会上进行编程，从2013年9月8日（星期日）到2013年9月11日（星期三）。ACS会议的独特特征是国民大会的广泛主题，“化学中的运动”，该活动是ACS的划分。 ACS化学毒理学司的使命是促进对有助于疾病过程和环境剂，生物材料，药物和内源性化学物质的毒性的化学机制的理解。该部门整合了化学，化学生物学，结构生物学，毒理学，环境健康科学和疾病机制的工作。计划围绕中心主题“化学和环境压力的机制”进行了三个相互关联的研讨会，其中包括一系列领先的建立和新兴科学家的邀请演讲。请求支持的三个研讨会与NIEHS的使命特别有意义。第一个标题为“毒理学代谢组学”，并突出了用于系统分析的全球分析技术和数据集成工具的实施。第二个标题为“金属毒性的化学和生物学”，并着重于金属生物分子相互作用及其系统作用的新机械研究。第三次研讨会的题为“替代燃料的毒理学”，重点是吸入毒性机制和癌变。一项提出的论文会议和年轻的调查人员研讨会为年轻科学家提供了培训的机会，以提出其主要贡献，并从高级专家那里获得关键反馈。其他亮点是克里斯托弗·奥斯汀（Christopher Austin）博士（国家前进科学中心主任）和两次知名奖颁奖典礼（创始人奖和《毒理学化学研究》年轻研究者奖）的主题演讲。这些会议（由非联邦基金的支持）将进一步增强强大的整体计划，并为各种参与者提供了当前在环境暴露和疾病的化学和生物学中工作的杰出代表。