Respiratory effects of e-cigarette use among youth: a prospective, longitudinal investigation

青少年使用电子烟对呼吸系统的影响：前瞻性纵向调查

基本信息

批准号：
10283173
负责人：
Alayna Pauline Tackett
金额：
$ 19.4万
依托单位：
OHIO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-12-17 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10283173
关键词：
Acute Adolescence Adolescent Adult Age Airway Resistance American Area Asthma Automobile Driving Behavior Chest Chronic Obstructive Pulmonary Disease Cross-Sectional Studies Data Development Devices Dose Ecological momentary assessment Electronic cigarette Environment Exhalation Frequencies Funding Health High School Student Home Impairment Inflammation Inhalation Investigation JUUL Knowledge Laboratories Link Longitudinal Studies Lung Lung diseases Measurement Measures Mentorship Methodology Methods Monitor Nicotine Nicotine Dependence Nitric Oxide Outcome Participant Patient Self-Report Pattern Perception Peripheral Persons Population Assessment of Tobacco and Health Postdoctoral Fellow Prevalence Regulation Reporting Research Research Personnel Resistance Respiratory physiology Role Sampling Smoker Societies Spirometry Time Tobacco Tobacco use Training United States National Institutes of Health Visit Youth design electric impedance electronic cigarette use electronic cigarette user innovation longitudinal design lung health novel pod mods polytobacco use prospective pulmonary function respiratory respiratory examination respiratory health response skills tobacco prevention tobacco products tobacco regulatory science tobacco user vaping

项目摘要

PROJECT ABSTRACT Electronic cigarettes (EC) remain the most commonly used product among high schoolers. Little is known about acute and longitudinal respiratory effects of ECs. This novel study will contribute critical knowledge needed to understand pulmonary functioning and respiratory effects among 150 youth who are exclusive-EC (N = 100) or never-users (N = 50; EC or other tobacco products), using a longitudinal, multimethod design. Youth will complete 5-laboratory assessments to provide a comprehensive assessment of respiratory health (airway reactivity and inflammation; pulmonary functioning). Further, we will incorporate EC user topography to assess the immediate acute effects of EC use on respiratory markers. Two weeks prior to laboratory assessments youth will complete daily EMA and spirometry assessments to examine how the frequency and quantity of EC use impairs acute pulmonary functioning. This Tobacco Regulatory K01 will provide much needed evidence regarding the immediate and longitudinal effects of EC use, while providing valuable training to a promising new investigator from leading experts in the field of tobacco regulatory science.

项目摘要电子烟（EC）仍然是高中生中最常用的产品。鲜为人知关于EC的急性和纵向呼吸作用。这项新颖的研究将有助于批判知识需要了解150名独家EC的青年中的肺功能和呼吸作用（n = 100）或从未使用的人（n = 50； EC或其他烟草产品），使用纵向的多途径设计。青年将完成5局评估，以提供呼吸健康的全面评估（气道反应性和炎症；肺功能）。此外，我们将将EC用户地形结合到评估EC使用对呼吸标记的急性影响。实验室前两周评估青年将完成每日EMA和肺活量测定评估，以研究频率和 EC使用的数量会损害急性肺功能。这种烟草监管K01将提供很多有关EC使用的直接和纵向影响的所需证据，同时提供有价值的培训来自烟草监管科学领域的主要专家的有前途的新调查员。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Appeal of e-cigarette flavors: Differences between never and ever use of combustible cigarettes.

电子烟口味的吸引力：从不使用和曾经使用过可燃香烟的区别。

DOI：
10.1016/j.drugalcdep.2023.109849
发表时间：
2023
期刊：
Drug and alcohol dependence
影响因子：
4.2
作者：
Tackett,AlaynaP;Dai,HongyingDaisy;Han,Dae-Hee;Vogel,ErinA;Coreas,SaidaI;Jafarzadeh,Nikki;GonzalezAnaya,MariaJ;Patel,Devaki;Peraza,Natalia;Mason,TylerB;Leventhal,AdamM
通讯作者：
Leventhal,AdamM

Feasibility and acceptability of remote procedures to study tobacco product use and respiratory health: an observational study.

DOI：
10.1136/bmjopen-2022-065962
发表时间：
2022-12-01
期刊：
BMJ open
影响因子：
2.9
作者：
通讯作者：

Adolescent Susceptibility to E-Cigarettes: An Update From the 2018 National Youth Tobacco Survey.

DOI：
10.1177/0890117120971121
发表时间：
2021-05
期刊：
American journal of health promotion : AJHP
影响因子：
0
作者：
Tackett AP;Keller-Hamilton B;Hébert ET;Smith CE;Wallace SW;Stevens EM;Johnson AL;Wagener TL
通讯作者：
Wagener TL

'Flavour ban approved': new marketing strategies from tobacco-free nicotine pouch maker Zyn.

DOI：
10.1136/tobaccocontrol-2021-057222
发表时间：
2023-04
期刊：
TOBACCO CONTROL
影响因子：
5.2
作者：
Tackett, Alayna P.;Barrington-Trimis, Jessica L.;Leventhal, Adam M.
通讯作者：
Leventhal, Adam M.

Youth use of e-cigarettes: Does dependence vary by device type?

DOI：
10.1016/j.addbeh.2021.106918
发表时间：
2021-08
期刊：
Addictive behaviors
影响因子：
4.4
作者：
Tackett AP;Hébert ET;Smith CE;Wallace SW;Barrington-Trimis JL;Norris JE;Lechner WV;Stevens EM;Wagener TL
通讯作者：
Wagener TL