Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer

增强亲密关系的夫妻对局限性前列腺癌的干预

• 批准号: 8700724
• 负责人: Sharon L Manne
• 金额: $ 11.33万
• 依托单位: RBHS -CANCER INSTITUTE OF NEW JERSEY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8700724
• 关键词: Address; Adverse effects; Attention; Back; Characteristics; Client satisfaction; Clinical; Communication; Couples; Data; Diagnosis; Distress; Educational process of instructing; Emotional; Erectile dysfunction; Extravasation; Family; Goals; Health; Individual; Intervention; Length; Malignant Neoplasms; Malignant neoplasm of prostate; Mediating; Modeling; Outcome; Participant; Patients; Pilot Projects; Play; Population Intervention; Problem Solving; Psychological adjustment; Quality of life; Randomized; Randomized Clinical Trials; Reporting; Research; Role; Sex Functioning; Staging; Surveys; Testing; Time; Uncertainty; Work; base; brief intervention; communication behavior; comparative efficacy; improved; innovation; intimate behavior; men; oncology; psychologic; psychological distress; psychosocial; satisfaction; self esteem; skills; stress management; treatment as usual; treatment effect; urinary

DESCRIPTION (provided by applicant): The diagnosis and treatment of localized prostate cancer can reduce the quality of life for both patient and partner. Our preliminary studies as well as the work of others suggest that couples' communication and intimacy play a role in the psychological and relationship functioning of both patient and partner. These results suggest that enhancing intimacy via improvements in the communication strategies couples utilize may be a prime target for psychological intervention. We have developed an Intimacy- Enhancing Couples' Intervention (IEC) and tested it against a Usual care control (UC) in a small randomized clinical trial. The primary goal of IEC is to teach couples relationship-enhancing communication skills and bolster relationship intimacy. Preliminary results suggested that IEC reduced patient and partner distress and improved communication and intimacy. The goal of the proposed study is to conduct a larger scale trial to evaluate IEC's efficacy against an attention control (a General Health and Wellness Intervention; GHW) and to evaluate moderators and mechanisms for the treatment's effects. 469 men diagnosed with localized prostate cancer and their partners will be randomly assigned to IEC, GHW, or UC. Participants will complete surveys pre-intervention, 5 weeks, 12 weeks, and six months post-baseline. The aims are: 1) To evaluate the impact of an IEC versus a GHW and UCl on patient and partner psychological and relationship outcomes. 2) To determine whether relationship length, pre-intervention marital satisfaction, and men's pre-intervention traditional masculinity moderate the effects of IEC on couples' psychological and relationship outcomes. IEC will have a stronger impact on patient and partner psychological and relationship functioning among patients and partners married a longer period of time, patients and partners reporting lower pre-intervention levels of marital satisfaction, and among patients reporting higher levels of traditional masculinity; 3) To evaluate whether IEC has an effect on couples' communication and intimacy when compared with GHW and UC, and to determine whether changes in relationship communication and intimacy mediate changes in couples' psychological and relationship outcomes.

描述（由申请人提供）：局部前列腺癌的诊断和治疗可以降低患者和伴侣的生活质量。我们的初步研究以及其他人的工作表明，夫妻的沟通和亲密关系在患者和伴侣的心理和关系功能中起作用。这些结果表明，通过改进沟通策略夫妇使用的沟通策略增强亲密关系可能是心理干预的主要目标。我们已经开发了一种亲密的增强夫妇的干预（IEC），并在一项小型随机临床试验中针对通常的护理控制（UC）进行了测试。 IEC的主要目标是教夫妇增强关系的沟通技巧和增强关系亲密关系。初步结果表明，IEC减少了患者和伴侣的困扰，并改善了沟通和亲密关系。拟议的研究的目的是进行大规模试验，以评估IEC针对注意力控制的功效（一般健康和健康干预； GHW），并评估主持人和机制以实现治疗的影响。 469名被诊断患有局部前列腺癌的男性及其伴侣将随机分配给IEC，GHW或UC。参与者将完成干预前的调查，5周，12周和六个月后。目的是：1）评估IEC与GHW和UCL对患者和伴侣心理和关系结果的影响。 2）确定关系长度，干预前的婚姻满意度以及男性的干预前传统男性气质是否适应IEC对夫妻心理和关系结果的影响。 IEC将对患者和伴侣的心理和关系功能产生更大的影响，与患者和伴侣之间的关系更长，患者和伴侣报告的婚姻前婚前满意度较低，以及报告传统男性气质水平较高的患者中； 3）评估与GHW和UC相比，IEC是否对夫妻的交流和亲密关系有影响，并确定关系交流和亲密关系的变化是否介导了夫妻的心理和关系结果的变化。