Visual Science Training Grant

视觉科学培训补助金

• 批准号: 8463203
• 负责人: Z JIMMY ZHOU
• 金额: $ 14.83万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8463203
• 关键词: Grant; Training; vision science

Program Director/Principal Investigator (Last, First, Middle): Zhou, Z. Jimmy Abstract This application proposes to provide integrative training in visual science research at Yale University School of Medicine, with a special emphasis on visual neuroscience. The goal of this program is to foster interdisciplinary approaches to visual neuroscience that will interface with molecular genetics and clinical medicine with respect to development, organization, function and dysfunction of the eye and the central visual system. Twelve faculty preceptors from five basic and clinical departments participate in this multidisciplinary program. These faculty members lead vibrant vision research programs in a vision research community at Yale that has undergone an exciting phase of revitalization and expansion, and that has attracted an increasing number of outstanding graduate students and postdoctoral fellows. The proposed training program offers both depth and breadth. The depth derives from its substantive focus on the neurobiology of the eye and the visual system. The breadth of the program derives from the diversity of approaches, spanning molecular, developmental, systems, cognitive and theoretical neuroscience, as well as from the range of experimental models used in these studies, spanning zebrafish, rodents, and primates. Faculty interests range from retinal development and degeneration, retinal physiology and circuits to visual cortical function and visual behavior. Methodologies include cloning; cell culture; immunocytochemistry; in situ hybridization; gene transfection and transgenic technology, electron and two photon microscopy; patch-clamp and multielectrode recording; electroretinograph, calcium and other forms of optical imaging; biochemistry and molecular analyses; psycho- pharmacology; rodent, monkey and human behavior; in vivo extracellular recording in behaving animals; and fMRI and PET imaging in human subjects. Two predoctoral and two postdoctoral positions are requested. Trainees will be selected from a variety of backgrounds in biological sciences on the basis of their potential for excellence and leadership in research by an Executive Committee. Mentors are Ph.D.s and M.D.s. with NEI and other NIH institute grants or NEI related research foci. Training includes coursework, intensive research apprentice-ship, structured seminar programs, laboratory and departmental presentations of research progress, and instructions on responsible research conduct. PHS 398/2590 (Rev. 06/09) Page Continuation Format Page

项目总监/首席调查员（最后，第一，中间）：Zhou，Z。Jimmy 抽象的 该申请建议在耶鲁大学提供视觉科学研究的综合培训 医学院，特别强调视觉神经科学。该计划的目标是培养 视觉神经科学的跨学科方法，将与分子遗传学和临床接触 关于眼睛和中央视觉的发展，组织，功能和功能障碍的医学 系统。来自五个基本和临床部门的十二位教职员工参与了这个多学科 程序。这些教职员工领导着充满活力的视力研究计划 耶鲁大学经历了激动人心的振兴和扩张阶段，这吸引了 杰出的研究生和博士后研究员越来越多。拟议的培训计划 提供深度和广度。深度源自其对眼睛的神经生物学的实质性和 视觉系统。该程序的广度来自跨越分子的方法的多样性， 发展，系统，认知和理论神经科学以及实验范围 这些研究中使用的模型，涵盖斑马鱼，啮齿动物和灵长类动物。教师利益范围从视网膜 发育和变性，视网膜生理和视觉皮质功能和视觉行为的回路。 方法包括克隆；细胞培养；免疫细胞化学；原位杂交；基因转染和 转基因技术，电子和两个光子显微镜；贴片夹和多电极记录； 电视图，钙和其他形式的光学成像；生物化学和分子分析；心理 药理;啮齿动物，猴子和人类行为；行为动物中的体内细胞外记录；和 fMRI和人类受试者的宠物成像。 请求两个主要的和两个博士后职位。学员将从各种各样的 生物科学的背景是基于他们在研究中的卓越潜力和领导力的基础上通过 执行委员会。导师是博士学位和M.D.S.与NEI和其他NIH Institute赠款或NEI相关 研究焦点。培训包括课程工作，密集研究学徒职位，结构化研讨会计划， 研究进度的实验室和部门演讲，以及负责任研究的指示 执行。 PHS 398/2590（修订版06/09）页面延续格式页面