Clincal and Translational Science Award

临床和转化科学奖

基本信息

批准号：
9078070
负责人：
REZA NONE SHAKER
金额：
$ 70.02万
依托单位：
MEDICAL COLLEGE OF WISCONSIN
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2015-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9078070
关键词：
Address Ally Area Award Biomedical Engineering Clinical Clinical Research Clinical Sciences Communities Country Dentistry Diagnostic Discipline Discipline of Nursing Education Engineering Environment Fostering Goals Health Health Personnel Healthcare Home environment Hospitals Industry Institutes Institution Instruction Leadership Measures Medical Medical center Modeling Pediatric Hospitals Preventive Public Health Recording of previous events Research Research Infrastructure Research Personnel Resources Rest Role Schools Scientist Social Sciences Transcend Translating Translational Research Translations United States National Institutes of Health Universities Wisconsin Work authority base bench to bedside biomedical resource clinical practice collaborative environment effective therapy empowered experience improved innovation medical schools novel programs social

项目摘要

The National institutes of Health's RFA for Clinical and Translational Science Awards has catalyzed the efforts of academic medical institutions to remove impediments to the translation of fundamental discoveries into better health for our citizens and rectify shortages within the clinical and translational workforce. This proposal of the Clinical and Translational Science Institute of Southeast Wisconsin is tailored to the needs and resources of the biomedical enterprise in the region and offers a novel and transformative plan to achieve the above mentioned goals. Building on the long collaborative history among the major academic and healthcare institutions in our area, we have constructed a unique academic-community partnership comprised of the Medical College of Wisconsin, University of Wisconsin-Milwaukee, Marquette University, Milwaukee School of Engineering, Froedtert Hospital, Children's Hospital of Wisconsin, Zablocki VA Medical Center and BloodCenter of Wisconsin, set in the milieu of a large urban community with remarkable ethnic and social diversity. Our proposal brings together the various resources of the partner institutions to identify and address the obstacles that impede the conduct of clinical and translational research in the region. The transfonning environment of our CTSI focuses on the interdependency and interrelationship of our research teams and the relationship of the key functions to the rest of the CTSA in their integrating, enabling and effecting roles. To accomplish this transfonnation, we propose (and have begun to implement during the pre-award years) 1) To develop a distinct "Academic Home" for the discipline of clinical and translational science - the Clinical and Translational Science Institute (CTSI) - which transcends intra-and inter-institutional barrier, empowers experienced leadership to have the authority and resources to promote, facilitate, coordinate and foster the continuum of translational research from bench to bedside (Tl), to clinical practices (T2), and to our communities (T3); 2) To increase the number of investigators participating in clinical research through innovative programs within the CTSI; 3) To develop, align, and coordinate infrastructure across institutions to provide our scientists with the resources required for Clinical and Translational research; and 4) To engage clinical practices and the community in research h that enhances public health. Our Community Engagement program is an MCW strength. We will build on an existing network of the Healthier Wisconsin Partnership Program (HWPP) and expertise and resources of our partners in medical, biomedical engineering, dentistry, nursing, social sciences and allied health disiciplines to implement novel community based (T3) research programs. We believe our CTSA model is transferable to other similarly-sized academic research communities across the country. RELEVANCE (See instructions): Better preventive measures, more accurate diagnostics, and more effective therapies are badly needed to improve the health of our citizens. This application provides a novel and comprehensive mechanism to address these needs through research and education. It creates a borderless, collaborative environment in SE Wisconsin for biomedical researchers, healthcare providers, educators, citizens, and industry to work together synergistically and translate the fundamental discoveries into better health for our citizens.

美国国立卫生研究院的 RFA 临床和转化科学奖促进了以下方面的努力学术医疗机构消除将基本发现转化为更好成果的障碍保障我们公民的健康并纠正临床和转化劳动力的短缺。这项提议的威斯康星州东南部的临床和转化科学研究所是根据以下领域的需求和资源量身定制的：该地区的生物医药企业，并提供了一个新颖的变革性计划来实现上述目标目标。基于我们地区主要学术和医疗机构之间的悠久合作历史，我们建立了由威斯康星医学院组成的独特的学术界合作伙伴关系，威斯康星大学密尔沃基分校、马凯特大学、密尔沃基工程学院、Froedtert 医院、威斯康星州儿童医院、Zablocki VA 医疗中心和威斯康星州血液中心位于具有显着种族和社会多样性的大型城市社区。我们的建议汇集了各种伙伴机构的资源，以查明和解决阻碍临床和治疗开展的障碍该地区的转化研究。我们 CTSI 的转型环境侧重于相互依赖我们研究团队的相互关系以及关键职能与 CTSA 其余部分的关系他们的整合、促进和影响作用。为了实现这一转变，我们提出（并已在颁奖前几年开始实施）1) 为临床和转化科学学科建立一个独特的“学术家园”——临床和转化科学中心转化科学研究所 (CTSI) - 超越机构内和机构间的障碍，赋予经验丰富的领导者拥有权力和资源来促进、促进、协调和培育从实验室到临床 (Tl)、到临床实践 (T2) 以及我们的社区的转化研究的连续体（T3）； 2）通过创新项目增加参与临床研究的研究者数量在 CTSI 内； 3) 开发、调整和协调跨机构的基础设施，为我们的科学家提供服务拥有临床和转化研究所需的资源； 4) 参与临床实践和社区参与增强公共卫生的研究。我们的社区参与计划是 MCW 的优势。我们将建立在健康威斯康星州合作伙伴计划 (HWPP) 的现有网络和专业知识的基础上我们的合作伙伴在医疗、生物医学工程、牙科、护理、社会科学和联合健康领域的资源实施新颖的基于社区（T3）的研究计划的学科。我们相信我们的 CTSA 模型是可转移到全国其他类似规模的学术研究团体。相关性（参见说明）：迫切需要更好的预防措施、更准确的诊断和更有效的治疗方法改善我们公民的健康。该应用程序提供了一种新颖且全面的机制来解决通过研究和教育来满足这些需求。它在威斯康星州东南部创建了一个无边界的协作环境供生物医学研究人员、医疗保健提供者、教育工作者、公民和行业协同合作并将这些基本发现转化为我们公民的更好健康。