Portable hand-held non-mydriatic retinal camera

便携式免散瞳眼底照相机

• 批准号: 8453271
• 负责人: Peter N Soliz
• 金额: $ 18.91万
• 依托单位: VISIONQUEST BIOMEDICAL, LLC
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-02-01 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8453271
• 关键词: Adoption; Affect; Age; American; Applications Grants; Area; Caring; Clinic; Clinical; Collaborations; Consult; Consultations; Contracts; Development; Device or Instrument Development; Devices; Diabetes Mellitus; Diabetic Retinopathy; Diet Habits; Disease; Doctor of Philosophy; Environment; Exercise; Eye; Eye diseases; Family; Fundus; Glaucoma; Goals; Hand; Healthcare; Image; Impairment; Individual; Institutes; International; Laboratories; Lead; Legal patent; Marketing; Measures; Medical; Medical Device; Metric; Mydriatics; Names; Non-Insulin-Dependent Diabetes Mellitus; Nurses; Ophthalmologist; Optics; Overweight; Phase; Physician Executives; Physicians; Population; Primary Care Physician; Principal Investigator; Production; Recording of previous events; Resolution; Retina; Retinal; Rural; Safety; Services; Solutions; South Texas; Staging; System; Systems Development; Technology; Telemedicine; Testing; Time; Training; Travel; United States National Institutes of Health; Vision; Work; adaptive optics; age related; base; commercialization; cost; design; diabetic; disease diagnosis; ergonomics; experience; human subject; meetings; operation; portability; prevent; programs; prototype; public health relevance; screening; success

DESCRIPTION (provided by applicant): According to the National Institutes of Health, there are more than 80 million people in the US who suffer from a potentially sight-threatening disease. Doctors see seven to eight million new cases of eye disease annually. More than two million Americans age 50 and older have advanced AMD, the stage that can lead to severe vision impairment and 10 million have early or intermediate AMD. Glaucoma affects more than 2.3 million Americans age 40 and older. Another two million individuals with glaucoma are undiagnosed. Diabetes cases in the US and throughout the world have been on the rise. Poor eating habits and lack of exercise, factors which contribute to type 2 diabetes, have led to an increasingly overweight population. According to the International Diabetes Federation, there are 285 million cases of diabetes in the world as of 2010. For the type 2 diabetics, 50% will develop diabetic retinopathy within 15 years of disease diagnosis. Regular eye disease screening is necessary to prevent the progression of eye diseases to advanced, sight-threatening stages. The objective of this project is to develop and test a low-cost, hand-held, non-mydriatic retinal camera for widespread applications, including teleretinal screening for eye diseases such as diabetic retinopathy, glaucoma, and age-related ocular diseases. The proposed camera fills an important unmet need: low-cost (under $1,500 cost of goods); small footprint (principally a hand-held device); and easy to use (ergonomically designed for operation by a minimally trained medical technician or nurse). Introducing this technology to a clinic environment will allow underserved individuals to receive regular eye screenings without traveling to an eye care professional. To meet this goal, our proposal has two aims. First, we will produce a prototype of the low-cost, hand-held, non-mydriatic camera, which will be based on an early prototype of a mydriatic camera that was developed, and for which early testing has shown significant functionality. The design is based on low-cost, off-the-shelf components that can be assembled easily for a high- volume market. Second, we will test this camera in a screening or clinic environment. Making the camera ergonomically suitable for use by a minimally trained individual will be the goal of this aim. Quantitative analysis will be performed as to field of view, resolution, and safety.

描述（由申请人提供）：根据美国国立卫生研究院的数据，美国有超过 8000 万人患有潜在威胁视力的疾病。医生每年都会发现七到八百万新的眼病病例。超过 200 万 50 岁及以上的美国人患有晚期 AMD，这一阶段可能导致严重的视力损害，其中 1000 万患有早期或中期 AMD。青光眼影响超过 230 万 40 岁及以上的美国人。另有 200 万青光眼患者尚未确诊。美国和世界各地的糖尿病病例一直在增加。不良的饮食习惯和缺乏运动是导致 2 型糖尿病的因素，导致超重人口日益增多。据国际糖尿病联盟统计，截至2010年，全球有2.85亿糖尿病病例。对于2型糖尿病患者，50%将在诊断后15年内发展为糖尿病视网膜病变。定期进行眼部疾病筛查对于防止眼部疾病进展至威胁视力的晚期阶段是必要的。该项目的目标是开发和测试一种低成本、手持式、免散瞳视网膜相机，以广泛应用，包括对糖尿病视网膜病变、青光眼和与年龄相关的眼部疾病等眼部疾病进行远程视网膜筛查。拟议的相机满足了一个重要的未满足的需求：低成本（商品成本低于 1,500 美元）；占地面积小（主要是手持设备）；且易于使用（符合人体工程学设计，适合由经过最低限度培训的医疗技术人员或护士操作）。将这项技术引入诊所环境将使服务不足的个人能够定期接受眼科检查，而无需前往眼科护理专业人员处。为了实现这一目标，我们的提案有两个目标。首先，我们将 生产低成本、手持式、免散瞳相机的原型，该原型将基于已开发的散瞳相机的早期原型，并且早期测试已显示出重要的功能。该设计基于低成本、现成的组件，可以轻松组装以适应大批量市场。其次，我们将在筛查或诊所环境中测试这款相机。该目标的目标是使相机符合人体工程学，适合受过最低限度培训的人员使用。将针对视野、分辨率和安全性进行定量分析。