Mechanisms of Health and Disease at the Behavioral-Biomedical Interface

行为-生物医学界面的健康与疾病机制

• 批准号: 9569948
• 负责人: SUSAN K LUTGENDORF
• 金额: $ 17.18万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9569948
• 关键词: Behavioral; Disease; Health

Abstract The interface of behavioral and biomedical sciences is one of the most vibrant frontiers of science today. The overarching objective of our NIGMS-funded predoctoral Training Program, Mechanisms of Health and Disease at the Behavioral-Biomedical Interface, is to train the next generation of diverse behavioral science researchers to utilize rigorous biomedical methodologies and conceptual frameworks that stretch the boundaries of their thinking and research to position them to make transformative breakthroughs in addressing issues of health and disease. The program provides predoctoral behavioral science students in the University of Iowa Department of Psychological and Brain Sciences with an integrated program of coursework and laboratory experiences. These include (1) broad-based training in the fundamentals of behavioral science including rigor and transparency, quantitative methodology and experimental design, responsible conduct of research, and key issues in health psychology, clinical psychology, and neuroscience; (2) In-depth training in pathophysiology and specific biomedical research areas (including conceptual framework, driving hypotheses, and laboratory techniques); and (3) guidance and mentoring for development and implementation of an innovative independent research program that spans both behavioral and biomedical science. The Training Program focuses on two themes: Lifespan Brain Health and Psychobiology of Chronic Disease and Women's Health. Behavioral mentors are from Psychological and Brain Sciences; Biomedical mentors come from the Colleges of Medicine, Public Health, and Nursing. Over the first 3 years of NIGMS support, we have developed a highly successful Training Program that has had far-reaching and lasting influences on a group of committed and enthusiastic students. We have used the support slots provided by the T32 grant and the two matching slots provided by the Graduate College of the U. of Iowa to recruit outstanding diverse students and to provide a catalyst for this program, which has matured into a vibrant setting for scientific exchange between behavioral science students and biomedical mentors and their labs. Since the start of the program, in addition to our 8 T32 funded students, we have had 25 additional trainees take advantage of the Training Program, including 7 diverse students. We have developed a program of seminars and retreats, featuring professional development, science communication, manuscript and grant writing, and discussions of cutting-edge research at the Behavioral-Biomedical interface. In sum, the NIGMS support for 4 students/year has returned large dividends on the investment. This renewal application requests the continuation of 4 slots per year so that we can build upon our strong foundation to continue this innovative program for another funding cycle. The program is highly relevant to public health because training at the behavioral-biomedical interface will enable these scientists to innovatively address mechanisms that influence health and disease.

抽象的 行为科学和生物医学科学的结合是当今最具活力的科学前沿之一。 我们的 NIGMS 资助的博士前培训计划的总体目标是健康机制和 行为-生物医学界面的疾病，旨在训练下一代多样化的行为 科学研究人员利用严格的生物医学方法和概念框架 他们的思维和研究的界限，使他们能够在以下领域取得变革性突破 解决健康和疾病问题。该计划为行为科学博士前学生提供 爱荷华大学心理与脑科学系的综合课程 课程作业和实验室经验。其中包括 (1) 基础知识方面的广泛培训 行为科学，包括严谨性和透明度、定量方法和实验设计， 负责任的研究行为以及健康心理学、临床心理学和健康心理学的关键问题 神经科学； （2）病理生理学和特定生物医学研究领域（包括 概念框架、驱动假设和实验室技术）； (3) 指导和指导 开发和实施跨越两个领域的创新独立研究计划 行为和生物医学科学。培训计划重点关注两个主题： 终生大脑健康 以及慢性病和妇女健康的心理生物学。行为导师来自心理学 和脑科学；生物医学导师来自医学院、公共卫生学院和护理学院。 在 NIGMS 支持的前 3 年里，我们制定了非常成功的培训计划， 对一群忠诚而热情的学生产生了深远而持久的影响。我们有 使用 T32 补助金提供的支持插槽和研究生提供的两个匹配插槽 爱荷华大学学院招募优秀的多元化学生并为该计划提供催化剂， 它已经成熟成为行为科学学生和学生之间科学交流的充满活力的环境 生物医学导师及其实验室。自该计划启动以来，除了我们资助的 8 个 T32 学生们，我们还有 25 名额外的学员参加了培训计划，其中包括 7 名不同的学员 学生。我们制定了一系列研讨会和静修计划，以专业发展为特色， 科学传播、手稿和资助写作以及前沿研究的讨论 行为生物医学界面。总之，NIGMS 对 4 名学生/年的支持已得到大量回报 投资股息。此续订申请要求每年延续 4 个名额，以便 我们可以在我们坚实的基础上继续这一创新计划，进入下一个融资周期。 该计划与公共卫生高度相关，因为行为生物医学界面的培训将 使这些科学家能够创新地解决影响健康和疾病的机制。