NEI Mentored Clincial Scientist Development Program Award (K12)

NEI 指导临床科学家发展计划奖 (K12)

• 批准号: 8513331
• 负责人: SCOTT W COUSINS
• 金额: $ 68.26万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8513331
• 关键词: Academic Medical Centers; Academic Training; Applications Grants; Area; Clinic; Clinical Oncology Supplement (K12); Clinical Research; Clinical Trials; Country; Educational Curriculum; Educational process of instructing; Ethics; Experimental Models; Faculty; Funding; Generations; Genetic; Genomics; Goals; Grant; Health Policy; Individual; Institution; International; Lead; Leadership; Learning; Mentors; Mentorship; Ophthalmologist; Ophthalmology; Outcome; Pathologist; Pathology; Patients; Peer Review Grants; Positioning Attribute; Preparation; Program Development; Proteomics; Recruitment Activity; Research; Residencies; Resources; Role; Scientist; Tissues; Training; Universities; Writing; base; bench to bedside; career; design; didactic education; eye center; member; next generation; programs; responsible research conduct; skills; statistics; translational medicine

This is an institutional training grant proposal to educate the next generation of clinician-scientists for academic positions in Ophthalmology. For over 38 years, the Duke University Eye Center (DUEC) has been a national leader in training academic Ophthalmologists. The earliest generations of these trainees now serve in numerous leadership positions in academic medical centers across the country and abroad. They have roles as Deans, Department Chairs, and faculty members and serve as mentors for academicians. We propose to continue this tradition through an intensive program designed to provide the guidance, resources, and didactic teaching necessary to produce clinician-scientists for academic positions in Ophthalmology. We plan to select two trainees each year after their completion of a residency in Ophthalmology or Pathology for an intense 3 year educational program that will lead to independent peer-reviewed grant funding and a faculty position in an academic institution. The trainees will undergo an intensive didactic curriculum combined with a close mentorship by senior faculty at Duke University. Each trainee will receive mandatory training in areas of clinical research, genetics, statistics, scientific writing, grant preparation, ethics, and the responsible conduct of research. Each trainee will participate in significant original research and learn the essential skills to develop a successful and independent academic career. Additional aspects of the curriculum of each trainee will be tailored by the program director and lead mentor based upon the selected primary research track and his/her skills, background and career goals. We propose five primary research tracks: (1) translational medicine and clinical trials, (2) clinics and bedside to the bench, (3) Ophthalmic genomics and proteomics, (4) ophthalmic pathology, (5) outcomes and health policy. Because of an international shortage of Ophthalmic Pathologists we will attempt to recruit and appropriate individuals for a research career involving the use of ocular tissues derived from patients and experimental models.

这是一项机构培训赠款建议，旨在教育下一代临床医生的学术职位。在超过38年的时间里，杜克大学眼中中心（DUEC）一直是培训学术眼科医生的国家领导者。这些受训者的最早几代人现在在全国和国外的学术医疗中心担任许多领导职务。他们担任院长，部门主席和教职员工的角色，并担任院士的导师。我们建议通过一个密集的计划来继续这一传统，旨在提供所必需的指导，资源和教学教学，以创造临床医生科学家在眼科中的学术职位。我们计划在一项激烈的3年教育计划中完成眼科或病理学居住后，每年选择两名学员，这将导致独立的同行评审赠款资金和学术机构的教职员工职位。学员将接受一项密集的教学课程，并由杜克大学高级教师的密切指导。每个学员将在临床研究，遗传学，统计，科学写作，授予准备，道德规范和负责任的研究领域接受强制性培训。每个学员将参与重要的原始研究，并学习发展成功和独立的学术职业的基本技能。每个学员的课程的其他方面将由计划主任和首席导师根据所选的主要研究轨道以及他/她的技能，背景和职业目标量身定制。我们 提出了五个主要的研究轨道：（1）转化医学和临床试验，（2）替补席的诊所和床边，（3）眼科基因组学和蛋白质组学，（4）眼科病理学，（5）结果和健康政策。由于眼科病理学家的国际短缺，我们将尝试招募和适当的个人作为研究职业，涉及使用来自患者和实验模型的眼组织。

项目成果

Health services research and how it can inform the current state of ophthalmology.

卫生服务研究及其如何为眼科现状提供信息。

• DOI: 10.1016/j.ajo.2010.07.006
• 发表时间: 2010
• 期刊: American journal of ophthalmology
• 影响因子: 4.2
• 作者: Muir,KellyW;Bosworth,HaydenB;Lee,PaulP
• 通讯作者: Lee,PaulP

Glaucoma Blindness at a Tertiary Eye Care Center.

• DOI: 10.18043/ncm.76.4.211
• 发表时间: 2015-09
• 期刊: North Carolina medical journal
• 作者: Stone JS;Muir KW;Stinnett SS;Rosdahl JA
• 通讯作者: Rosdahl JA

Acquired bilateral myelinated retinal nerve fibers after unilateral optic nerve sheath fenestration in a child with idiopathic intracranial hypertension.

特发性颅内高压患儿单侧视神经鞘开窗术后获得双侧有髓鞘视网膜神经纤维。

• DOI: 10.1016/j.jaapos.2012.08.006
• 发表时间: 2012
• 期刊: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
• 作者: Prakalapakorn,SasapinG;Buckley,EdwardG
• 通讯作者: Buckley,EdwardG

Glaucoma patients' trust in the physician.

• DOI: 10.1155/2009/476726
• 发表时间: 2009
• 期刊: Journal of ophthalmology
• 影响因子: 1.9
• 作者: Muir KW;Santiago-Turla C;Stinnett SS;Herndon LW;Allingham RR;Challa P;Lee PP
• 通讯作者: Lee PP

Retinal Artery-Vein Classification via Topology Estimation.

• DOI: 10.1109/tmi.2015.2443117
• 发表时间: 2015-12
• 期刊: IEEE transactions on medical imaging
• 影响因子: 10.6
• 作者: Estrada R;Allingham MJ;Mettu PS;Cousins SW;Tomasi C;Farsiu S
• 通讯作者: Farsiu S