Mutant Mouse Regional Resource Center Annual Meeting.

突变小鼠区域资源中心年会。

• 批准号: 8546461
• 负责人: TERRY R MAGNUSON
• 金额: $ 1.72万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-18 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8546461
• 关键词: Address; Advisory Committees; Archives; Atlases; Beta Cell; Biological Preservation; Biomedical Research; California; Cellular biology; Collection; Communication; Communities; Country; Defect; Development; Disease susceptibility; ES Cell Line; Electronic Mail; Ensure; Equipment and supply inventories; Funding; Gene Expression; Genes; Genetic; Genetic Models; Genetically Engineered Mouse; Genomics; Goals; Growth; Health; Human; Human Resources; Individual; Informatics; Institution; Life; Link; Medicine; Metric; MicroRNAs; Missouri; Modeling; Monitor; Mouse Strains; Mus; Mutagenesis; Mutant Strains Mice; National Center for Research Resources; Nature; Nervous system structure; Neurosciences; North Carolina; Pathway interactions; Performance; Persons; Pharmacologic Substance; Pigmentation physiologic function; Policies; Principal Investigator; Production; Request for Proposals; Research; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Resources; Services; Strategic Planning; Subgroup; Technology; Teleconferences; The Jackson Laboratory; Time; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; comparative; cost; human disease; improved; meetings; member; model development; mouse model; mutant; mutant mouse model; operation; organizational structure; programs; promoter; repository; success; symposium; tool

DESCRIPTION (provided by applicant): The Mutant Mouse Regional Resource Centers (MMRRC) were created in 1999 to meet the increasing demand for a centralized resource for archiving and distributing genetically modified mouse strains to the research community. The Centers are part of a multi-institutional, nationally distributed resource program with four repositories located strategically in the Western (University of California-Davis), Central (University of Missouri), and Eastern (University of North Carolina-Chapel Hill and The Jackson Laboratory) USA, and a single, centralized Informatics, Coordination and Service Center (ICSC at University of California- Davis) that provides a single interface to the scientific user community. The common goal is to provide mouse model resources and research support services to the research community. In addition, the centers use their expertise to research and implement new related technologies. As the production of genetically engineered mice has increased dramatically, the centers have expanded to include an inventory of over 32,527 mutant and genetically engineered mouse strains maintained as live colonies, cryopreserved germplasm, and embryonic stem (ES) cell lines and have filled ~4,080 orders from ~3550 investigators at over 2000 institutions worldwide. In a nationally distributed, multi-institutional program with a common goal, there is a critical need for high level of coordinated communication. Day-to day operations, management and development of short term strategies are discussed by email as well as in monthly teleconferences between key personnel at all of the Centers and NIH program staff and periodic teleconferences for subgroups addressing specific Center needs. However, there is no real substitute for regular in-person meetings; therefore, this proposal requests funding for the MMRRC to organize and plan annual meetings over the coming five year period. Such annual meetings are critical to 1) provide sufficient time and face-to-face interactions to review progress and discuss short- and long-term planning strategies to ensure that the MMRRC Program continues to evolve to serve the rapidly evolving needs of the scientific community and 2) provides a venue for showcasing the MMRRC program to NIH officers and other relevant members of the scientific community and inviting their input.

描述（由申请人提供）：1999年创建了突变的小鼠区域资源中心（MMRRC），以满足对归档和分配转基因小鼠菌株的集中资源需求的不断增长的需求。 The Centers are part of a multi-institutional, nationally distributed resource program with four repositories located strategically in the Western (University of California-Davis), Central (University of Missouri), and Eastern (University of North Carolina-Chapel Hill and The Jackson Laboratory) USA, and a single, centralized Informatics, Coordination and Service Center (ICSC at University of California- Davis) that provides a single interface to the scientific user community.共同的目标是向研究社区提供鼠标模型资源和研究支持服务。此外，这些中心使用其专业知识来研究和实施新的相关技术。随着基因工程小鼠的生产显着增加，这些中心已经扩展到包括32,527多个突变体和遗传工程的小鼠菌株的库存，这些菌株保持了活菌落，冷冻保存的种质和胚胎（ES）细胞系，并填充了〜3550个以上的研究员，在2000年以上的研究员中填充了〜4,080个订单。在全国分布的多机构中 具有共同目标的计划，迫切需要高水平的协调沟通。通过电子邮件以及在所有中心的关键人员与NIH计划工作人员和定期电视会议之间的每月电视会议中讨论了日常运营，短期策略的管理和制定，以满足特定中心需求的子组。但是，没有真正代替定期面对面的会议。因此，该提案要求MMRRC的资金在未来五年内组织和计划年度会议。这样的年度会议至关重要1）提供足够的时间和面对面的互动来审查进度并讨论短期和长期计划策略，以确保MMRRC计划不断发展以满足科学社区的快速发展需求，并且2）为展示MMRRC官员和其他相关社区的MMRRC计划提供了一个场地，并提供了他们的科学社区和其他相关社区的成员。