Computational and mathematical modeling of biomedical systems

生物医学系统的计算和数学建模

• 批准号: 8508948
• 负责人: Timothy W. Secomb
• 金额: $ 17.97万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8508948
• 关键词: Computer Simulation; System; mathematical model

DESCRIPTION (provided by applicant): This program will prepare scientists for research careers in the computational analysis and mathematical modeling of medically significant biological systems through interdisciplinary training at the predoctoral level. Noted for its well-established system of interdisciplinary graduate programs and for its tradition of collaborations across departmental boundaries, the University of Arizona provides a highly suitable environment for such training. Seventeen training faculty and two associate faculty with appointments in multiple departments and interdisciplinary graduate programs provide strength in three broad areas: molecular dynamics; cellular processes; physiology and pathophysiology. Students will be drawn primarily from the interdisciplinary Program in Applied Mathematics and the cross-disciplinary Biochemistry and Molecular & Cellular Biology Program. Qualified students from other graduate programs will also be eligible. In most cases, students will receive support starting in their second year of graduate training. Trainees will pursue the coursework requirements of their own graduate programs and will, in addition, take graduate courses in bioinformatics, biostatistics and mathematical modeling tailored to their diverse scientific backgrounds. Trainees will take part in a weekly biomathematics colloquium that has been running continuously for more than a decade and promotes dialog between trainees and faculty with primarily mathematical or computational backgrounds and those with strong biological training. Trainees will carry out doctoral research with advisors whose research, whether theoretical or experimental, emphasizes application of theoretical approaches to biomedical problems. Where appropriate, a co-advisor will be appointed to provide complementary expertise to that of the primary advisor. Trainees participating in this program will not only receive research training in relevant areas, but will also develop the ability to communicate and collaborate across traditional disciplinary boundaries and to work with researchers with complementary expertise. Researchers with such skills are critically needed in many areas of biomedical science in which sophisticated theoretical approaches are necessary in order to achieve further progress. Relevance: In many areas of biomedical science, sophisticated theoretical approaches are necessary in order to achieve further progress. This program will prepare scientists for research careers in the computational analysis and mathematical modeling of medically significant biological systems through interdisciplinary training at the predoctoral level.

描述（由申请人提供）：该计划将通过博士前水平的跨学科培训，为科学家在具有医学意义的生物系统的计算分析和数学建模方面的研究生涯做好准备。亚利桑那大学以其完善的跨学科研究生课程体系和跨部门合作的传统而闻名，为此类培训提供了非常合适的环境。十七名培训教师和两名副教师在多个部门和跨学科研究生项目中任职，在三个广泛的领域提供优势：分子动力学；细胞过程；生理学和病理生理学。学生将主要来自应用数学跨学科项目和跨学科生物化学以及分子与细胞生物学项目。其他研究生课程的合格学生也有资格。在大多数情况下，学生将从研究生培训的第二年开始获得支持。学员将追求自己研究生课程的课程要求，此外还将参加针对其不同科学背景量身定制的生物信息学、生物统计学和数学建模研究生课程。学员将参加每周一次的生物数学研讨会，该研讨会已连续举办十多年，旨在促进学员和具有主要数学或计算背景以及受过良好生物训练的教师之间的对话。学员将与导师一起进行博士研究，导师的研究，无论是理论还是实验，都强调将理论方法应用于生物医学问题。在适当的情况下，将任命一名联合顾问为主要顾问提供补充专业知识。参加该项目的学员不仅将接受相关领域的研究培训，还将培养跨传统学科界限的沟通与协作以及与具有互补专业知识的研究人员合作的能力。生物医学科学的许多领域都迫切需要具有此类技能的研究人员，在这些领域中，需要复杂的理论方法才能取得进一步的进展。相关性：在生物医学的许多领域，为了取得进一步的进展，需要复杂的理论方法。该项目将通过博士前水平的跨学科培训，为科学家在具有医学意义的生物系统的计算分析和数学建模方面的研究生涯做好准备。