POSTNATAL REMODELING IN DIST AIRWAY OF INFANT MONKEYS EXP TO OZONE & ALLERGEN

暴露于臭氧的幼猴的产后呼吸道重塑

• 批准号: 8357245
• 负责人: DALLAS Melvin HYDE
• 金额: $ 7.56万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357245
• 关键词: Address; Air Pollutants; Allergens; Asthma; Bronchoconstriction; California; Childhood; Exposure to; Funding; Grant; Infant; Lung diseases; Monkeys; National Center for Research Resources; Nature; Oxidants; Ozone; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; cost; lung development; postnatal; respiratory smooth muscle

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Airway smooth muscle has been implicated in the excessive bronchoconstriction of asthma. The present study addressed the question of whether the episodic nature of urban exposure to oxidant air pollutants contributes to the rise in childhood respiratory diseases by altering postnatal lung development.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 气道平滑肌与哮喘的过度支气管收缩有关。本研究解决了城市暴露于氧化剂空气污染物的偶发性质是否通过改变产后肺部发育而导致儿童呼吸道疾病增加的问题。