RHESUS BREEDING COLONY IN NEPAL AND IMPORTATION TO USA

尼泊尔恒河猴养殖场并进口到美国

• 批准号: 8357648
• 负责人: JOHN L VANDEBERG
• 金额: $ 9.96万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357648
• 关键词: AIDS vaccine development; Acquired Immunodeficiency Syndrome; Address; Animal Experimentation; Animals; Biological; Biomedical Research; Breeding; Characteristics; Funding; Grant; Infectious Agent; Laws; Macaca mulatta; Monkeys; National Center for Research Resources; Nepal; Primates; Principal Investigator; Production; Research; Research Infrastructure; Resources; Severities; Source; United States; United States National Institutes of Health; cost; meetings; vaccine development; weapons; AIDS vaccine development; Acquired Immunodeficiency Syndrome; Address; Animal Experimentation; Animals; Biological; Biomedical Research; Breeding; Characteristics; Funding; Grant; Infectious Agent; Laws; Macaca mulatta; Monkeys; National Center for Research Resources; Nepal; Primates; Principal Investigator; Production; Research; Research Infrastructure; Resources; Severities; Source; United States; United States National Institutes of Health; cost; meetings; vaccine development; weapons

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. There is a severe shortage of rhesus monkeys (Macaca mulatta) required to fulfill critical needs in research on AIDS, on development of vaccines against infectious agents that could be used as biological weapons, and on a wide variety of other topics in biomedical research. Rhesus macaques derived from monkeys of Indian origin have unique characteristics that are particularly valuable in research on the development of AIDS vaccines. Despite the recent expansion of breeding colonies in the United States, the shortage of these important research animals is actually increasing in severity, accentuating the need for new sources of Indian-type rhesus. Indian-type rhesus macaques exist in large numbers throughout many regions of Nepal. The production and exportation of captive born rhesus macaques is approved under Nepalese law. The objective of this proposal is to address the urgent need for a new source of Indian-type rhesus macaques for use in biomedical research by developing a captive breeding colony in Nepal. We are developing a self-sustaining colony capable of supplying 75 animals per year to the US to meet critical biomedical research needs.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 在满足有关艾滋病研究的关键需求，针对可以用作生物武器的传染剂以及生物医学研究中各种各样的其他主题的疫苗开发疫苗的关键需求，开发疫苗的疫苗开发疫苗，需要严重缺乏恒河猴（Macaca mulatta）。 源自印度猴子的恒河猕猴具有独特的特征，这些特征对于研究艾滋病疫苗的开发特别有价值。 尽管最近在美国繁殖菌落的扩大，但这些重要的研究动物的短缺实际上正在增加严重程度，这加剧了对印度型恒河部新来源的需求。 在尼泊尔许多地区，印度型恒河猕猴都有大量存在。 根据尼泊尔法律批准了俘虏出生的恒河猕猴的生产和出口。 该提案的目的是通过在尼泊尔开发一个圈养的育种殖民地来解决新的印度型恒河猕猴的新来源，以用于生物医学研究。 我们正在开发一个自我维持的殖民地，能够每年向美国提供75只动物，以满足关键的生物医学研究需求。