HIV PrEP Perspectives of Liberian Adolescent Girls and Young Women and their Providers

利比里亚少女和年轻妇女及其提供者的 HIV PrEP 观点

• 批准号: 10619271
• 负责人: Onyema E. Ogbuagu
• 金额: $ 23.85万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-15 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10619271
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Administrator; Africa; Africa South of the Sahara; African; Attention; Attitude; Authorization documentation; Behavioral; Clinic; Collaborations; Complex; Consensus; Country; County; Cross-Sectional Studies; Data; Decision Making; Development; Disadvantaged; Eastern Africa; Eligibility Determination; Evaluation; Face; Family Planning; Female Adolescents; Formulation; Goals; HIV; HIV Infections; HIV vaccine; Health; Health Personnel; Injecting drug user; Intervention; Interview; Investigation; Knowledge; Leadership; Liberia; Liberian; Male Circumcision; Men' s Role; Methods; Modality; Modeling; Motivation; Oral; Participant; Perception; Perinatal; Pharmaceutical Preparations; Physicians; Policy Maker; Population; Populations at Risk; Prevalence; Prevention; Process; Program Development; Provider; Public Health; Reporting; Reproductive Health Services; Research Infrastructure; Research Methodology; Research Personnel; Respondent; Risk; Risk Reduction; Rural; Scientist; Site; Southern Africa; Structure; Techniques; Testing; Vertical Disease Transmission; Vulnerable Populations; Woman; Work; authority; condoms; design; experience; falls; girls; implementation strategy; infection risk; informant; interest; intervention mapping; male; men; men who have sex with men; pre-exposure prophylaxis; preference; programs; recruit; risk perception; rural area; sexual violence; sexually active adolescent; skills; social; transgender women; treatment as prevention; uptake; urban area; willingness; young woman

PROJECT SUMMARY/ABSTRACT Pre-Exposure Prophylaxis (PrEP) is becoming increasingly available in sub-Saharan Africa (SSA) and as a highly effective and user-controlled intervention for HIV prevention holds promise for those most at risk of infection including adolescent girls and young women (AGYW). However, most of the increased uptake of PrEP in SSA has been in a handful of countries with the world’s highest HIV rates, and where the HIV prevalence can influence risk perception and willingness to use PrEP. Despite the rise PrEP in these and other regions where it is available, most of those eligible for PrEP are not using it, and among those that do begin PrEP, discontinuation rates in the months after initiation is common, especially for AGYW, In West Africa, where HIV rates are lower but unacceptably high, PrEP is beginning to be rolled out. Public health authorities in Liberia have taken steps to integrate PrEP into the country’s HIV prevention programming and have recently started pilot clinics to administer PrEP to men who have sex with men, transgender women, and people who inject drugs. In 2023-24, PrEP will be expanded nationwide to include the largest key population AGYW. These policymakers are deeply interested in developing PrEP programming that is preference-sensitive and reflects determinants of PrEP engagement for AGYW in the West African context, which is distinct from those of other regions of Africa. Therefore, we propose to obtain an in-depth understanding of the PrEP perceptions and preferences among urban and rural AGYW in Liberia, their male partners, and healthcare providers – applying the situated Information, Motivation, and Behavioral Skills (sIMB) model to guide our investigations. In close collaboration with PrEP planners, we will then use Intervention Mapping framework processes to directly apply the formative data to the development of implementation planning for PrEP for AGYW. The resulting implementation options will serve as a roadmap for the critical next stage of PrEP roll-out in Liberia and serve as a model for similar settings.

项目概要/摘要 暴露前预防 (PrEP) 在撒哈拉以南非洲 (SSA) 越来越普及，并作为一种预防措施 高效且用户控制的艾滋病毒预防干预措施为那些最有可能感染艾滋病毒的人带来了希望 然而，大多数感染者都增加了 PrEP 的摄入量，其中包括青春期女孩和年轻女性 (AGYW)。 撒哈拉以南非洲的艾滋病毒感染率是世界上少数几个国家中艾滋病毒感染率最高的国家。 尽管 PrEP 在这些地区和其他地区有所增加，但仍影响风险认知和使用 PrEP 的意愿。 可用，大多数符合 PrEP 资格的人没有使用它，而在那些开始 PrEP 的人中，停止使用 开始后几个月的发病率很常见，特别是对于 AGYW， 在艾滋病毒感染率较低但高得令人难以接受的西非，PrEP 已开始向公众推广。 利比里亚卫生当局已采取措施将 PrEP 纳入该国的艾滋病毒预防规划 最近启动了试点诊所，向男男性行为者、跨性别女性、 2023-24 年，PrEP 将扩大到全国范围，以涵盖最大的重点人群。 AGYW。这些政策制定者对制定偏好敏感的 PrEP 规划非常感兴趣。 以及西非背景下 AGYW 的 PrEP 参与的反映，这与 因此，我们建议深入了解 PrEP。 利比里亚城乡 AGYW 及其男性伴侣和医疗保健的看法和偏好 提供商 – 应用情境信息、动机和行为技能 (sIMB) 模型来指导我们 然后，我们将与 PrEP 规划者密切合作，使用干预映射框架。 直接将形成性数据应用于制定 AGYW PrEP 实施计划的流程。 由此产生的实施方案将作为利比里亚下一阶段关键的 PrEP 推广的路线图 并作为类似设置的模型。