NIH-Owned Chimpanzee Research Resource at the SNPRC

NIH 拥有的 SNPRC 黑猩猩研究资源

基本信息

批准号：
8543216
负责人：
JOHN L VANDEBERG
金额：
$ 268.19万
依托单位：
TEXAS BIOMEDICAL RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-09-05 至 2016-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8543216
关键词：
Acquired Immunodeficiency Syndrome Address Aggressive behavior Animal Behavior Animals Behavior Therapy Behavioral Biochemical Biomedical Research Categories Characteristics Clinical Cognition Cognitive Communicable Diseases Communities Companions Complex Data Databases Disease Evolution Food Future Gene Expression Profile Genes Genetic HIV Health Status Heart Diseases Hepatitis Hepatitis B Virus Hepatitis C virus Housing Human Individual Infection Intervention Isoptera Liver Measures Messenger RNA MicroRNAs Modeling National Center for Research Resources Occupational Occupations Pan Genus Perch Peripheral Blood Mononuclear Cell Pharmaceutical Preparations Physiological Physiology Play Pongidae Population Primates Radio Recommendation Recording of previous events Relative (related person)Research Research Subjects Resources Role Sampling Schedule Sensory Services Socialization Specialist Structure Television Testing Toy Training United States National Institutes of Health Variant biomedical resource cohort design efficacy testing environmental enrichment for laboratory animals feeding fruits and vegetables humanized monoclonal antibodies intervention program man meetings novel novel therapeutic intervention programs public education safety testing social

项目摘要

The overall objective of this project is to maintain an NIH-owned biomedical resource consisting of 136 chimpanzees and to manage it to serve the national biomedical community needs. The sole specific aim of this supplement over the next year is to maintain a stable, healthy, and well defined population of chimpanzees and to coordinate the relocation of chimpanzees from the New Iberia Research Center to the Southwest National Primate Center. The transfer of the 111 NIH-owned chimpanzees currently located at the New Iberia center to the Southwest center will bring the total number of NIH-owned chimpanzees at Southwest to 136. Relocation details are provided separately. In addition to routine husbandry, high quality behavioral management and enrichment are critical for meeting the social and cognitive needs of the chimpanzees. Aspects of the behavioral services program at the Southwest center include socialization and animal training, environmental enrichment, behavioral management, and staff training. Categories of environmental enrichment include social enrichment (housing with compatible social companions), structural enrichment (e.g., climbing structures, perches. Swings), manipulable enrichment (e.g., chew toys and balls), food enrichment (4x daily fruit and vegetables in addition to special food treats provided by enrichment specialists), sensory enrichment (television, mirrors, radio, novel scents), and occupation enrichement (e.g. termite feeders and food puzzles). Behavioral management is a large part of the total program. In situations where behavioral concerns arise (e.g. increased aggression in a group), observations are conducted and recommendations are made to address the issue (e.g., cooperative feeding or reorganization of the group). With individual animal behavior problems, that animal is referred to the behavioral intervention program manager who conducts an assessment and develops an intervention plan (e.g., training/stationing, occupational enrichment such as food puzzles, or changes in the caretaker routine.

该项目的总体目标是维护 NIH 拥有的由 136 只黑猩猩组成的生物医学资源，并对其进行管理以满足国家生物医学界的需求。明年该补充的唯一具体目标是维持稳定、健康和明确的黑猩猩种群，并协调黑猩猩从新伊比利亚研究中心到西南国家灵长类动物中心的迁移。将目前位于新伊比利亚中心的 111 只 NIH 拥有的黑猩猩转移至西南中心，将使西南中心 NIH 拥有的黑猩猩总数达到 136 只。搬迁详情另行提供。除了日常饲养之外，高质量的行为管理和丰富对于满足黑猩猩的社交和认知需求至关重要。西南中心的行为服务项目包括社会化和动物训练、环境丰富、行为管理和员工培训。环境丰富的类别包括社交丰富（拥有兼容的社交伙伴的住房）、结构丰富（例如，攀爬结构、栖木、秋千）、可操作的丰富（例如，咀嚼玩具和球）、食物丰富（除了日常水果和蔬菜外，还提供 4 倍的水果和蔬菜）丰富专家提供的特殊食物）、感官丰富（电视、镜子、广播、新颖的气味）和职业丰富（例如白蚁喂食器和食物）谜题）。行为管理是整个计划的很大一部分。在出现行为问题的情况下（例如，群体中的攻击性增加），将进行观察并提出解决问题的建议（例如，合作喂养或重组群体）。对于个别动物的行为问题，该动物会被转介给行为干预计划经理，后者进行评估并制定干预计划（例如，训练/驻扎、职业丰富如食物谜题或看护者日常工作的改变）。