SUPPORT SERVICES FOR HIV AIDS CLINICAL TRIAL NETWORKS

HIV 艾滋病临床试验网络的支持服务

基本信息

批准号：
10872942
负责人：
BARBARA DRIVER
金额：
$ 272.52万
依托单位：
WESTAT, INC.
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-06-01 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10872942
关键词：
AIDS clinical trial group Acquired Immunodeficiency Syndrome Address Adolescent Adolescent Development Adolescent Medicine Trials Network Agreement Area Award Biological Assay Brazil Child Childhood Clinical Management Clinical Research Clinical Trials Clinical Trials Network Communicable Diseases Conduct Clinical Trials Contractor Contracts Country Data Analyses Diagnostic Procedure Epidemiology Equipment Ethnic Origin Evaluation Family Funding Grant HIV HIV Infections HIV Vaccine Trials Network HIV prevention trials network HIV vaccine HIV-infected adolescents HIV/AIDS Healthcare Human Development Human Resources Immunologics Infectious Diseases Research Infrastructure International International Maternal Pediatric Adolescent AIDS Clinical Trials Investigational Therapies Laboratories Lead Maintenance Mediation Medical Methodology Mission Monitor Mothers National Institute of Allergy and Infectious Disease National Institute of Child Health and Human Development Natural History Performance Pharmacy facility Prevention Prevention strategy Protocols documentation Quality Control Recurrence Reproductive Health Research Research Activity Research Personnel Resources Safety Sampling Security Services Shipping Site South Africa Specific qualifier value Specimen Specimen Handling System Testing Therapeutic Therapeutic Research Training Translations United States National Institutes of Health Woman Work adolescent health care coordination care systems clinical center clinical research site data management flexibility improved inner city laboratory equipment laboratory facility meetings minority children operation patient population pediatric human immunodeficiency virus pediatric human immunodeficiency virus infection pharmacologic programs protocol development quality assurance racial minority repository vaccine trial

项目摘要

The mission of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is to lead research and training to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize abilities for all. The Maternal and Pediatric Infectious Disease Branch (MPIDB) supports one of the major missions of the NICHD to enhance maternal, pediatric, and adolescent health and development. The objective or mission of this initiative is to provide support for critical infrastructure to enhance maternal, pediatric, and adolescent HIV therapeutics and prevention, including HIV vaccine research activities on a global scale. To provide opportunities to participate in therapeutic research, clinical trial centers must be situated in areas where infected women and children are located. Domestically, the vast majority of infected women and children are of minority race and ethnicity and often live in urban, inner-city areas in which the medical care system is often overwhelmed and under-funded. Internationally, continuing research in resource-limited countries is critical to address the global problem of pediatric HIV infection. The funding and conduct of clinical research in such settings offers many challenges though and requires a system that is flexible and responsive, and that ideally provides coordinated care of the mother and child together in a family-centered setting to optimize the maintenance of both woman and child in ongoing health care.

Eunice Kennedy Shriver国家儿童健康与人类发展研究所（NICHD）的使命是领导研究和培训，以了解人类发展，改善生殖健康，改善儿童和青少年的生活，并为所有人提供优化的能力。孕产妇和小儿传染病分支（MPIDB）支持NICHD的主要任务之一，以增强孕产妇，小儿和青少年的健康与发展。该计划的目标或使命是为关键基础设施提供支持，以增强母亲，儿科和青少年的HIV治疗剂和预防，包括全球范围内的HIV疫苗研究活动。为了提供参加治疗研究的机会，临床试验中心必须位于被感染的妇女和儿童的地区。在国内，绝大多数受感染的妇女和儿童都是少数族裔和种族，经常生活在城市内城市地区，其中医疗系统经常被不知所措和资金不足。在国际上，在资源有限的国家进行的继续研究对于解决儿童艾滋病毒感染的全球问题至关重要。但是，在这种情况下的临床研究的资金和行为提供了许多挑战，需要灵活且反应灵敏的系统，理想地在以家庭为中心的环境中为母亲和儿童提供了协调的护理，以优化持续医疗保健中妇女和儿童的维护。