VACCINES FOR CHLAMYDIA TRACHOMATIS INFECTIONS

沙眼衣原体感染疫苗

• 批准号: 8357310
• 负责人: LUIS M DE LA MAZA
• 金额: $ 2.52万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357310
• 关键词: California; Chlamydia trachomatis; Funding; Grant; Human; Immune response; Infection; Macaca mulatta; Modeling; National Center for Research Resources; Primates; Principal Investigator; Proteins; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; Vaccines; cost; nonhuman primate; preclinical study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this project is to demonstrate that Chlamydia trachomatis proteins stimulate vigorous immune responses in immunized rhesus macaques. This is a pre-clinical study in a nonhuman primate model with direct translational relevance to studies in humans.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 该项目的目的是证明沙眼衣原体蛋白会刺激免疫恒河猕猴中剧烈的免疫反应。 这是在非人类灵长类动物模型中进行的临床前研究，该模型与人类研究直接转化相关。