SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER

支持国家灵长类研究中心

• 批准号: 8122338
• 负责人: JOSEPH E ROBERTSON
• 金额: $ 1311.76万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-01 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8122338
• 关键词: SUPPORT; NATIONAL; PRIMATE; RESEARCH; CENTER

DESCRIPTION (provided by applicant): The 5-year renewal for Grant P51 RR00163-50 requests funding for programs at the ONPRC that support biomedical research. The application reflects a new strategic focus on interdisciplinary research to optimize the use and development of nonhuman primate (NHP) models. The aims of this application are to: 1) provide the infrastructure support necessary to conduct advanced biomedical research for which NHPs are used to accelerate progress in understanding human diseases; 2) enhance the Center?s resources (scientific expertise, laboratories, animal services, research support cores and equipment) so as to serve as a regional and national resource; 3) increase the availability of defined NHPs for biomedical research through support of our programs to expand the SPF Indian-origin rhesus macaque breeding program; and 4) expand research programs utilizing NHPs in stem cell biology, aging, obesity, genetics, infectious diseases, vaccine development, neuroscience and women?s health. To accomplish these aims, support is requested in three broad areas. First, Administration & Center Operations provide the administrative and service support required for all aspects of the ONPRC. Units include: 1) the Director?s Office; 2) Administrative Services (Business Services, Environmental Health & Radiation Safety, Facilities & Property, Information Technology & Engineering, and the Research Library); 3) Animal Resources (Administration, Operations, Behavioral Services, Pathology Services, Surgery Services, and Clinical Medicine); and 4) Research Support Cores (Assisted Reproductive Technology, Endocrine Technology, Imaging & Morphology, Immunology, Magnetic Resonance Imaging, Molecular & Cellular Biology, and Virology & Serology). Secondy, Scientific Components include support for: 1) Scientific Divisions (Neuroscience, Pathobiology & Immunology, and Reproductive Sciences) and their interdisciplinary Working Groups (Biology of Aging, Metabolic Disease, and Stem Cell & Developmental Biology); 2) the Collaborative Research Unit that facilitates externally funded research; 3) the Pilot Project Program; and 4) Resource-Related Research. Finally, Improvement & Modernization includes funds for equipment and alterations and renovations.

描述（由申请人提供）：P51 RR00163-50 的 5 年续展 请求为 ONPRC 支持生物医学研究的项目提供资金。该应用程序反映了 跨学科研究的新战略重点，以优化非人类的利用和开发 灵长类动物（NHP）模型。该应用程序的目的是：1）提供基础设施支持 进行先进的生物医学研究所必需的，其中 NHP 用于加速进展 了解人类疾病； 2) 增强中心的资源（科学专业知识、实验室、 动物服务、研究支持核心和设备），以便作为区域和国家 资源； 3) 通过我们的支持，增加用于生物医学研究的特定 NHP 的可用性 扩大 SPF 印度原产恒河猴繁殖计划的计划； 4）扩大研究范围 在干细胞生物学、衰老、肥胖、遗传学、传染病、疫苗等领域利用 NHP 的项目 发展、神经科学和妇女健康。为了实现这些目标，需要以下方面的支持： 三大领域。首先，行政和中心运营提供行政和服务 ONPRC 的各个方面都需要支持。单位包括： 1）主任办公室； 2) 行政 服务（商业服务、环境健康与辐射安全、设施与财产、 信息技术与工程以及研究图书馆）； 3）动物资源 （行政、操作、行为服务、病理学服务、手术服务和临床 药品）; 4) 研究支持核心（辅助生殖技术、内分泌技术、 成像与形态学、免疫学、磁共振成像、分子与细胞生物学，以及 病毒学和血清学）。其次，科学组件包括对以下方面的支持：1) 科学部门 （神经科学、病理生物学和免疫学以及生殖科学）及其跨学科 工作组（衰老生物学、代谢疾病、干细胞与发育生物学）； 2） 促进外部资助研究的合作研究单位； 3) 试点项目计划； 4) 资源相关研究。最后，改进和现代化包括以下方面的资金： 设备以及改建和翻新。