TARGETING NEUROTROPHIC FACTOR RECEPTORS TO BLOCK PAIN IN SCHWANNOMATOSIS

靶向神经营养因子受体来阻止神经鞘瘤病的疼痛

• 批准号: 8357885
• 负责人: Larry S. Sherman
• 金额: $ 3.63万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357885
• 关键词: Funding; Grant; National Center for Research Resources; Nerve Growth Factor Receptors; Pain; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Schwannomatosis; Signal Transduction; Source; Testing; United States National Institutes of Health; cost; mouse model; neurotrophic factor; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This project is to test if agents that block neurotrophic factor signaling can reverse pain responses in a mouse model of schwannomatosis.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 该项目是为了测试阻断神经营养因子信号传导的药物是否会在小鼠造型症模型中逆转疼痛反应。