Research Education Component (REC)

研究教育部分（REC）

• 批准号: 10729792
• 负责人: Ana-Maria Vranceanu
• 金额: $ 26.57万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729792
• 关键词: Academy; Address; Affect; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer' s disease risk; Area; Award; Behavior Therapy; Behavioral Research; Benchmarking; Biological; Biological Markers; Biology; Black race; Boston; Caring; Centers for Disease Control and Prevention (U.S.); Clinic; Clinical; Collaborations; Communities; Data; Dementia; Development; Development Plans; Diagnosis; Disease; Elderly; Ensure; Evaluation; Faculty; First Generation College Students; Fostering; Funding; General Hospitals; Goals; Grant; Growth; Health Alliance; Health Disparities Research; Hospitals; Infrastructure; Institution; Knowledge; Latino; Lead; Leadership; Link; Massachusetts; Measurement; Medical center; Medicine; Mentors; Mentorship; Minor; Minority; Minority Groups; Minority Health Research; Minority Recruitment; Modeling; Names; Neuropsychology; Participant; Patients; Persons; Pilot Projects; Population; Prevention; Preventive; Primary Prevention; Process; Psychologist; Qualitative Evaluations; Research; Research Personnel; Resource Sharing; Resources; Science; Scientific Advances and Accomplishments; Scientist; Secondary Prevention; Testing; Time; Translating; United States National Institutes of Health; Universities; Woman; Work; behavior change; behavioral health; behavioral health intervention; career; career development; community engaged research; community partnership; community setting; dementia risk; digital health; disorder prevention; education research; ethnic minority; health disparity; informal care; interest; minority patient; novel; programs; racial minority; recruit; research study; statistics; success; symposium; tertiary prevention; therapy development; training opportunity

The aim of the Research Education Component (REC) is to grow infrastructure and provide mentorship and pilot funding to early career investigators from underrepresented in medicine (UiM) backgrounds as delineated by NIH and this RFA (e.g., racial and ethnic minorities, women, first generation college students) who are interested in the developing, testing and implementing behavioral interventions for minority ADRD patients, care partners and dyads, following the revised NIH Stage Model, the Science of Behavior Change, the NIH Health Disparities Research Framework and the Center for Disease Prevention and National Academy of Medicine Prevention models. The REC will work closely with the Community Liaison and Recruitment Core (CLRC) and with the Massachusetts Alzheimer’s Disease Research Center (MADRC) and Boston University ADRC (BU-ADRC) RECs (both focused primarily on biomarkers) to allow for crosspollination of resources and knowledge including translating novel biological mechanisms into behavioral health intervention targets. The REC will support: 1) mentoring in ADRD and interdisciplinary behavioral research; 2) mentoring in health disparities, minority aging and community engaged research; 3) developing of a pilot studies program to support UiM early career investigators. Rates of ADRD are increasing drastically, with the greatest burden among minorities. Much of ADRD research has been focused on understanding the biology of disease, with less focus on behavioral health interventions for primary, secondary and tertiary prevention. Further, the burden of ADRD impacts not only the affected persons but also their informal care partners. There is a critical need for research to translate scientific advances into behavioral health interventions in both community and hospital settings to decrease ADRD burden for minority patients, care partners and dyads. The REC will directly address this need by leveraging: the interdisciplinary expertise at Massachusetts General Hospital (MGH), Boston Medical Center (BMC), Cambridge Health Alliance and affiliated clinics; the outstanding resources of Harvard and Boston University including MADRC, BU-ADRC; a NIA funded behavioral health ADRD R25; and numerous other important collaborators in the Boston area. The REC will also work closely to integrate activities and mentoring with other AD/ADRD RCMARs. The REC will be co-led by Ana-Maria Vranceanu (clinical psychologist) with expertise in behavioral health, ADRD, health disparities and community-engaged research, and a strong track record of mentoring, and Maureen O’Connor (clinical psychologist) who has expertise in ADRD and neuropsychology and leads the BU-ADRC REC. Specific aims are: 1) to develop and support a pilot project program (3 pilots/year; $40,000 each) from UiM investigators that fit the theme of the center; 2) to support the career development of pilot awardees (who will be named RCMAR Scientists) through a rigorous mentoring program; 3) to support mentoring of RCMAR Scientists in health disparities, ADRD and behavioral interventions following the NIH Stage Model, NIA Health Disparities Framework, and CDC and NAM prevention models; 4) to develop and implement an evaluation plan for aims 1, 2 and 3 in coordination with the Leadership and Administrative core of Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION).

研究教育部分 (REC) 的目标是发展基础设施并提供指导和试点资金 NIH 和本 RFA 所描述的医学 (UiM) 背景中代表性不足的早期职业研究人员 对开发、测试感兴趣的人（例如少数族裔、女性、第一代大学生） 根据修订后的 NIH，对少数 ADRD 患者、护理伙伴和夫妻实施行为干预 阶段模型、行为改变科学、NIH 健康差异研究框架和疾病中心 预防和国家医学科学院预防模型将与社区联络员密切合作。 和招聘核心 (CLRC) 以及马萨诸塞州阿尔茨海默病研究中心 (MADRC) 和波士顿 大学 ADRC (BU-ADRC) REC（均主要关注生物标志物），以实现资源的异花授粉和 REC 将包括将新的生物机制转化为行为健康干预目标。 支持：1) ADRD 和跨学科行为研究方面的指导；2) 健康差异、少数族裔老龄化方面的指导； 和社区参与的研究；3）制定试点研究计划以支持 UIM 早期职业调查人员。 ADRD 的发病率正在急剧增加，其中少数民族的负担最大，大部分 ADRD 研究都集中在这一点上。 侧重于了解疾病的生物学，较少关注初级、中级和初级阶段的行为健康干预措施 此外，ADRD 的负担不仅影响受影响者，还影响他们的非正式护理伙伴。 迫切需要将科学进步转化为两个社区的行为健康干预措施的研究 REC 将直接解决减少少数族裔患者、护理伙伴和夫妻的 ADRD 负担的医院环境。 通过利用以下机构的跨学科专业知识来满足这一需求：马萨诸塞州总医院 (MGH)、波士顿医疗中心的跨学科专业知识 (BMC)、剑桥健康联盟及附属诊所的哈佛大学和波士顿大学的优秀资源； 包括 MADRC、BU-ADRC；NIA 资助的行为健康 ADRD R25 以及许多其他重要合作者； REC 还将与其他 AD/ADRD RCMAR 密切合作，整合活动和指导。 REC 将由 Ana-Maria Vranceanu（临床心理学家）共同领导，她在行为健康、ADRD、健康方面拥有专业知识 差异和社区参与的研究，以及良好的指导记录，以及 Maureen O’Connor（临床 心理学家），拥有 ADRD 和神经心理学方面的专业知识，并领导 BU-ADRC REC 具体目标是： 1) 制定并支持由 UiM 研究人员提供的符合主题的试点项目计划（每年 3 名试点；每人 40,000 美元） 2) 通过严格的培训支持试点获奖者（将被命名为 RCMAR 科学家）的职业发展 指导计划；3) 支持 RCMAR 科学家在健康差异、ADRD 和行为干预方面的指导 遵循 NIH 阶段模型、NIA 健康差异框架以及 CDC 和 NAM 预防模型 4) 制定； 与领导和行政核心协调实施目标 1、2 和 3 的评估计划 马萨诸塞州阿尔茨海默病和痴呆症少数群体行为研究中心 (Mass-ENVISION)。