Research Education Component (REC)

研究教育部分（REC）

• 批准号: 10729792
• 负责人: Ana-Maria Vranceanu
• 金额: $ 26.57万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729792
• 关键词: Academy; Address; Affect; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer' s disease risk; Area; Award; Behavior Therapy; Behavioral Research; Benchmarking; Biological; Biological Markers; Biology; Black race; Boston; Caring; Centers for Disease Control and Prevention (U.S.); Clinic; Clinical; Collaborations; Communities; Data; Dementia; Development; Development Plans; Diagnosis; Disease; Elderly; Ensure; Evaluation; Faculty; First Generation College Students; Fostering; Funding; General Hospitals; Goals; Grant; Growth; Health Alliance; Health Disparities Research; Hospitals; Infrastructure; Institution; Knowledge; Latino; Lead; Leadership; Link; Massachusetts; Measurement; Medical center; Medicine; Mentors; Mentorship; Minor; Minority; Minority Groups; Minority Health Research; Minority Recruitment; Modeling; Names; Neuropsychology; Participant; Patients; Persons; Pilot Projects; Population; Prevention; Preventive; Primary Prevention; Process; Psychologist; Qualitative Evaluations; Research; Research Personnel; Resource Sharing; Resources; Science; Scientific Advances and Accomplishments; Scientist; Secondary Prevention; Testing; Time; Translating; United States National Institutes of Health; Universities; Woman; Work; behavior change; behavioral health; behavioral health intervention; career; career development; community engaged research; community partnership; community setting; dementia risk; digital health; disorder prevention; education research; ethnic minority; health disparity; informal care; interest; minority patient; novel; programs; racial minority; recruit; research study; statistics; success; symposium; tertiary prevention; therapy development; training opportunity

The aim of the Research Education Component (REC) is to grow infrastructure and provide mentorship and pilot funding to early career investigators from underrepresented in medicine (UiM) backgrounds as delineated by NIH and this RFA (e.g., racial and ethnic minorities, women, first generation college students) who are interested in the developing, testing and implementing behavioral interventions for minority ADRD patients, care partners and dyads, following the revised NIH Stage Model, the Science of Behavior Change, the NIH Health Disparities Research Framework and the Center for Disease Prevention and National Academy of Medicine Prevention models. The REC will work closely with the Community Liaison and Recruitment Core (CLRC) and with the Massachusetts Alzheimer’s Disease Research Center (MADRC) and Boston University ADRC (BU-ADRC) RECs (both focused primarily on biomarkers) to allow for crosspollination of resources and knowledge including translating novel biological mechanisms into behavioral health intervention targets. The REC will support: 1) mentoring in ADRD and interdisciplinary behavioral research; 2) mentoring in health disparities, minority aging and community engaged research; 3) developing of a pilot studies program to support UiM early career investigators. Rates of ADRD are increasing drastically, with the greatest burden among minorities. Much of ADRD research has been focused on understanding the biology of disease, with less focus on behavioral health interventions for primary, secondary and tertiary prevention. Further, the burden of ADRD impacts not only the affected persons but also their informal care partners. There is a critical need for research to translate scientific advances into behavioral health interventions in both community and hospital settings to decrease ADRD burden for minority patients, care partners and dyads. The REC will directly address this need by leveraging: the interdisciplinary expertise at Massachusetts General Hospital (MGH), Boston Medical Center (BMC), Cambridge Health Alliance and affiliated clinics; the outstanding resources of Harvard and Boston University including MADRC, BU-ADRC; a NIA funded behavioral health ADRD R25; and numerous other important collaborators in the Boston area. The REC will also work closely to integrate activities and mentoring with other AD/ADRD RCMARs. The REC will be co-led by Ana-Maria Vranceanu (clinical psychologist) with expertise in behavioral health, ADRD, health disparities and community-engaged research, and a strong track record of mentoring, and Maureen O’Connor (clinical psychologist) who has expertise in ADRD and neuropsychology and leads the BU-ADRC REC. Specific aims are: 1) to develop and support a pilot project program (3 pilots/year; $40,000 each) from UiM investigators that fit the theme of the center; 2) to support the career development of pilot awardees (who will be named RCMAR Scientists) through a rigorous mentoring program; 3) to support mentoring of RCMAR Scientists in health disparities, ADRD and behavioral interventions following the NIH Stage Model, NIA Health Disparities Framework, and CDC and NAM prevention models; 4) to develop and implement an evaluation plan for aims 1, 2 and 3 in coordination with the Leadership and Administrative core of Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION).

研究教育部分（REC）的目的是发展基础设施并提供指导和试点资金 NIH和此RFA所描绘的医学背景（UIM）背景的早期职业调查员（UIM）背景 （例如，种族和少数民族，妇女，第一代大学生）对发展，测试感兴趣的人 并在修订后的NIH之后针对少数ADRD患者，护理伙伴和二元组实施行为干预措施 舞台模型，行为改变科学，NIH健康差异研究框架和疾病中心 预防和国家医学学院预防模型。 REC将与社区联络密切合作 和招聘核心（CLRC）以及马萨诸塞州阿尔茨海默氏病研究中心（MADRC）和波士顿 大学ADRC（BU-ADRC）REC（均主要针对生物标志物），以允许对资源进行交叉授粉和 知识包括将新颖的生物学机制转化为行为健康干预目标。 Rec Will 支持：1）在ADRD和跨学科行为研究中进行心理； 2）健康差异，少数族裔老化 和社区参与研究； 3）制定试点研究计划，以支持UIM早期职业研究者。费率 ADRD的越来越大，少数民族之间的燃烧最大。 ADRD的大部分研究都集中在 在理解疾病的生物学方面，对初级，次要和 第三级预防。此外，ADRD的燃烧不仅影响受影响的人，而且影响其非正式护理伙伴。 研究需要将科学进步转化为两个社区的行为健康干预措施 以及医院的环境，以减少少数族裔患者，护理伴侣和二元组的ADRD烧伤。 REC将直接解决 利用这种需求：马萨诸塞州综合医院（MGH）的跨学科专业知识 （BMC），剑桥卫生联盟和会员诊所；哈佛大学和波士顿大学的杰出资源 包括Madrc，Bu-Adrc； NIA资助的行为健康ADRD R25；以及许多其他重要的合作者 在波士顿地区。 REC还将紧密合作将活动和心理与其他广告/ADRD RCMARS整合在一起。 REC将由Ana-Maria Vranceanu（临床心理学家）共同领导，其行为健康方面的专业知识，ADRD，健康 差异和社区参与研究，以及良好的心理记录，莫琳·奥康纳（Maureen O’Connor）（临床） 心理学家）在ADRD和神经心理学方面具有专业知识，并领导Bu-Adrc Rec。具体目的是：1） 从UIM调查人员制定和支持一项试点项目计划（每年3条管道/40,000美元），该计划适合该主题 中心; 2）通过严格的 心理计划； 3）支持RCMAR科学家在健康分布，ADRD和行为干预中的心理 遵循NIH阶段模型，NIA健康差异框架以及CDC和NAM预防模型； 4）开发 并针对目标1、2和3实施评估计划，以与领导和行政核心协调 马萨诸塞州阿尔茨海默氏症和痴呆症行为研究中心（群众范围）。